Kentucky Route 80 (KY 80) is a 483.55-mile-long (778.20 km) state highway in the southern part of the U.S. state of Kentucky. The route originates on the state's western border at Columbus in Hickman County and stretches across the southern portion of the state, terminating southeast of Elkhorn City on the Virginia state line. It is the longest Kentucky State Highway, though the official distance as listed in route logs is much less due to multiple concurrencies with U.S. Route 68 (US 68) and US 23.
The William H. Natcher Green River Parkway was the designation for a 72.3-mile (116.4 km) freeway that ran from Bowling Green to Owensboro in the US commonwealth of Kentucky. The Natcher Parkway was one of nine highways that were a part of Kentucky's parkway system. The portion north of Interstate 65 (I-65) was signed as I-165, and the portion south of I-65 as Kentucky Route 9007 on March 6, 2019.
The Louie B. Nunn Cumberland Expressway is a 88.4-mile (142.3 km) freeway in the U.S. state of Kentucky, extending from Barren County in the west to Somerset in the east. It is one of seven named highways designated in Kentucky's parkway system.
The Wendell H. Ford Western Kentucky Parkway is a 98.5-mile-long (158.5 km) freeway running from Elizabethtown to near Nortonville, Kentucky. It intersects with Interstate 65 (I-65) at its eastern terminus, and I-69 at its western terminus. It is one of seven highways that are part of the Kentucky parkway system. The road was renamed for Wendell H. Ford, a former Kentucky governor and United States senator, in 1998. Previously, it was simply the Western Kentucky Parkway, and often called the "WK Parkway" or "the WK" because of the initials that were once used on its signs prior to the 1998 renaming. The parkway carries the unsigned designation Kentucky Route 9001 for its entire length.
The Julian M. Carroll Purchase Parkway was the designation for a 52.3-mile (84.2 km) freeway in the U.S. state of Kentucky that ran between the Tennessee state line at Fulton and US 62 in Calvert City. It began concurrent with U.S. Route 51 only a few yards from an intersection with US 45W, US 45E, and US 45 at its southern terminus. It was one of seven highways that are part of the Kentucky Parkway System. The parkway was upgraded to Interstate Highway standards and incorporated into I-69 in two phases. The northern half between US 45 Bypass in Mayfield and I-24 near Calvert City was redesignated as I-69 in July 2018. The interchange with I-24 was reconstructed from a basic cloverleaf interchange to include a pair of direct high-speed connectors for I-69 through traffic continuing east concurrent with I-24, with the northernmost 1.67 miles (2.69 km) of the parkway becoming exit 51A-B and facilitating access to westbound I-24 and US 62 for northbound traffic. The Kentucky Transportation Cabinet (KYTC) acquired and closed the nearby Kentucky Lake Motor Speedway in 2015 via eminent domain for the reconstruction of the interchange. The southern half of the parkway from the Tennessee state line in Fulton to US 45 Bypass in Mayfield was redesignated as I-69 in December 2024.
The Edward T. Breathitt Pennyrile Parkway was the designation for a 71.3-mile (114.7 km) freeway from Henderson to Hopkinsville, Kentucky. The parkway originally began at an interchange with the Audubon Parkway and US 41 near the city of Henderson. It travelled south through rolling hills to its former southern terminus at Interstate 24 (I-24) south of Hopkinsville. A seven-mile (11 km) section was left unconstructed from US 41 Alternate south to I-24 despite its approval in 1976 from the Parkway Authority for construction. This connection was completed and opened to the public on March 1, 2011. The first 1.8 miles (2.9 km) of the extension to the US 68 bypass were completed and opened to traffic in September 2008. The construction was then completed to exit 5, with the final section to I-24 opened on March 1, 2011. The parkway's northern terminus was truncated south to the Western Kentucky Parkway in 2013 when Interstate 69 was extended along that section of the highway. The remaining section of the Parkway was redesignated as Interstate 169 in December 2024, thereby replacing the last section of the Pennyrile Parkway.
U.S. Route 31W is the westernmost of two parallel routes for U.S. Route 31 from Nashville, Tennessee to Louisville, Kentucky.
U.S. Route 25E (US 25E) is the eastern branch of US 25 from Newport, Tennessee, where US 25 splits into US 25E and US 25W, to North Corbin, Kentucky, where the two highways rejoin. The highway, however, continues as US 25E for roughly two miles (3.2 km) until it joins Interstate 75 (I-75) in the Laurel County community of North Corbin at exit 29. The highway serves the Appalachia regions of Kentucky's Cumberland Plateau and the Ridge-and-Valley section of East Tennessee, including the urbanized areas of Corbin and Middlesboro in Kentucky and Morristown in Tennessee.
The Bert T. Combs Mountain Parkway, commonly known as the Mountain Parkway, is a freeway in eastern Kentucky. The route runs from Interstate 64 (I-64) just east of Winchester southeast for 75.6 miles (121.7 km) to a junction with U.S. Route 460 (US 460) near Salyersville. The first 46 miles (74 km), beginning at the western terminus in Winchester is a four-lane freeway with only minor design standard differences from an Interstate Highway, while the remainder is a limited access super two highway.
Kentucky Route 11 (KY 11) is an American highway maintained by the Kentucky Transportation Cabinet that runs from Maysville to Barbourville. The route from Maysville to Mount Sterling is being upgraded on a new alignment as part of a "macro-corridor" within the state of Kentucky.
Interstate 69 (I-69) in the U.S. state of Kentucky is a 148.1-mile-long (238.3 km) Interstate Highway running from the Tennessee state line in the southwest at Fulton to Henderson in the northeast, just south of the Ohio River. The route incorporates much of the former state parkway system, including the entire Purchase Parkway from Fulton to Calvert City, the western third of the Western Kentucky Parkway from Eddyville to Nortonville, and the northern half of the Pennyrile Parkway from Nortonville to Henderson. Between Calvert City and Eddyville, I-69 runs concurrently with I-24. Eventually, I-69 will leave the former Pennyrile Parkway just south of the Audubon Parkway interchange to bypass Henderson to the east before heading north into Indiana. The proposed route for the remainder of I-69 in Kentucky travels about 10 miles (16 km) before exiting on a bridge across the Ohio River to Indiana; construction on the first segment began in 2022, with completion scheduled in 2031.
Interstate 75 (I-75) is a part of the Interstate Highway System that runs 1,786.47 miles (2,875.04 km) from Miami Lakes, Florida to the Canada–United States border at Sault Ste. Marie, Michigan. In the U.S. state of Kentucky, I-75 runs through the eastern half of the state, from the Tennessee state line near the city of Williamsburg to the Ohio state line near Covington. The Interstate serves the state's second-most populous city, Lexington. Outside of it, the route is mostly rural or suburban in nature, mainly providing access to other cities via state and U.S. Highways. The major landscapes traversed by I-75 include the rolling hills and mountains of the Cumberland Plateau, the flat Bluegrass region, the urban core of Lexington, and the highly urbanized suburbs of Northern Kentucky; it also very briefly crosses through the Eastern Kentucky Coalfield at its southernmost stretch and passes near the Daniel Boone National Forest in London.
Kentucky Route 212 is a short state highway located in Boone County, in the northern region of the U.S. state of Kentucky. The highway is approximately 1.3 miles (2.1 km) long, and partially constructed as a freeway, with the rest being a divided highway. The roadway links Interstate 275 (I-275) to the Cincinnati/Northern Kentucky International Airport, and has been designated as a connector route by the Federal Highway Administration (FHWA). A road first appeared near the location of KY 212 around 1937. A short road was built in the location of KY 212 when the U.S. Army Air Corps built the predecessor to the CVG Airport. The road was reconstructed to a divided highway in 1972, but was part of KY 1334 until 1974 or later, when KY 212 was designated, and KY 1334 was rerouted via Loomis Road and Whitson Drive to end at KY 20.
Interstate 65 (I-65) is part of the Interstate Highway System that runs 887.30 miles (1,427.97 km) north–south from Mobile, Alabama, to Gary, Indiana. The highway crosses Kentucky from south to north, from the Tennessee state line near Franklin to the Indiana state line in Louisville. I-65 passes through three of Kentucky's ten largest cities—Bowling Green, Elizabethtown, and Louisville—and serves Mammoth Cave National Park and Fort Knox. Kentucky was the first state to complete its portion of I-65, with the final section, located near Franklin, opening in 1970.
Kentucky Route 259 is a 95.91-mile-long (154.35 km) state highway that traverses five counties in west-central Kentucky.
U.S. Route 41 in the state of Kentucky is a north–south United States Numbered Highway that runs from Miami, Florida, to Copper Harbor, Michigan. In Kentucky, the highway is primarily paralleled by the Pennyrile Parkway and Interstate 69. It enters Kentucky in the Todd County community of Guthrie, and leaves the state north of Henderson into Evansville. The total length of US 41 through Kentucky is a total of 106.952 miles (172.123 km).
U.S. Route 231 in Kentucky runs 114 miles (183 km) from the Tennessee state line near Adolphus to the William H. Natcher Bridge on the Ohio River near Rockport, Indiana. It crosses the state mainly in the west-central region, traversing Allen, Warren, Butler, Ohio, and Daviess Counties.
Veterans Outer Loop is a major bypass route in Glasgow, Kentucky. It is maintained by the Kentucky Transportation Cabinet (KYTC).
Kentucky Route 192 (KY 192) is a 40.5-mile-long (65.2 km) state highway in the U.S. state of Kentucky. The highway connects the Somerset area and the London areas with mostly rural areas of Pulaski and Laurel counties.
Kentucky Route 3145 is a rural-secondary state highway located entirely in Warren County in South Central Kentucky. The route serves as a connector between U.S. Route 31W and Interstate 65 (I-65) on the far east side of Bowling Green.
US 27 / KY 80 in Somerset 
