Kerri Pratt | |
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Alma mater | University of California, San Diego Pennsylvania State University |
Scientific career | |
Institutions | University of Michigan Purdue University |
Thesis | New insights into single-particle mixing state using aircraft aerosol time-of-flight mass spectrometry (2009) |
Website | Pratt Lab |
Kerri Pratt is an American chemist and Associate Professor of Chemistry at the University of Michigan. Her research considers atmospheric chemistry and how it impacts human health. She studies the interactions of atmospheric gases using mass spectrometry based techniques.
Pratt was an undergraduate student at Pennsylvania State University, where she originally majored in environmental science but eventually switched to chemistry. [1] She moved to the University of California, San Diego for graduate studies, where she worked toward a doctorate in time of flight mass spectrometry. [2] Her doctoral research was supervised by Kimberly Prather. [1] She was a postdoctoral researcher at Purdue University. [3] [4]
Pratt works in atmospheric chemistry. She was appointed to the faculty at the University of Michigan in 2013. [5] She is interested in various chemical reactions that occur in the environment, including those that occur between trace gases, in aqueous solutions and on surfaces. [6] Primary atmospheric particles can originate from natural and human-made sources, which include sea spray, soot and bacteria. [3] These undergo various reactions and can form secondary atmospheric particles, evolving into dynamical chemical mixtures such as aerosols. [7] These particles can take on a variety of different sizes, between 3 nm and 10 μm. Pratt investigates the interactions between trace gases and clouds using mass spectrometry. She is particularly interested in the atmospheric composition of winter environments, for example, in the Polar regions. [8] [9] The Arctic is undergoing a rapid loss of sea ice. [3] [10]
Pratt makes use of mass spectrometries to various degrees of sensitivity, for examples aerosol time-of-flight mass spectrometry (aerosols of 0.07 – 1.6 μm diameter), chemical ionization mass spectrometry (gases at sub parts per trillion) and ambient ion mass spectrometry. These results are combined with one-dimensional modelling to understand how atmospheric compositions as a function of altitude and time. She looks to establish the feedbacks between human-made emissions, aerosols and the Earth to better predict air quality. [3] In 2018, she started a United States Department of Energy project to use single particle mass spectrometry during the Polar night. [11] These measurements were combined with data collected from aerosol samples on the German icebreaker RV Polarstern. [11]
An ion source is a device that creates atomic and molecular ions. Ion sources are used to form ions for mass spectrometers, optical emission spectrometers, particle accelerators, ion implanters and ion engines.
Ion mobility spectrometry (IMS) It is a method of conducting analytical research that separates and identifies ionized molecules present in the gas phase based on the mobility of the molecules in a carrier buffer gas. Even though it is used extensively for military or security objectives, such as detecting drugs and explosives, the technology also has many applications in laboratory analysis, including studying small and big biomolecules. IMS instruments are extremely sensitive stand-alone devices, but are often coupled with mass spectrometry, gas chromatography or high-performance liquid chromatography in order to achieve a multi-dimensional separation. They come in various sizes, ranging from a few millimeters to several meters depending on the specific application, and are capable of operating under a broad range of conditions. IMS instruments such as microscale high-field asymmetric-waveform ion mobility spectrometry can be palm-portable for use in a range of applications including volatile organic compound (VOC) monitoring, biological sample analysis, medical diagnosis and food quality monitoring. Systems operated at higher pressure are often accompanied by elevated temperature, while lower pressure systems (1–20 hPa) do not require heating.
The Max Planck Institute for Chemistry is a non-university research institute under the auspices of the Max Planck Society in Mainz, Germany. It was created as the Kaiser Wilhelm Institute for Chemistry in 1911 in Berlin.
Atmospheric pressure chemical ionization (APCI) is an ionization method used in mass spectrometry which utilizes gas-phase ion-molecule reactions at atmospheric pressure (105 Pa), commonly coupled with high-performance liquid chromatography (HPLC). APCI is a soft ionization method similar to chemical ionization where primary ions are produced on a solvent spray. The main usage of APCI is for polar and relatively less polar thermally stable compounds with molecular weight less than 1500 Da. The application of APCI with HPLC has gained a large popularity in trace analysis detection such as steroids, pesticides and also in pharmacology for drug metabolites.
Thermospray is a soft ionization source by which a solvent flow of liquid sample passes through a very thin heated column to become a spray of fine liquid droplets. As a form of atmospheric pressure ionization in mass spectrometry these droplets are then ionized via a low-current discharge electrode to create a solvent ion plasma. A repeller then directs these charged particles through the skimmer and acceleration region to introduce the aerosolized sample to a mass spectrometer. It is particularly useful in liquid chromatography-mass spectrometry (LC-MS).
Robert Graham Cooks is the Henry Bohn Hass Distinguished Professor of Chemistry in the Aston Laboratories for Mass Spectrometry at Purdue University. He is an ISI Highly Cited Chemist, with over 1,000 publications and an H-index of 144.
Fred Warren McLafferty was an American chemist known for his work in mass spectrometry. He is best known for the McLafferty rearrangement reaction that was observed with mass spectrometry. With Roland Gohlke, he pioneered the technique of gas chromatography–mass spectrometry. He is also known for electron-capture dissociation, a method of fragmenting gas-phase ions.
Renato Zenobi is a Swiss chemist. He is Professor of Chemistry at ETH Zurich. Throughout his career, Zenobi has contributed to the field of analytical chemistry.
Extractive electrospray ionization (EESI) is a spray-type, ambient ionization source in mass spectrometry that uses two colliding aerosols, one of which is generated by electrospray. In standard EESI, syringe pumps provide the liquids for both an electrospray and a sample spray. In neutral desorption EESI (ND-EESI), the liquid for the sample aerosol is provided by a flow of nitrogen.
Aerosol mass spectrometry is the application of mass spectrometry to the analysis of the composition of aerosol particles. Aerosol particles are defined as solid and liquid particles suspended in a gas (air), with size range of 3 nm to 100 μm in diameter and are produced from natural and anthropogenic sources, through a variety of different processes that include wind-blown suspension and combustion of fossil fuels and biomass. Analysis of these particles is important owing to their major impacts on global climate change, visibility, regional air pollution and human health. Aerosols are very complex in structure, can contain thousands of different chemical compounds within a single particle, and need to be analysed for both size and chemical composition, in real-time or off-line applications.
Barbara J. Finlayson-Pitts is a Canadian-American atmospheric chemist. She is a professor in the chemistry department at the University of California, Irvine and is the Director of AirUCI Institute. Finlayson-Pitts and James N. Pitts, Jr. are the authors of Chemistry of the Upper and Lower Atmosphere: Theory, Experiments, and Applications (1999). She has been a member of the National Academy of Sciences since 2006 and is the laureate for the 2017 Garvan–Olin Medal. In 2016 she co-chaired the National Academy of Science report "The Future of Atmospheric Chemistry Research"
Gary Glish is an American analytical chemist at the University of North Carolina at Chapel Hill. He is a leading researcher in the fields of mass spectrometry, ion chemistry, and biomolecule analysis.
Kimberly A. Prather is an American atmospheric chemist. She is a distinguished chair in atmospheric chemistry and a distinguished professor at the Scripps Institution of Oceanography and department of chemistry and biochemistry at UC San Diego. Her work focuses on how humans are influencing the atmosphere and climate. In 2019, she was elected a member of the National Academy of Engineering for technologies that transformed understanding of aerosols and their impacts on air quality, climate, and human health. In 2020, she was elected as a member of the National Academy of Sciences. She is also an elected Fellow of the American Philosophical Society, American Geophysical Union, the American Association for the Advancement of Science, American Philosophical Society, and the American Academy of Arts and Sciences.
Vicki Wysocki is an American scientist. She is a professor and an Ohio Eminent Scholar at Ohio State University, and also the director of the Campus Chemical Instrument Center.
Nadine Unger is a Professor of Atmospheric Chemistry at the University of Exeter. She has studied the role of human activities and forests on the Earth's climate.
Julia Yvonne Schmale is a German environmental scientist. She is a specialist in the micro-physical makeup of the atmosphere, in particular aerosols and their interaction with clouds. She is a professor at EPFL and the head of the Extreme Environments Research Laboratory (EERL). She is a participant in the Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) expeditions.
Julia Laskin is the William F. and Patty J. Miller Professor of Analytical Chemistry at Purdue University. Her research is focused on the fundamental understanding of ion-surface collisions, understanding of phenomena underlying chemical analysis of large molecules in complex heterogeneous environments, and the development of new instrumentation and methods in preparative and imaging mass spectrometry.
Hilkka Inkeri Kenttämaa is a researcher in organic and bioorganic mass spectrometry, and the Frank Brown Endowed Distinguished Professor of Chemistry at Purdue University. She is a pioneer in distonic radical cation research and laser-induced acoustic desorption.
Hugh Coe is a British atmospheric physicist, currently Head of Atmospheric Sciences and Professor of Atmospheric Composition at the University of Manchester. His research investigates the physics and chemistry of atmospheric aerosols, including their role in climate change and air pollution.
Chiara Giorio is an Italian atmospheric chemist who is an Assistant Professor in the Yusuf Hamied Department of Chemistry at the University of Cambridge, a Fellow of Christ's College and a Fellow of the Community for Analytical Measurement Science.