Jermain Taylor is an American former professional boxer who competed from 2001 to 2014. He remains the most recent undisputed middleweight champion, having won the WBA (Undisputed), WBC, IBF, WBO, and The Ring middleweight titles in 2005 by beating Bernard Hopkins, and in doing so ending Hopkins' ten-year reign as middleweight champion. This made Taylor the first, and to date, only male boxer in history to claim each title from all four major boxing sanctioning organizations in a single fight. He once again defeated Hopkins six months later, making him the only fighter to have defeated Hopkins twice. He retired as a world champion in the months that followed his capture of the IBF middleweight title for a second time, after making a substantial recovery from a brain injury sustained earlier in his career.
Glengoffe Donovan Bartholomew Johnson is a Jamaican former professional boxer who competed from 1993 to 2015. He held the IBF, IBO and Ring magazine light heavyweight titles between 2004 and 2005, and challenged once each for world titles at middleweight and super middleweight.
Howard Anthony Eastman is a Guyanese-British former professional boxer who competed from 1994 to 2014. He challenged twice for middleweight world championships; the vacant WBA title in 2001; and the undisputed title against Bernard Hopkins in 2005. At regional level, he held the British, Commonwealth and EBU European middleweight titles twice each between 1998 and 2007.
Edison Miranda is a Colombian former professional boxer who competed from 2001 to 2021. He challenged once each for the IBF middleweight and super middleweight world titles, and was considered to be one of the most dangerous contenders at middleweight due to his exceptionally high knockout-to-win percentage.
Lucian Bute is a Romanian-Canadian former professional boxer who competed from 2003 to 2017. He held the IBF super-middleweight title from 2007 to 2012, successfully making nine consecutive defenses and reaching a peak ranking of number one in the division by The Ring magazine.
Avetik Abrahamyan, best known as Arthur Abraham, is an Armenian-German former professional boxer who competed from 2003 to 2018. He held multiple world championships in two weight classes, including the IBF middleweight title from 2005 to 2009, and the WBO super-middleweight title twice between 2012 and 2016.
Silvio Branco is an Italian former professional boxer of Romani origin.
Andre Dirrell is an American professional boxer who held the IBF interim super middleweight title from 2017 to 2018. As an amateur, he won a bronze medal in the middleweight division at the 2004 Olympics. His younger brother Anthony Dirrell is also a professional boxer.
Raúl Márquez is an American former professional boxer who competed from 1992 to 2008. He held IBF junior middleweight title between April and December 1997. Márquez also represented the U.S. at the 1992 Summer Olympics in Barcelona.
Verno Jeremias Phillips is a Belizean former professional boxer who competed from 1988 to 2008. He is a three-time junior middleweight world champion, having held the WBO title from 1993 to 1995, and the IBF title twice in 2004 and 2008.
Carl Martin Froch, is a British former professional boxer who competed from 2002 to 2014, and has since worked as a boxing analyst and commentator. He held multiple super-middleweight world championships, including the World Boxing Council (WBC) title twice between 2008 and 2011, the International Boxing Federation (IBF) title from 2012 to 2015, and the World Boxing Association (WBA) title between 2013 and 2015. At regional level, he held the British and Commonwealth super-middleweight titles between 2004 and 2008, and won the Lonsdale Belt in 2006. As an amateur, in the middleweight division, Froch won a bronze medal at the 2001 World Championships, and the ABA title twice.
Anthony Lavar Hanshaw is an American professional boxer from 2000 to 2013. As an amateur, he won the 1998 National Golden Gloves at welterweight.
Antwun Echols was an American boxer who was a world middleweight contender throughout the late 1990s and early 2000s. His hometown was Davenport, Iowa.
Khoren Gevor is an Armenian-German professional boxer. He held the European middleweight title from 2008 to 2009, and challenged four times for a world title at middleweight and super-middleweight.
Sébastien Demers is a Canadian former professional boxer who competed from 2004 to 2013 and challenged for the IBF middleweight title in 2007.
Sergey Shtikhlits, best known as Robert Stieglitz, is a German former professional boxer who competed from 2001 to 2017. He held the WBO super-middleweight title twice between 2009 and 2014, and the European light-heavyweight title from 2016 to 2017.
Kofi Jantuah is a Ghanaian professional boxer that fights at middleweight. He was born in Kumasi, Ghana and now lives in Las Vegas.
Nikola Stevanović is a Serbian professional boxer and a former IBF Intercontinental light middleweight champion.
José Uzcátegui is a Venezuelan professional boxer who held the IBF super middleweight title from 2018 to 2019.
Michael Zerafa is an Australian professional boxer. He held the Commonwealth light middleweight title in 2018.
Zane Marks
Mark Woolnough
Arthur Abraham 
Marcos Primera
Rene Arostegui
Errol Banner