LMAN2

LMAN2
Identifiers
Aliases	LMAN2 , C5orf8, GP36B, VIP36, lectin, mannose binding 2
External IDs	OMIM: 609551; MGI: 1914140; HomoloGene: 4962; GeneCards: LMAN2; OMA:LMAN2 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5q35.3 Start 177,315,805 bp [1] End 177,351,840 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13|13 B1 Start 55,491,646 bp [2] End 55,510,596 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium body of pancreas right lobe of liver mucosa of esophagus granulocyte gallbladder mucosa of transverse colon right lobe of thyroid gland monocyte left lobe of thyroid gland Top expressed in spermatid right kidney spermatocyte decidua yolk sac proximal tubule brown adipose tissue lacrimal gland islet of Langerhans lip More reference expression data BioGPS More reference expression data
Gene ontology Molecular function mannose binding heat shock protein binding metal ion binding carbohydrate binding protein binding Cellular component integral component of membrane cell surface Golgi apparatus integral component of plasma membrane extracellular exosome endoplasmic reticulum-Golgi intermediate compartment membrane endoplasmic reticulum membrane endoplasmic reticulum-Golgi intermediate compartment extracellular space Golgi membrane endoplasmic reticulum membrane COPII-coated ER to Golgi transport vesicle Biological process protein transport positive regulation of phagocytosis retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum transport endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum organization Golgi organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10960 66890 Ensembl ENSG00000169223 ENSMUSG00000021484 UniProt Q12907 Q9DBH5 RefSeq (mRNA) NM_006816 NM_025828 RefSeq (protein) NP_006807 NP_080104 Location (UCSC) Chr 5: 177.32 – 177.35 Mb Chr 13: 55.49 – 55.51 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Vesicular integral-membrane protein VIP36 is a protein that in humans is encoded by the LMAN2 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000169223 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021484 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nufer O, Mitrovic S, Hauri HP (Apr 2003). "Profile-based data base scanning for animal L-type lectins and characterization of VIPL, a novel VIP36-like endoplasmic reticulum protein". J Biol Chem. 278 (18): 15886–96. doi: 10.1074/jbc.M211199200 . PMID   12609988.
6. "Entrez Gene: LMAN2 lectin, mannose-binding 2".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Füllekrug J, Scheiffele P, Simons K (1999). "VIP36 localisation to the early secretory pathway". J. Cell Sci. 112 (17): 2813–21. doi:10.1242/jcs.112.17.2813. PMID   10444376.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID   12754519. S2CID   581283.
• Søborg C, Madsen HO, Andersen AB, et al. (2003). "Mannose-binding lectin polymorphisms in clinical tuberculosis". J. Infect. Dis. 188 (5): 777–82. doi: 10.1086/377183 . PMID   12934195.
• Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. 279 (45): 47242–53. doi: 10.1074/jbc.M406644200 . PMID   15308636.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Nawa D, Shimada O, Kawasaki N, et al. (2007). "Stable interaction of the cargo receptor VIP36 with molecular chaperone BiP". Glycobiology. 17 (9): 913–21. doi:10.1093/glycob/cwm067. PMID   17586539.