LMBR1L

LMBR1L
Identifiers
Aliases	LMBR1L , LIMR, limb development membrane protein 1 like
External IDs	OMIM: 610007; MGI: 1289247; HomoloGene: 10011; GeneCards: LMBR1L; OMA:LMBR1L - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.12 Start 49,097,136 bp [1] End 49,110,900 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15 F1|15 55.1 cM Start 98,801,798 bp [2] End 98,816,112 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis left testis right uterine tube anterior pituitary left ovary gastric mucosa body of uterus tibial nerve right hemisphere of cerebellum right ovary Top expressed in neural layer of retina granulocyte spermatid spermatocyte lip yolk sac seminiferous tubule thymus ventricular zone tail of embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding transmembrane signaling receptor activity Cellular component membrane integral component of membrane plasma membrane integral component of plasma membrane Biological process endocytosis receptor-mediated endocytosis signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55716 74775 Ensembl ENSG00000139636 ENSMUSG00000022999 UniProt Q6UX01 Q9D1E5 RefSeq (mRNA) NM_001300750 NM_001300751 NM_018113 NM_001352161 NM_001352162 NM_001352163 NM_001352164 NM_001352165 NM_001352166 NM_001352167 NM_001352168 NM_029098 RefSeq (protein) NP_001287679 NP_001287680 NP_060583 NP_001339090 NP_001339091 NP_001339092 NP_001339093 NP_001339094 NP_001339095 NP_001339096 NP_001339097 NP_083374 Location (UCSC) Chr 12: 49.1 – 49.11 Mb Chr 15: 98.8 – 98.82 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein LMBR1L is a protein that in humans is encoded by the LMBR1L gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000139636 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022999 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (Jan 2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi: 10.1093/dnares/6.5.329 . PMID   10574461.
6. Wojnar P, Lechner M, Merschak P, Redl B (Jun 2001). "Molecular cloning of a novel lipocalin-1 interacting human cell membrane receptor using phage display". J Biol Chem. 276 (23): 20206–12. doi: 10.1074/jbc.M101762200 . PMID   11287427.
7. "Entrez Gene: LMBR1L limb region 1 homolog (mouse)-like".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Wojnar P, Lechner M, Redl B (2003). "Antisense down-regulation of lipocalin-interacting membrane receptor expression inhibits cellular internalization of lipocalin-1 in human NT2 cells". J. Biol. Chem. 278 (18): 16209–15. doi: 10.1074/jbc.M210922200 . PMID   12591932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Zhang Z, Kim SJ, Chowdhury B, et al. (2006). "Interaction of uteroglobin with lipocalin-1 receptor suppresses cancer cell motility and invasion". Gene. 369: 66–71. doi:10.1016/j.gene.2005.10.027. PMID   16423471.