Lactiplantibacillus plantarum PS128

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Lactiplantibacillus plantarum PS128
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Bacteria
Kingdom: Bacillati
Phylum: Bacillota
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactiplantibacillus
Species: L. plantarum
Strain:L. p. PS128
Trionomial name
Lactiplantibacillus plantarum PS128

Lactiplantibacillus plantarum PS128 is a specific strain of Lactiplantibacillus plantarum , a bacterium of the genus Lactobacillus .

Lactiplantibacillus plantarum is a diverse species of lactic bacterium found in a wide range of ecological niches including plant substrates, meat, milk, as well as in the gastrointestinal tract of humans. Lactic bacteria are gram-positive, oxygen-tolerant anaerobes that have been used in food fermentation for hundreds of years. [1]

Safety

Lactiplantibacillus plantarum is "generally recognized as safe". [2] and included in the "qualified presumption of safety" list of the European Food Safety Authority. [3]

A study on Rett syndrome patients found that probiotic Lactiplantibacillus plantarum PS128 supplementation was safe, well-tolerated, and showed promising improvements in cognitive development and dystonia, suggesting potential as a complementary therapy for Rett syndrome. [4]

References

  1. ↑ Behera, Sudhanshu S.; Ray, Ramesh C.; Zdolec, Nevijo (2018-05-28). "Lactobacillus plantarum with Functional Properties: An Approach to Increase Safety and Shelf-Life of Fermented Foods". BioMed Research International. 2018: 1–18. doi: 10.1155/2018/9361614 . ISSN   2314-6133. PMC   5994577 . PMID   29998137.
  2. ↑ "Generally Recognized as Safe (GRAS)". FDA. 2020-08-04. Archived from the original on May 6, 2019. Retrieved 2020-10-06.
  3. ↑ Koutsoumanis, Kostas; Allende, Ana; Alvarez-Ordóñez, Avelino; Bolton, Declan; Bover-Cid, Sara; Chemaly, Marianne; Davies, Robert; Cesare, Alessandra De; Hilbert, Friederike; Lindqvist, Roland; Nauta, Maarten (2020). "Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 12: suitability of taxonomic units notified to EFSA until March 2020". EFSA Journal. 18 (7): e06174. doi:10.2903/j.efsa.2020.6174. ISSN   1831-4732. PMC   7331632 . PMID   32760463.
  4. ↑ Wong, Lee Chin; Hsu, Chia-Jui; Wu, Yen-Tzu; Chu, Hsu-Feng; Lin, Jui-Hsiang; Wang, Hsin-Pei; Hu, Su-Ching; Tsai, Ying-Chieh; Tsai, Wen-Che; Lee, Wang-Tso (September 2024). "Investigating the impact of probiotic on neurological outcomes in Rett syndrome: A randomized, double-blind, and placebo-controlled pilot study" . Autism. 28 (9): 2267–2281. doi:10.1177/13623613231225899. ISSN   1362-3613. PMID   38361371.
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