LAYN | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | LAYN , Layilin | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | MGI: 2685357 HomoloGene: 18716 GeneCards: LAYN | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Layilin is a protein that in humans is encoded by the LAYN gene. [5]
A study has shown that Layilin is upregulated in tumor infiltrating CD8+ Cytotoxic T cells of patients with liver cancer. [6]
The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) or TGR5 as is a protein that in humans is encoded by the GPBAR1 gene.
Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the ARHGAP1 gene.
Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene.
N-ethylmaleimide-sensitive factor Attachment Protein Alpha, also known as SNAP-α, is a SNAP protein that is involved in the intra-cellular trafficking and fusing of vesicles to target membranes in cells.
Protein tyrosine phosphatase type IVA 3 is an enzyme that in humans is encoded by the PTP4A3 gene.
Hyaluronan-mediated motility receptor (HMMR), also known as RHAMM (Receptor for Hyaluronan Mediated Motility) is a protein which in humans is encoded by the HMMR gene. RHAMM recently has been also designated CD168 (cluster of differentiation 168).
Hyaluronan synthase 2 is an enzyme that in humans is encoded by the HAS2 gene.
Serine/threonine-protein kinase D2 or PKD2 is an enzyme that in humans is encoded by the PRKD2 gene.
Hyaluronan synthase 1 is an enzyme that in humans is encoded by the HAS1 gene.
Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1), also known as extracellular link domain containing 1 (XLKD1) is a Link domain-containing hyaladherin, a protein capable of binding to hyaluronic acid (HA), homologous to CD44, the main HA receptor. In humans it is encoded by the LYVE1 gene.
Stabilin-1 is a protein that in humans is encoded by the STAB1 gene.
Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene.
Type-1 angiotensin II receptor-associated protein is a protein that in humans is encoded by the AGTRAP gene.
Derlin-2 is a protein that in humans is encoded by the DERL2 gene.
Kinesin-like protein KIFC3 is a protein that in humans is encoded by the KIFC3 gene.
Stabilin-2 is a protein that in humans is encoded by the STAB2 gene.
Talin-1 is a protein that in humans is encoded by the TLN1 gene. Talin-1 is ubiquitously expressed, and is localized to costamere structures in cardiac and skeletal muscle cells, and to focal adhesions in smooth muscle and non-muscle cells. Talin-1 functions to mediate cell-cell adhesion via the linkage of integrins to the actin cytoskeleton and in the activation of integrins. Altered expression of talin-1 has been observed in patients with heart failure, however no mutations in TLN1 have been linked with specific diseases.
Talin 2 is a protein in humans that is encoded by the TLN2 gene. It belongs to the talin protein family. This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments. Talin-2 is expressed at high levels in cardiac muscle and functions to provide linkages between the extracellular matrix and actin cytoskeleton at costamere structures to transduce force laterally.
Calcium/calmodulin dependent protein kinase II inhibitor 1 is a protein that in humans is encoded by the CAMK2N1 gene.
Asialoglycoprotein receptor 1 is a protein that in humans is encoded by the ASGR1 gene.