Linda Richards (neuroscientist)

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Linda Jane Richards
Linda Richards, 2017.jpg
Linda Richards in 2017
Born
Australia
CitizenshipAustralian
Alma mater University of Melbourne,
Walter and Eliza Hall Institute
Scientific career
FieldsNeuroscience
InstitutionsWashington University School of Medicine
Doctoral advisor Perry Bartlett

Linda Jane Richards is an Australian developmental neurobiologist, and is currently head of the Department of Neuroscience and the Edison Professor of Neurobiology at Washington University (St. Louis, MO, USA). [1] She was appointed as an Officer of the Order of Australia (AO) in 2019, Fellow of the Australian Academy of Health and Medical Sciences (FAHMS) in 2016, and Fellow of the Australian Academy of Science (FAAS) in 2015. [2]

Contents

Richards is known for her work on the corpus callosum, the bundle of nerves that connects the left and right hemispheres of the brain. She is a founding member of International Consortium for the Corpus Callosum and Cerebral Connectivity (IRC5), [3] a past president of the Australasian Neuroscience Society, [4] and the founder of the Australian Brain Bee Championship. [5]

Early life and education

Richards undertook undergraduate studies at Monash University, and at the University of Melbourne, where she was awarded a Bachelor of Science in 1990. [6] Her PhD ("Regulation of differentiation and lineage determination in the central nervous system," [7] under the supervision of Perry Bartlett), which researched the determination of neuronal lineage of in the developing spinal cord, was conferred in 1995 by the University of Melbourne. [6]

Research and career

Richards began her postdoctoral training at the Salk Institute of Biological Studies, in the laboratory of Professor Dennis O'Leary. In 1997 she established her own laboratory at the University of Maryland medical school. In 2005 she returned to Australia, taking up a position at the University of Queensland, where she was appointed Associate Professor in the Queensland Brain Institute, and the School of Biomedical Sciences. She was subsequently promoted to Professor in 2010. [8]

Richards has been the Chair of the Department of Neuroscience at the Washington University in St. Louis since 2021. [9] Richards is also the head of the Cortical Development and Axon Guidance Laboratory at the QBI. The laboratory researches the cellular and molecular mechanisms which regulate the formation and development of the corpus callosum. The research focus of her laboratory to study the development of the cortical midline in animal models and in human tissue. [10] In particular, she is involved in researching a phenomenon where the corpus callosum is absent (agenesis) or disformed (dysgenesis) in the developing brain. [11] This condition affects 1 in 4000 people, and is associated with 50 different human congenital disorders. [12]

Professional appointments

Awards and honours

Selected publications

Richards has published over 220 articles. Her most cited articles include Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity (2007), [25] Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development (2003), [26] and De novo generation of neuronal cells from the adult mouse brain (1992). [27]

Brain Bee Challenge

In 2006, Richards founded the Australian-New Zealand Brain Bee Challenge. This a competition for secondary students interested in neuroscience. The goal is to educate students and teachers about neuroscience and to encourage students from rural Australia and New Zealand to become involved in neuroscience. [28]

References

  1. Bhandari, Tamara (3 April 2020). "Richards named head of neuroscience". WashU Medicine. Retrieved 19 February 2025.
  2. "OFFICER (AO) IN THE GENERAL DIVISION OF THE ORDER OF AUSTRALIA 2019" (PDF). Retrieved 19 February 2025.
  3. administrator. "Home". IRC5. Retrieved 19 February 2025.
  4. "Home - Australasian Neuroscience Society Inc". www.ans.org.au. Retrieved 19 February 2025.
  5. "Competition – International Brain Bee" . Retrieved 19 February 2025.
  6. 1 2 Centre for Transformative Innovation, Swinburne University of Technology. "Richards, Linda Jane - Person - Encyclopedia of Australian Science and Innovation". www.eoas.info. Retrieved 19 February 2025.
  7. "Trove". trove.nla.gov.au. Retrieved 19 February 2025.
  8. "Professor Linda Richards AO". AusDoCC. Retrieved 19 February 2025.
  9. "Linda Richards". Brain Development and Disorders Laboratory. 21 January 2022. Retrieved 24 July 2024.
  10. "The Richards Lab Cortical Development and Axon Guidance".
  11. Suarez, R (14 July 2014). "Evolution and development of interhemispheric connections in the vertebrate forebrain". Frontiers in Human Neuroscience. 8: 497. doi: 10.3389/fnhum.2014.00497 . PMC   4094842 . PMID   25071525.
  12. "The Corpus Collosum".
  13. "Professor Linda Richards AO". Australian Disorders of the Corpus Callosum.
  14. Adams, Amy; Albin, Stephanie; Amunts, Katrin; Asakawa, Tasia; Bernard, Amy; Bjaalie, Jan G.; Chakli, Khaled; Deshler, James O.; Koninck, Yves De; Ebell, Christoph J.; Egan, Gary; Hale, Melina E.; Häusser, Michael; Jeong, Sung-Jin; Illes, Judy (22 January 2020). "International Brain Initiative: An Innovative Framework for Coordinated Global Brain Research Efforts". Neuron. 105 (2): 212–216. doi:10.1016/j.neuron.2020.01.002. ISSN   0896-6273. PMID   31972144.
  15. "Boards". International Brain Laboratory. Retrieved 20 February 2025.
  16. "Australian Brain Alliance | Brain Alliance Chair Appoints New Executive Committee". Australian Brain Alliance. Retrieved 19 February 2025.
  17. "Million Minds to focus on eating disorders, Indigenous and youth mental health" . Retrieved 20 February 2025.
  18. "Colman Speed Honours Award". WEHI. Retrieved 19 February 2025.
  19. Haines, Duane E. (2004). "AAA award winners". The Anatomical Record Part B: The New Anatomist. 278B (1): 4–7. doi:10.1002/ar.b.20014. ISSN   1552-4914.
  20. "Nina Kondelos Award". Archived from the original on 16 December 2014.
  21. "Equity and Diversity Awards celebrate achievements".
  22. "Linda Richards". www.science.org.au. Retrieved 12 September 2019.
  23. "Fellowship of the Australian Academy of Health and Medical Sciences" (PDF). Australian Academy of Health and Medical Sciences. June 2019. Archived from the original (PDF) on 24 September 2019. Retrieved 12 September 2019.
  24. "Officer of the Order of Australia (AO) entry for Professor Linda Jane RICHARDS". Australian Honours Database. Canberra, Australia: Department of the Prime Minister and Cabinet . Retrieved 8 June 2020. For distinguished service to medical research and education in the field of developmental neurobiology, and to community engagement in science.
  25. Paul, Lynn K.; Brown, Warren S.; Adolphs, Ralph; Tyszka, J. Michael; Richards, Linda J.; Mukherjee, Pratik; Sherr, Elliott H. (2007). "Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity" (PDF). Nature Reviews Neuroscience. 8 (4): 287–299. doi:10.1038/nrn2107. PMID   17375041.
  26. Gu, Chenghua; Rodriguez, E. Rene; Reimert, Dorothy V.; Shu, Tianzhi; Fritzsch, Bernd; Richards, Linda J.; Kolodkin, Alex L.; Ginty, David D. (2003). "Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development". Developmental Cell. 5 (1): 45–57. doi:10.1016/S1534-5807(03)00169-2. PMC   3918747 . PMID   12852851.
  27. Richards, L J; Kilpatrick, T J; Bartlett, P F (15 September 1992). "De novo generation of neuronal cells from the adult mouse brain". Proceedings of the National Academy of Sciences. 89 (18): 8591–8595. Bibcode:1992PNAS...89.8591R. doi: 10.1073/pnas.89.18.8591 . ISSN   0027-8424. PMC   49966 . PMID   1528866.
  28. "Australian Brain Bee Challenge".

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