Lisa Jones (scientist)

Last updated
Lisa Jones
Alma mater Syracuse University
Georgia State University
Known forCell footprinting
Scientific career
Institutions University of California, San Diego
University of Maryland
Indiana University-Purdue University Indianapolis
Washington University
University of Alabama at Birmingham
Thesis Using Protein Design to Understand the Role of Electrostatic Interactions on Calcium Binding Affinity and Molecular Recognition  (2008)
Doctoral advisor Jenny J. Yang
Other academic advisors Michael Gross
Website Official website

Lisa Michelle Jones (born February 1977) is a professor of chemistry and biochemistry at the University of California, San Diego (UCSD). [1] Her research is in structural proteomics, using mass spectrometry (MS) together with fast photochemical oxidation of proteins (FPOP), allowing researchers to study the solvent accessibility of proteins experimentally.

Contents

Early life and education

Jones became interested in science as a freshman at high school, where she took part in a national Science Technology Engineering Program. [2] She earned a BS in biochemistry at Syracuse University in 1999. [3] Jones completed her PhD at Georgia State University and specialized in structural biology. [4]

Jones received postdoctoral training in structural virology at the University of Alabama at Birmingham. She was a Pfizer postdoctoral researcher at Washington University in St. Louis working with Michael Gross on MS-based protein footprinting developed by Maleknia and co-workers in the late 1990s. [5] [6] [2] [7]

Research and career

After her postdoctoral research, she joined Indiana University, where she became an associate professor. [8] [9] She moved to the University of Maryland School of Pharmacy in 2016. [10] In her research, Jones focusses on structural proteomics, having developed fast photochemical oxidation of proteins (FPOP) which uses an excimer laser for photolysis, which generates hydroxyl radicals. Hydroxyl radicals go on to oxidise the side chains of amino acids and provide solvent accessibility of proteins within a cell. [11] FPOP can provide information on the sites of ligand binding, protein interaction and protein conformational changes in vivo. More recently, her group has extended the platform with a no-flow platform for high-throughput in-cell measurements. [12]

In 2019, she received the Biophysical Society's Junior Faculty Award. [13]

Jones also works on science outreach and improving representation in the sciences. She is a mentor in the UMD CURE Scholars Program [14] [15] and a member of the American Society for Mass Spectrometry Diversity and Outreach Working Group. [16] Jones is also co-director of the Initiative to Maximize Student Development (IMSD) Meyerhoff Graduate Fellowship Program, a program for increasing representation of minority students in STEM. [17]

In 2021, Jones was in the news for turning down a faculty position at the University of North Carolina Chapel Hill in protest of controversy regarding the tenure status of journalist Nikole Hannah-Jones. [18] [19]

Related Research Articles

<span class="mw-page-title-main">Max Planck Institute of Biochemistry</span> Research institute in Martinsried, Germany

The Max Planck Institute of Biochemistry is a research institute of the Max Planck Society located in Martinsried, a suburb of Munich. The institute was founded in 1973 by the merger of three formerly independent institutes: the Max Planck Institute of Biochemistry, the Max Planck Institute of Protein and Leather Research, and the Max Planck Institute of Cell Chemistry.

<span class="mw-page-title-main">Matthias Mann</span> German physicist and biochemist (born 1959)

Matthias Mann is a German physicist and biochemist. He is doing research in the area of mass spectrometry and proteomics.

<span class="mw-page-title-main">Bayer School of Natural and Environmental Sciences</span>

The Bayer School of Natural and Environmental Sciences (BSNES) is a fully accredited degree-granting institution and the primary college of undergraduate and graduate scientific research at Duquesne University in Pittsburgh, Pennsylvania. It was formed in 1994 with the separation of the Biological Sciences, Chemistry, and Biochemistry departments from the former College of Liberal Arts and Sciences, and subsequently named in honor of the Bayer Corporation. The school currently houses the departments of Biological Sciences, Biotechnology, Biochemistry, Chemistry, Environmental Science & Management, Forensic Science & Law, and Physics. The school also collaborates closely with the Duquesne University School of Pharmacy. In 2010, the department of Chemistry and Biochemistry was designated as a Mass Spectrometry Center of Excellence by Agilent Technologies, allowing for collaborative research into metabolics, proteomics, disease biomarkers, and environmental analysis. In 2011, Duquesne University became one of 98 universities nationwide, and one of nine Catholic universities, to be designated as a high research activity institution by the Carnegie Foundation.

<span class="mw-page-title-main">David E. Clemmer</span> American chemist

David E. Clemmer is an analytical chemist and the Distinguished Professor and Robert and Marjorie Mann Chair of Chemistry at Indiana University in Bloomington, Indiana, where he leads the Clemmer Group. Clemmer develops new scientific instruments for ion mobility mass spectrometry (IMS/MS), including the first instrument for nested ion-mobility time-of-flight mass spectrometry. He has received a number of awards, including the Biemann Medal in 2006 "for his pioneering contributions to the integration of ion mobility separations with a variety of mass spectrometry technologies."

Michael L. Gross is Professor of Chemistry, Medicine, and Immunology, at Washington University in St. Louis. He was formerly Professor of Chemistry at the University of Nebraska-Lincoln from 1968–1994. He is recognized for his contributions to the field of mass spectrometry and ion chemistry. He is credited with the discovery of distonic ions, chemical species containing a radical and an ionic site on different atoms of the same molecule.

<span class="mw-page-title-main">Carol V. Robinson</span> British chemist and professor

Dame Carol Vivien Robinson is a British chemist and former president of the Royal Society of Chemistry (2018–2020). She was a Royal Society Research Professor and is the Dr Lee's Professor of Physical and Theoretical Chemistry, and a professorial fellow at Exeter College, University of Oxford. She is the founding director of the Kavli Institute for Nanoscience Discovery, University of Oxford, and she was previously professor of mass spectrometry at the chemistry department of the University of Cambridge.

Kevin Downard is a British - Australian academic scientist whose research specialises in the improving responses to infectious disease through the application and development of mass spectrometry and other molecular approaches in the life and medical sciences. Downard has over 35 years of experience in the field and has written 150 lead-author scientific peer-reviewed journal publications, and two books including a textbook for the Royal Society of Chemistry and the first book to be published on the role of mass spectrometry in the study of protein interactions.

<span class="mw-page-title-main">Albert J. R. Heck</span> Dutch chemist

Albert J.R. Heck is a Dutch scientist and professor at Utrecht University, the Netherlands in the field of mass spectrometry and proteomics. He is known for his work on technologies to study proteins in their natural environment, with the aim to understand their biological function. Albert Heck was awarded the Spinoza Prize in 2017, the highest scientific award in the Netherlands.

Natalie G. Ahn is a professor of chemistry and biochemistry at the University of Colorado at Boulder. Her research is focused on understanding the mechanisms of cell signaling, with a speciality in phosphorylation and cancers. Ahn's work uses the tools of "classical chemistry" to work on understanding the genetic code and how genetics affects life processes. She has been a professor at the University of Colorado at Boulder since 2003, where she is a distinguished professor. She was a Howard Hughes Medical Institute investigator between 1994 and 2014. In 2018, she was elected to the National Academy of Sciences and named a fellow of the American Academy of Arts and Sciences.

<span class="mw-page-title-main">Catherine Clarke Fenselau</span> American scientist

Catherine Clarke Fenselau is an American scientist who was the first trained mass spectrometrist on the faculty of an American medical school; she joined Johns Hopkins School of Medicine in 1968. She specializes in biomedical applications of mass spectrometry. She has been recognized as an outstanding scientist in the field of bioanalytical chemistry because of her work using mass spectrometry to study biomolecules.

Sheena Elizabeth Radford is a British biophysicist, and Astbury Professor of Biophysics and a Royal Society Research Professor in the Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology at the University of Leeds. Radford is the Associate Editor of the Journal of Molecular Biology.

Renã A. S. Robinson is an associate professor and the Dorothy J. Wingfield Phillips Chancellor's Faculty Fellow in the department of chemistry at the Vanderbilt University, where she is the principal investigator of the RASR Laboratory.

Peter Nemes is a Hungarian-American chemist, who is active in the fields of bioanalytical chemistry, mass spectrometry, cell/developmental biology, neuroscience, and biochemistry.

Ryan Julian is an American chemist and Professor at the University of California, Riverside. His research uses mass spectrometry to study proteins and protein structure. His work has resulted in over 85 publications and he has been recognized with numerous honors including the American Society for Mass Spectrometry Biemann Medal in 2017.

<span class="mw-page-title-main">Claire E. Eyers</span> British biological mass spectrometrist

Claire Eyers is a British biological mass spectrometrist who is professor of biological mass spectrometry at the University of Liverpool, where she heads up the Centre for Proteome Research. Her research publications list her either as Claire E Haydon or Claire E Eyers.

Olga Vitek is a biostatistician and computer scientist specializing in bioinformatics, proteomics, mass spectrometry, causal inference of biological function, and the development of open-source software for statistical analysis in these areas. She is a professor in the College of Science and Khoury College of Computer Sciences of Northeastern University.

Catherine E. Costello is the William Fairfield Warren distinguished professor in the department of biochemistry, Cell Biology and Genomics, and the director of the Center for Biomedical Mass Spectrometry at the Boston University School of Medicine.

Juri Rappsilber is a German chemist in the area of mass spectrometry and proteomics.

Lingjun Li is a Professor in the School of Pharmacy and Department of Chemistry at University of Wisconsin-Madison. She develops mass spectrometry based tools to study neuropeptides, peptide hormones and neurotransmitters.

<span class="mw-page-title-main">Paola Picotti</span> Italian biologist and academic

Paola Picotti is an Italian biochemist who is Professor for Molecular Systems Biology at ETH Zürich. She is Deputy Head of the Institute for Molecular Systems Biology. Her research investigates how the conformational changes of proteins impact molecular networks with cells. She received numerous awarded awards, among which the 2019 EMBO Gold Medal.

References

  1. ↑ "Lisa Jones" . Retrieved 19 August 2024.
  2. 1 2 "IUPUI chemist receives $1.1M NSF grant for research, training of minority future researchers: Newscenter: Indiana University–Purdue University Indianapolis". archive.news.iupui.edu. Retrieved 2018-04-22.
  3. ↑ @Victoria08Davis, VICTORIA T. DAVIS. "IUPUI chemist awarded more than $1 million for research, training of minority students". Indianapolis Recorder Newspaper. Retrieved 2018-04-22.{{cite news}}: CS1 maint: numeric names: authors list (link)
  4. ↑ Jones, Lisa Michelle (4 August 2008). Using Protein Design to Understand the Role of Electrostatic Interactions on Calcium Binding Affinity and Molecular Recognition (PhD). Atlanta, GA: Georgia State University . Retrieved 7 July 2021.
  5. ↑ "SoCal MS: Mass Spec Symposium". SoCal MS. Retrieved 7 July 2021.
  6. ↑ Maleknia, Simin D.; Ralston, Corie Y.; Brenowitz, Michael D.; Downard, Kevin M.; Chance, Mark R. (2001). "Determination of macromolecular folding and structure by synchrotron x‐ray radiolysis techniques". Analytical Biochemistry. 289: 103–115. doi:10.1006/abio.2000.4910. PMID   11161303.
  7. ↑ Jones, Lisa M.; Zhang, Hao; Vidavsky, Ilan; Gross, Michael L. (2010-02-15). "An On-Line, High-Pressure Digestion System for Protein Characterization by Hydrogen/Deuterium Exchange and Mass Spectrometry". Analytical Chemistry. 82 (4): 1171–1174. doi:10.1021/ac902477u. PMC   2826105 . PMID   20095571.
  8. ↑ "Lisa Jones". stem.indiana.edu. Retrieved 2018-04-22.
  9. ↑ Brown, Alex. "IUPUI Professor Receives Lucrative Award" . Retrieved 2018-04-22.
  10. ↑ "Its official! We're getting FPOP in Baltimore!". proteomicsnews.blogspot.co.uk. 2016-06-11. Retrieved 2018-04-22.
  11. ↑ "Professor Lisa Jones - Indiana University" (PDF). University of Toledo. 2014-09-24. Retrieved 2018-04-22.
  12. ↑ "Proteomic Mass Spec Assesses Biomolecular Teamwork". Genetic Engineering and Biotechnology News. 2020-05-04. Retrieved 2020-06-12.
  13. ↑ "PSC Researcher Awarded Biophysical Society's Junior Faculty Award". University of Maryland School of Pharmacy. 2019-03-06. Retrieved 2020-06-12.
  14. ↑ Koch, Denise (July 11, 2017). "UMB's CURE Scholars Program Helps Inner City Kids Get Interested In Science". WJZ CBS Baltimore.
  15. ↑ Fanning, Patricia (July 14, 2017). "Science Beckons CURE Scholars in Summer". University of Maryland, Baltimore. Retrieved 2021-02-27.
  16. ↑ Reid, Gavin E. (September 2017). "American Society for Mass Spectrometry News and Views" (PDF).
  17. ↑ 2016-2017 Annual Report (Report). University of Maryland School of Pharmacy. 2017. p. 40. Retrieved 2021-02-27.
  18. ↑ Newsome, Melba (June 7, 2021). "Chemist Lisa Jones withdraws from UNC faculty search over Pulitzer-winning journalist's tenure denial". Chemical & Engineering News . Retrieved 7 July 2021.
  19. ↑ Chapin, Josh (5 June 2021). "Highly sought-after chemist turns down job at UNC-CH as Hannah-Jones tenure dispute unfolds". WTVD . Retrieved 7 July 2021.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.