This is a list of Maine Black Bears football players in the NFL draft.
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| Year | Round | Pick | Player | Team | Position |
|---|---|---|---|---|---|
| 1956 | 16 | 193 | Thurlow Cooper | Cleveland Browns | E |
| 1959 | 14 | 166 | Roger Ellis | New York Giants | C |
| 1962 | 18 | 242 | Dave Cloutier | Dallas Cowboys | B |
| 1967 | 5 | 113 | John Huard | Denver Broncos | LB |
| 1970 | 11 | 281 | Gene Benner | Cleveland Browns | WR |
| 1980 | 12 | 316 | Roger Lapham | Buffalo Bills | TE |
| 1983 | 12 | 331 | Lorenzo Bouier | Dallas Cowboys | RB |
| 1988 | 6 | 160 | Rob Sterling | Philadelphia Eagles | DB |
| 1990 | 6 | 156 | Mike Buck | New Orleans Saints | QB |
| 7 | 183 | Scott Hough | New Orleans Saints | G | |
| 11 | 293 | Justin Strzelczyk | Pittsburgh Steelers | T | |
| 2006 | 7 | 255 | Kevin McMahan | Oakland Raiders | WR |
| 2007 | 6 | 203 | Daren Stone | Atlanta Falcons | DB |
| 2012 | 4 | 133 | Jerron McMillian | Green Bay Packers | DB |
| 2014 | 6 | 148 | Kendall James | Minnesota Vikings | DB |
| 2016 | 7 | 239 | Trevor Bates | Indianapolis Colts | LB |
| 2018 | 6 | 192 | Jamil Demby | Los Angeles Rams | T |
Note: No drafts held before 1920
| Debut year | Player name | Position | Debut NFL/AFL team | Notes |
|---|---|---|---|---|
| 1962 | Manch Wheeler | QB | Buffalo Bills | — |
| 1979 | Chris Keating | LB | Buffalo Bills | — |
| 1984 | Clay Pickering | WR | Cincinnati Bengals | — |
| 1993 | Dan Jones | T | Cincinnati Bengals | — |
| 1997 | Mike Flynn | C | Baltimore Ravens | — |
| 2001 | Phil McGeoghan | WR | Denver Broncos | — |
| 2003 | Stephen Cooper | LB | San Diego Chargers | — |
| 2005 | Brandon McGowan | S | Chicago Bears | — |
| 2006 | Montell Owens | FB | Jacksonville Jaguars | — |
| 2007 | Mike DeVito | DE | New York Jets | — |
| 2008 | Matthew Mulligan | TE | Miami Dolphins | — |
| 2009 | Jovan Belcher | LB | Kansas City Chiefs | — |
| 2014 | Justin Perillo | TE | Green Bay Packers | — |
| 2017 | Patrick Ricard | FB | Baltimore Ravens | — |
| 2023 | Zavier Scott | RB | Indianapolis Colts | — |