This is a list of Murray State Racers football players in the NFL draft.
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| Year | Round | Pick | Overall | Player | Team | Position |
|---|---|---|---|---|---|---|
| 1941 | 13 | 4 | 114 | Bill McMurray | Cleveland Rams | E |
| 18 | 4 | 164 | Cobbie Lee | Cleveland Rams | B | |
| 1942 | 18 | 5 | 165 | George Speth | Detroit Lions | T |
| 1944 | 8 | 7 | 72 | Cliff White | Washington Redskins | T |
| 1950 | 20 | 12 | 260 | John Hackney | Cleveland Browns | G |
| 1952 | 20 | 8 | 237 | Gil Mains | Detroit Lions | T |
| 1954 | 29 | 10 | 347 | Ted Dunn | San Francisco 49ers | B |
| 1957 | 17 | 11 | 204 | Don Heine | Chicago Bears | E |
| 1958 | 19 | 12 | 229 | Dave Bottos | Detroit Lions | B |
| 1962 | 19 | 8 | 260 | Bob Burton | San Francisco 49ers | T |
| 1973 | 16 | 22 | 412 | George Greenfield | Cleveland Browns | RB |
| 1975 | 15 | 14 | 378 | Don Clayton | New England Patriots | RB |
| 1983 | 10 | 1 | 252 | Ronald Hopkins | Baltimore Colts | DB |
| 1985 | 6 | 14 | 154 | Keith Lester | Cincinnati Bengals | TE |
| 1988 | 11 | 3 | 280 | Paul Hickert | Cincinnati Bengals | K |
| 1990 | 10 | 13 | 261 | Eric Crigler | Cincinnati Bengals | T |
| 1997 | 6 | 8 | 171 | Mike Cherry | New York Giants | QB |
| 2010 | 5 | 22 | 153 | Austen Lane | Jacksonville Jaguars | DE |
| 2014 | 6 | 20 | 196 | Walt Powell | Arizona Cardinals | WR |
| 2019 | 3 | 34 | 98 | Quincy Williams | Jacksonville Jaguars | LB |
Note: No drafts held before 1936
| Debut year | Player name | Position | Debut NFL/AFL team | Notes |
|---|---|---|---|---|
| 1939 | Claude C. McRaven | WB/DB | Cleveland Rams | — |
| 1940 | Pete Gudauskas † | G | Cleveland Rams | NFL Champion (1943) |
| 1985 | Dan Coleman | DE | Washington Redskins | — |
| 1986 | Jim Yarbrough | DB | Denver Broncos | — |
| 1990 | Michael Proctor | QB | New England Patriots | — |
| 1993 | Melvin Aldridge | LB/DB | Houston Oilers | — |
| 1996 | Derrick Cullors | RB | New England Patriots | — |
| 1998 | Reggie Swinton | WR/RS | Jacksonville Jaguars | — |
| 2003 | Shane Andrus | PK | Indianapolis Colts | — |
| 2005 | Laroni Gallishaw | DB | Minnesota Vikings | — |
| 2008 | Rod Harper † | WR | Green Bay Packers | Super Bowl Champion (XLIV) |
| 2010 | Derrick Townsel | WR | Jacksonville Jaguars | — |
| 2011 | Marcus Harris | WR | Detroit Lions | — |
| 2019 | Drew Anderson | QB | Arizona Cardinals | — |