This article needs additional citations for verification .(December 2020) |
Ibuprofen , an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen. [2] [3] [4] [5] [6]
Name | Available forms | Available strengths | Countries |
---|---|---|---|
Act-3 | |||
Actiprofen | Canada [3] | ||
Actron | Argentina, Uruguay, Chile | ||
Adagin | Romania | ||
Addaprin | USA [3] | ||
Adex | Israel | ||
Advifen | Uganda, Afghanistan, Iraq | ||
Advil | Tablets, Capsules, Liquid, liquid filled capsules | 100 mg, 200 mg | Australia, Brazil, Canada, [3] Colombia, France, Greece, Hungary, Israel, North Macedonia, Mexico, Netherlands, Philippines, South Africa, South Korea, Turkey, USA, [3] Romania |
A-G Profen | USA [3] | ||
Aktren | Austria, Germany | ||
Alaxan | Capsule | Philippines | |
Alges-X | Switzerland | ||
Algifor | Switzerland | ||
Algoflex | Hungary | ||
Algofren | Greece | ||
Alivium | Brazil | ||
Alvofen Express | Capsule | 400 mg | Iceland |
Arinac | Pakistan | ||
Arthrofen | Tablet | 200 mg, 400 mg, 600 mg | UK [1] |
Artofen | Israel | ||
Betagesic | South Africa | ||
Betaprofen | South Africa | ||
Blokmax | North Macedonia, Croatia, Serbia | ||
Bonifen | North Macedonia, Slovenia | ||
Brufen | Tablet, caplet, oral syrup, miscible granules | tablet: 200 mg, 400 mg, 600 mg syrup: 100 mg/5 mL granules: 600 mg/sachet | Austria, Egypt, Greece, India, Italy, New Zealand, Pakistan, Portugal, Saudi Arabia, Serbia, Slovakia, South Africa, South Korea, UK, [1] Romania |
Brufen Retard [7] | Sustained-release film-coated caplet | 800 mg | UK, [1] Poland, Norway [8] |
Bufen | USA [3] | ||
Bugesic | Australia | ||
Buplex [9] | Ireland | ||
Buprovil | Brazil | ||
Burana | Finland, Norway [8] | ||
Caldolor | USA | ||
Calprofen | Oral syrup | 100 mg/5 mL | UK [1] |
Cap-Profen | USA [3] | ||
Combiflam | India [10] [11] | ||
Dalsy [12] | Bosnia and Herzegovina, Brazil, Croatia, Spain | ||
Dismenol | Austria | ||
Diverin | North Macedonia, Slovenia | ||
Dolgit | Austria, Czech Republic, Germany, Hungary, Slovakia, Turkey | ||
Dolofort | Austria | ||
Doloraz | Jordan | ||
Dolormin | Germany | ||
Dolo-Spedifen | Switzerland | ||
Dorival | |||
Easofen [13] | Ireland | ||
Ebufac | Tablet | 200 mg, 400 mg, 600 mg | UK [1] |
EmuProfen | USA | ||
Espidifen | Spain | ||
Eve | Japan | ||
Faspic | Tablet | 200 mg, 400 mg | Philippines |
Fenbid | Topical gel | 10% | China, UK [1] |
Fenpaed | Oral liquid | 20 mg/mL | UK, New Zealand [14] |
Feverfen | Oral liquid | 100 mg/5 mL | UK [1] |
Finalflex | Slovenia | ||
Galprofen | UK[ citation needed ] | ||
Gelofen | Iran | ||
Genpril | USA [3] | ||
Haltran | USA [3] | ||
Hedafen | Tablet | 200 mg | Australia |
Hedex | Kenya, Uganda | ||
Herron Blue | Australia | ||
I-Prin | USA [3] | ||
i-profen | New Zealand | ||
Ibalgin | Czech Republic, Slovakia, Romania | ||
Ibetin | Tablets | 400 mg | Iceland |
Ibrofen | Thailand | ||
Ibu or IBU | Chile, USA [3] | ||
IBUFEN | Israel | ||
Ibugan | Thailand | ||
Ibugel | Topical gel | 10% | UK [1] |
Ibuflam | Suspension | 2%, 4% | Germany, South Africa |
Ibugesic | Latvia | ||
IbuHEXAL | Germany | ||
Ibuleve | Topical gel | Israel, UK | |
Ibum | Poland | ||
Ibumax | Finland, South Africa | ||
Ibumetin | Austria, Denmark, Finland, Latvia, Sweden, Norway [8] | ||
Ibumidol | Uruguay | ||
Ibupain | South Africa | ||
Ibupirac | Argentina, Uruguay | ||
Ibuprofen | Tablet, caplet, oral liquid, topical gel | tablet: 200 mg, 400 mg, 600 mg, 800 mg caplet: ? oral liquid: 100 mg/5 mL topical gel: 5% | UK, [1] Canada, [3] Norway, Romania, [8] USA, [3] Belgium; Netherlands, Czech Republic, Slovakia, Spain, Sweden, Poland |
Ibuprofene | Italy | ||
Ibuprohm | USA [3] | ||
Ibuprom | Poland, Italy, Spain, Portugal, Bulgaria, Russia | ||
Ibuprox | Norway [8] | ||
Ibuprosyn | Finland | ||
IBU-Ratiopharm | Germany | ||
Ibustar | Latvia | ||
Ibutabs | Finland, Slovakia | ||
Ibu-Tab | USA [3] | ||
Ibu-Vivimed | Germany | ||
Ibux | Norway [8] | ||
Ibuxin | Finland | ||
Ibuxin Rapid | Tablets | 400 mg | Iceland |
Inflanor | Suspension | 4% | Czech Republic |
Ipren | Denmark, Sweden | ||
Irfen | Switzerland | ||
Íbúfen | Tablets | 200 mg, 400 mg, 600 mg (Rx only) | Iceland |
Kratalgin | Austria | ||
Lotem | South Africa | ||
Medicol | Philippines | ||
Midol | Liquid Gels | 200 mg | USA [3] |
Moment | Italy | ||
Motrin | tablets, chewable tablets, oral suspension. | 50 mg, 100 mg, 200 mg | Canada, [3] North Macedonia, USA [3] |
Mypaid | South Africa | ||
Myprodol | South Africa | ||
Narfen | South Korea | ||
Naron Ace | Japan | ||
Neobrufen | Spain | ||
Neofen | Croatia | ||
Neupren | Tablet | 200 mg, 400 mg, 600 mg | Algeria |
Norvectan | Spain | ||
Nuprin | Canada, USA [3] | ||
Nureflex | Austria | ||
Nurofen | Tablet, caplet, oral liquid, topical gel [4] [15] | tablet: 200 mg oral liquid: 100 mg/5 mL | Australia, Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, France, Germany, Greece, Hungary, Ireland, Israel, Italy, North Macedonia, Netherlands, New Zealand, Poland, Portugal, Romania, Russia, Serbia, Slovakia, South Africa, Spain, Switzerland, Turkey, UK [1] [4] [15] |
Orbifen | Oral liquid | 100 mg/5 mL | UK [1] |
Paduden | Romania | ||
Panafen | Australia | ||
Paraped Plus | India | ||
Perifar | Uruguay | ||
Profin | Iraq | ||
Proprinal | USA [3] | ||
Proris | Oral liquid, tablet, suppositoria | Indonesia | |
Q-Profen | USA [3] | ||
Ranfen | South Africa | ||
Rapidol | Croatia | ||
Ratiodolor | Austria | ||
Rimafen | Tablet | 200 mg, 400 mg, 600 mg | UK [1] |
Salvarina | Spain | ||
Sarixell | Netherlands | ||
Solpaflex | Slovenia | ||
Spedifen | France, Indonesia | ||
Speedpain NANO | South Korea | ||
Spidifen | Belgium, Portugal | ||
Tefin | Ireland | ||
Unafen | India | ||
Upfen | North Macedonia | ||
Xydol | Tablet | 200 mg, 400 mg, 600 mg | Algeria |
Hydrocodone, also known as dihydrocodeinone, is a semi-synthetic opioid used to treat pain and as a cough suppressant. It is taken by mouth. Typically it is dispensed as the combination acetaminophen/hydrocodone or ibuprofen/hydrocodone for pain severe enough to require an opioid and in combination with homatropine methylbromide to relieve cough. It is also available by itself in a long-acting form sold under the brand name Zohydro ER, among others, to treat severe pain of a prolonged duration. Hydrocodone is a controlled drug: in the United States a Schedule II Controlled Substance.
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and bleeds, heart attack, and kidney disease.
Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) describes multiple isomers, the term THC usually refers to the delta-9-THC isomer with chemical name (−)-trans-Δ9-tetrahydrocannabinol. It is a colorless oil.
Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, like treatment of low blood pressure. At higher doses, it may produce various additional effects, including psychostimulant, appetite suppressant, and performance-enhancing effects. In relation to this, non-medical use of pseudoephedrine has been encountered. The medication is taken by mouth.
Paracetamol (acetaminophen) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely used over-the-counter medication. Common brand names include Tylenol and Panadol.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis. It may also be used to close a patent ductus arteriosus in a premature baby. It can be taken orally or intravenously. It typically begins working within an hour.
Quetiapine, sold under the brand name Seroquel among others, is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Despite being widely used as a sleep aid, the benefits of such use may not outweigh the risk of undesirable side effects. It is taken orally.
Naproxen, sold under the brand name Aleve among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, and inflammatory diseases such as rheumatoid arthritis, gout and fever. It is taken orally. It is available in immediate and delayed release formulations. Onset of effects is within an hour and lasts for up to twelve hours. Naproxen is also available in salt form, naproxen sodium, which has better solubility when taken orally.
Reckitt Benckiser is a British-Dutch multinational consumer goods company headquartered in Slough, United Kingdom, and Hoofddorp, Netherlands. It is a producer of health, hygiene and nutrition products. The company was formed in 1999 by the merger of British company Reckitt & Colman plc and Dutch company Benckiser N.V.
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process—from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials—to approved vaccine or drug typically takes more than a decade.
Harpic is the brand name of a toilet cleaner launched in the United Kingdom in 1932 by Reckitt and Sons. It is currently available in Africa, the Middle East, South Asia, the Asia-Pacific, Europe, and the Americas. The toilet cleaning products marketed under the brand name include liquids, tablets, wipes, brush systems, toilet rim blocks, and in-cistern blocks.
The University of Nottingham School of Pharmacy was founded in 1925 and is located in the University Park Campus of the university. The school also offers courses at the University's Malaysia campus in Kuala Lumpur with students spending two years in Malaysia and two years in Nottingham The School also offers the first joint Pharmacy course with China, with the Tianjin University of Traditional Chinese Medicine. The current head of The School is Professor Barrie Kellam (2021-).
Crookes Healthcare is a healthcare manufacturer based in Nottingham, England, and a subsidiary of Reckitt. It manufactures some of the best-known health remedies and over-the-counter drugs sold by British pharmacies.
Aticaprant, also known by its developmental codes JNJ-67953964, CERC-501, and LY-2456302, is a κ-opioid receptor (KOR) antagonist which is under development for the treatment of major depressive disorder. A regulatory application for approval of the medication is expected to be submitted by 2025. Aticaprant is taken by mouth.
Indivior is a specialty pharmaceuticals business. Established as a division of Reckitt Benckiser in 1994 and demerged from that company in December 2014, the company has been fined for false marketing claims about the safety of its drug, Suboxone. It is listed on the London Stock Exchange and on the NASDAQ Global Select Market.
Kenneth John Harvey AM is an Australian public health doctor, currently Honorary Adjunct Associate Professor at the Institute for Evidence-Based Healthcare in Bond University. Described by The Age as an "anti-quackery crusader", Harvey is an advocate of evidence-based medicine and a critic of pharmaceutical marketing and unproven diet products. He is the president of Friends of Science in Medicine. In 2017, Harvey was awarded a Member of the Order of Australia (AM) for his "significant service to community health and the pharmaceutical industry”.
Nurofen is a brand name range of pain-relief medication containing ibuprofen made by the British multinational Reckitt. Introduced in 1983, the Nurofen brand was acquired following Reckitt Benckiser's acquisition of Boots healthcare international in 2005 for £1.93 billion, which included Nurofen, Strepsils, and Clearasil. The brand is primarily marketed and sold in the United Kingdom, other parts of Europe, South Africa, Australia and New Zealand. In 2016 it was the biggest selling branded over-the-counter medication sold in Great Britain, with sales of £116.8 million.
Stewart Sanders Adams was an English pharmacist, and bioengineer who was part of a team from Boots which developed the painkiller ibuprofen in 1961. Ibuprofen is now on the World Health Organization's Model List of Essential Medicines and is one of the world's best-selling drugs.
Craig M. Crews is an American scientist at Yale University known for his contributions to chemical biology. He is known for his contributions to the field of induced proximity through his work in creating heterobifunctional molecules that "hijack" cellular processes by inducing the interaction of two proteins inside a living cell. His initial work focused on the discovery of PROteolysis-TArgeting Chimeras (PROTACs) to trigger degradation of disease-causing proteins, a process known as targeted protein degradation (TPD), and he has since developed new versions of -TACs to leverage other cellular processes and protein families to treat disease.
Paul Edward Rolan is an Australian physician, medical researcher, academic, and public health advocate. He specializes in the management of chronic pain and headache, and development of novel treatments.