This article needs additional citations for verification .(December 2020) |
Ibuprofen , an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen. [2] [3] [4] [5] [6]
Name | Available forms | Available strengths | Countries |
---|---|---|---|
Act-3 | |||
Actiprofen | Canada [3] | ||
Actron | Argentina, Uruguay, Chile | ||
Adagin | Romania | ||
Addaprin | USA [3] | ||
Adex | Israel | ||
Advifen | Uganda, Afghanistan, Iraq | ||
Advil | Tablets, Capsules, Liquid, liquid filled capsules | 100 mg, 200 mg | Australia, Brazil, Canada, [3] Colombia, France, Greece, Hungary, Israel, North Macedonia, Mexico, Netherlands, Philippines, South Africa, South Korea, Turkey, USA, [3] Romania |
A-G Profen | USA [3] | ||
Aktren | Austria, Germany | ||
Alaxan | Capsule | Philippines | |
Alges-X | Switzerland | ||
Algifor | Switzerland | ||
Algoflex | Hungary | ||
Algofren | Greece | ||
Alivium | Brazil | ||
Arinac | Pakistan | ||
Arthrofen | Tablet | 200 mg, 400 mg, 600 mg | UK [1] |
Artofen | Israel | ||
Betagesic | South Africa | ||
Betaprofen | South Africa | ||
Blokmax | North Macedonia, Croatia, Serbia | ||
Bonifen | North Macedonia, Slovenia | ||
Brufen | Tablet, caplet, oral syrup, miscible granules | tablet: 200 mg, 400 mg, 600 mg syrup: 100 mg/5 mL granules: 600 mg/sachet | Austria, Egypt, Greece, India, Italy, New Zealand, Pakistan, Portugal, Saudi Arabia, Serbia, Slovakia, South Africa, South Korea, UK, [1] Romania |
Brufen Retard [7] | Sustained-release film-coated caplet | 800 mg | UK, [1] Poland, Norway [8] |
Bufen | USA [3] | ||
Bugesic | Australia | ||
Buplex [9] | Ireland | ||
Buprovil | Brazil | ||
Burana | Finland, Norway [8] | ||
Caldolor | USA | ||
Calprofen | Oral syrup | 100 mg/5 mL | UK [1] |
Cap-Profen | USA [3] | ||
Combiflam | India [10] [11] | ||
Dalsy [12] | Bosnia and Herzegovina, Brazil, Croatia, Spain | ||
Dismenol | Austria | ||
Diverin | North Macedonia, Slovenia | ||
Dolgit | Austria, Czech Republic, Germany, Hungary, Slovakia, Turkey | ||
Dolofort | Austria | ||
Doloraz | Jordan | ||
Dolormin | Germany | ||
Dolo-Spedifen | Switzerland | ||
Dorival | |||
Easofen [13] | Ireland | ||
Ebufac | Tablet | 200 mg, 400 mg, 600 mg | UK [1] |
EmuProfen | USA | ||
Espidifen | Spain | ||
Eve | Japan | ||
Faspic | Tablet | 200 mg, 400 mg | Philippines |
Fenbid | Topical gel | 10% | China, UK [1] |
Fenpaed | Oral liquid | 20 mg/mL | UK, New Zealand [14] |
Feverfen | Oral liquid | 100 mg/5 mL | UK [1] |
Finalflex | Slovenia | ||
Galprofen | UK[ citation needed ] | ||
Gelofen | Iran | ||
Genpril | USA [3] | ||
Haltran | USA [3] | ||
Hedafen | Tablet | 200 mg | Australia |
Hedex | Kenya, Uganda | ||
Herron Blue | Australia | ||
I-Prin | USA [3] | ||
i-profen | New Zealand | ||
Ibalgin | Czech Republic, Slovakia, Romania | ||
Ibrofen | Thailand | ||
Ibu or IBU | Chile, USA [3] | ||
IBUFEN | Israel | ||
Íbúfen | Iceland | ||
Ibugan | Thailand | ||
Ibugel | Topical gel | 10% | UK [1] |
Ibuflam | Germany, South Africa | ||
Ibugesic | Latvia | ||
IbuHEXAL | Germany | ||
Ibuleve | Topical gel | Israel, UK | |
Ibum | Poland | ||
Ibumax | Finland, South Africa | ||
Ibumetin | Austria, Denmark, Finland, Latvia, Sweden, Norway [8] | ||
Ibumidol | Uruguay | ||
Ibupain | South Africa | ||
Ibupirac | Argentina, Uruguay | ||
Ibuprofen | Tablet, caplet, oral liquid, topical gel | tablet: 200 mg, 400 mg, 600 mg, 800 mg caplet: ? oral liquid: 100 mg/5 mL topical gel: 5% | UK, [1] Canada, [3] Norway, Romania, [8] USA, [3] Belgium; Netherlands, Czech Republic, Slovakia, Spain, Sweden, Poland |
Ibuprofene | Italy | ||
Ibuprohm | USA [3] | ||
Ibuprom | Poland, Italy, Spain, Portugal, Bulgaria, Russia | ||
Ibuprox | Norway [8] | ||
Ibuprosyn | Finland | ||
IBU-Ratiopharm | Germany | ||
Ibustar | Latvia | ||
Ibutabs | Finland, Slovakia | ||
Ibu-Tab | USA [3] | ||
Ibu-Vivimed | Germany | ||
Ibux | Norway [8] | ||
Ibuxin | Finland | ||
Ipren | Denmark, Sweden | ||
Irfen | Switzerland | ||
Kratalgin | Austria | ||
Lotem | South Africa | ||
Medicol | Philippines | ||
Midol | Liquid Gels | 200 mg | USA [3] |
Moment | Italy | ||
Motrin | tablets, chewable tablets, oral suspension. | 50 mg, 100 mg, 200 mg | Canada, [3] North Macedonia, USA [3] |
Mypaid | South Africa | ||
Myprodol | South Africa | ||
Narfen | South Korea | ||
Naron Ace | Japan | ||
Neobrufen | Spain | ||
Neofen | Croatia | ||
Neupren | Tablet | 200 mg, 400 mg, 600 mg | Algeria |
Norvectan | Spain | ||
Nuprin | Canada, USA [3] | ||
Nureflex | Austria | ||
Nurofen | Tablet, caplet, oral liquid, topical gel [4] [15] | tablet: 200 mg oral liquid: 100 mg/5 mL | Australia, Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, France, Germany, Greece, Hungary, Ireland, Israel, Italy, North Macedonia, Netherlands, New Zealand, Poland, Portugal, Romania, Russia, Serbia, Slovakia, South Africa, Spain, Switzerland, Turkey, UK [1] [4] [15] |
Orbifen | Oral liquid | 100 mg/5 mL | UK [1] |
Paduden | Romania | ||
Panafen | Australia | ||
Paraped Plus | India | ||
Perifar | Uruguay | ||
Profin | Iraq | ||
Proprinal | USA [3] | ||
Proris | Indonesia | ||
Q-Profen | USA [3] | ||
Ranfen | South Africa | ||
Rapidol | Croatia | ||
Ratiodolor | Austria | ||
Rimafen | Tablet | 200 mg, 400 mg, 600 mg | UK [1] |
Salvarina | Spain | ||
Sarixell | Netherlands | ||
Solpaflex | Slovenia | ||
Spedifen | France | ||
Speedpain NANO | South Korea | ||
Spidifen | Belgium, Portugal | ||
Tefin | Ireland | ||
Unafen | India | ||
Upfen | North Macedonia | ||
Xydol | Tablet | 200 mg, 400 mg, 600 mg | Algeria |
An analgesic drug, also called simply an analgesic, pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects.
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and bleeds, heart attack, and kidney disease.
Pseudoephedrine (PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes. It may be used as a nasal/sinus decongestant, as a stimulant, or as a wakefulness-promoting agent in higher doses.
Paracetamol is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely used over the counter medication and common brand names include Tylenol and Panadol.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis. It may also be used to close a patent ductus arteriosus in a premature baby. It can be used orally or intravenously. It typically begins working within an hour.
Quetiapine, sold under the brand name Seroquel among others, is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Despite being widely used as a sleep aid due to its sedating effect, the benefits of such use do not appear to generally outweigh the side effects. It is taken orally.
Reckitt Benckiser Group plc, trading as Reckitt, is a British multinational consumer goods company headquartered in Slough, England. It is a producer of health, hygiene and nutrition products. The company was formed in March 1999 by the merger of British company Reckitt & Colman plc and Dutch company Benckiser N.V.
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process – from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials – to approved vaccine or drug typically takes more than a decade.
Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication used to treat and prevent blood clots. Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. It is taken by mouth.
Strepsils is a brand of throat lozenges manufactured by Reckitt. Strepsils throat lozenges are used to relieve discomfort caused by mouth and throat infections.
Carolyn Ruth Bertozzi is an American chemist and Nobel laureate, known for her wide-ranging work spanning both chemistry and biology. She coined the term "bioorthogonal chemistry" for chemical reactions compatible with living systems. Her recent efforts include synthesis of chemical tools to study cell surface sugars called glycans and how they affect diseases such as cancer, inflammation, and viral infections like COVID-19. At Stanford University, she holds the Anne T. and Robert M. Bass Professorship in the School of Humanities and Sciences. Bertozzi is also an Investigator at the Howard Hughes Medical Institute (HHMI) and is the former director of the Molecular Foundry, a nanoscience research center at Lawrence Berkeley National Laboratory.
Harpic is the brand name of a toilet cleaner launched in the United Kingdom in 1932 by Reckitt and Sons. It is currently available in Africa, the Middle East, South Asia, the Asia-Pacific, Europe, and the Americas. The toilet cleaning products marketed under the brand name include liquids, tablets, wipes, brush systems, toilet rim blocks, and in-cistern blocks.
Crookes Healthcare is a healthcare manufacturer based in Nottingham, England, and a subsidiary of Reckitt. It manufactures some of the best-known health remedies and over-the-counter drugs sold by British pharmacies.
Aticaprant, also known by its developmental codes JNJ-67953964, CERC-501, and LY-2456302, is a κ-opioid receptor (KOR) antagonist which is under development for the treatment of major depressive disorder. A regulatory application for approval of the medication is expected to be submitted by 2025. Aticaprant is taken by mouth.
Indivior is a specialty pharmaceuticals business. It is listed on the London Stock Exchange and is a constituent of the FTSE 250 Index. It is also listed on the NASDAQ Global Select Market.
Kenneth John Harvey AM is an Australian public health doctor, currently Honorary Adjunct Associate Professor at the Institute for Evidence-Based Healthcare in Bond University. Described by The Age as an "anti-quackery crusader", Harvey is an advocate of evidence-based medicine and a critic of pharmaceutical marketing and unproven diet products. He is the president of Friends of Science in Medicine. In 2017, Harvey was awarded a Member of the Order of Australia (AM) for his "significant service to community health and the pharmaceutical industry”.
Nurofen is a brand name range of pain-relief medication containing ibuprofen made by the British multinational Reckitt. Introduced in 1983, the Nurofen brand was acquired following Reckitt Benckiser's acquisition of Boots in 2005. The brand is primarily marketed and sold in the United Kingdom, other parts of Europe, South Africa, Australia and New Zealand. In 2016 it was the biggest selling branded over-the-counter medication sold in Great Britain, with sales of £116.8 million.
Stewart Sanders Adams was an English pharmacist, and bioengineer who was part of a team from Boots which developed the painkiller ibuprofen in 1961. Ibuprofen is now on the World Health Organization's Model List of Essential Medicines and is one of the world's best-selling drugs.
Barry Victor Lloyd Potter MAE FMedSci is a British chemist, who is Professor of Medicinal & Biological Chemistry at the University of Oxford, Wellcome Trust Senior Investigator and a Fellow of University College, Oxford.
Paul Edward Rolan is an Australian physician, medical researcher, academic, and public health advocate. He specializes in the management of chronic pain and headache, and development of novel treatments.