This is a list containing the Billboard Hot Latin Tracks number-ones of 2008.
| Issue date | Song | Artist(s) |
|---|---|---|
| January 5 | "Me Enamora" | Juanes |
| January 12 | ||
| January 19 | "Sexy Movimiento" | Wisin & Yandel |
| January 26 | "Me Enamora" | Juanes |
| February 2 | ||
| February 9 | ||
| February 16 | ||
| February 23 | "Gotas de Agua Dulce" | |
| March 1 | "Dónde Están Corazón" | Enrique Iglesias |
| March 8 | ||
| March 15 | "Gotas de Agua Dulce" | Juanes |
| March 22 | ||
| March 29 | "Donde Están Corazón" | Enrique Iglesias |
| April 5 | "Te Quiero" | Flex |
| April 12 | ||
| April 19 | ||
| April 26 | "Si No Te Hubieras Ido" | Maná |
| May 3 | ||
| May 10 | "Te Quiero" | Flex |
| May 17 | ||
| May 24 | ||
| May 31 | ||
| June 7 | ||
| June 14 | ||
| June 21 | ||
| June 28 | ||
| July 5 | ||
| July 12 | ||
| July 19 | "Si Tú Te Vas" | Los Temerarios |
| July 26 | "Te Quiero" | Flex |
| August 2 | ||
| August 9 | ||
| August 16 | ||
| August 23 | ||
| August 30 | ||
| September 6 | ||
| September 13 | "No Me Doy Por Vencido" | Luis Fonsi |
| September 20 | ||
| September 27 | ||
| October 4 | ||
| October 11 | ||
| October 18 | ||
| October 25 | ||
| November 1 | ||
| November 8 | "Lloro Por Ti" | Enrique Iglesias |
| November 15 | ||
| November 22 | "No Me Doy por Vencido" | Luis Fonsi |
| November 29 | ||
| December 6 | ||
| December 13 | ||
| December 20 | ||
| December 26 | ||
