Serine is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group, a carboxyl group, and a side chain consisting of a hydroxymethyl group, classifying it as a polar amino acid. It can be synthesized in the human body under normal physiological circumstances, making it a nonessential amino acid. It is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC.
Phosphagens, also known as macroergic compounds, are high energy storage compounds, also known as high-energy phosphate compounds, chiefly found in muscular tissue in animals. They allow a high-energy phosphate pool to be maintained in a concentration range, which, if it all were adenosine triphosphate (ATP), would create problems due to the ATP-consuming reactions in these tissues. As muscle tissues can have sudden demands for much energy, these compounds can maintain a reserve of high-energy phosphates that can be used as needed, to provide the energy that could not be immediately supplied by glycolysis or oxidative phosphorylation. Phosphagens supply immediate but limited energy.
Earthworm Jim is a 1994 run and gun platform game developed by Shiny Entertainment, featuring an earthworm named Jim, who wears a robotic suit and battles the forces of evil. The game was released for the Sega Genesis and Super Nintendo Entertainment System, before being subsequently ported to a number of other video game consoles.
Lumbricus terrestris is a large, reddish worm species thought to be native to Western Europe, now widely distributed around the world. In some areas where it is an introduced species, some people consider it to be a significant pest for out-competing native worms.
Serine proteases are enzymes that cleave peptide bonds in proteins. Serine serves as the nucleophilic amino acid at the (enzyme's) active site. They are found ubiquitously in both eukaryotes and prokaryotes. Serine proteases fall into two broad categories based on their structure: chymotrypsin-like (trypsin-like) or subtilisin-like.
Earthworm Jim 2 is a 1995 run and gun platform video game and the sequel to Earthworm Jim, and the second and final game in the Earthworm Jim series developed by original creators Doug TenNapel, David Perry, and Shiny Entertainment. It was released in late 1995 and early 1996 depending on region and video game console, initially being released for the Sega Genesis and Super Nintendo Entertainment System, before being ported to other platforms.
The coast mole or Pacific mole is a medium-sized North American mole found in forested and open areas with moist soils along the Pacific coast from southwestern British Columbia to northwestern California.
A catalytic triad is a set of three coordinated amino acids that can be found in the active site of some enzymes. Catalytic triads are most commonly found in hydrolase and transferase enzymes. An acid-base-nucleophile triad is a common motif for generating a nucleophilic residue for covalent catalysis. The residues form a charge-relay network to polarise and activate the nucleophile, which attacks the substrate, forming a covalent intermediate which is then hydrolysed to release the product and regenerate free enzyme. The nucleophile is most commonly a serine or cysteine amino acid, but occasionally threonine or even selenocysteine. The 3D structure of the enzyme brings together the triad residues in a precise orientation, even though they may be far apart in the sequence.
Earthworm Jim is an American animated television series based on the video game series of the same name and created by series creator, Doug TenNapel. The series aired on the Kids' WB for two seasons from September 9, 1995, to December 13, 1996. It follows the adventures of the titular character who battles the forces of evil using a robotic suit.
A serine/threonine protein kinase is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid residues serine or threonine, which have similar side chains. At least 350 of the 500+ human protein kinases are serine/threonine kinases (STK).
Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP) (Vitamin B6) dependent enzyme (EC 2.1.2.1) which plays an important role in cellular one-carbon pathways by catalyzing the reversible, simultaneous conversions of L-serine to glycine and tetrahydrofolate (THF) to 5,10-Methylenetetrahydrofolate (5,10-CH2-THF). This reaction provides the largest part of the one-carbon units available to the cell.
Serine dehydratase or L-serine ammonia lyase (SDH) is in the β-family of pyridoxal phosphate-dependent (PLP) enzymes. SDH is found widely in nature, but its structural and properties vary among species. SDH is found in yeast, bacteria, and the cytoplasm of mammalian hepatocytes. SDH catalyzes is the deamination of L-serine to yield pyruvate, with the release of ammonia.
In enzymology, a serine C-palmitoyltransferase (EC 2.3.1.50) is an enzyme that catalyzes the chemical reaction:
In enzymology, a CDP-diacylglycerol—serine O-phosphatidyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a lombricine kinase is an enzyme that catalyzes the chemical reaction
In enzymology, a Fas-activated serine/threonine kinase is an enzyme that catalyzes the chemical reaction
Serine palmitoyltransferase, long chain base subunit 1, also known as SPTLC1, is a protein which in humans is encoded by the SPTLC1 gene.
Earthworm Jim is a series of platform games featuring an earthworm named Jim who wears a robotic suit and battles the forces of evil. The series is noted for its platforming and shooting gameplay, surreal humor, and edgy art style. Four games were released in the series: Earthworm Jim, Earthworm Jim 2, Earthworm Jim 3D, and Earthworm Jim: Menace 2 the Galaxy, with the first game released in 1994. The series had lain dormant for almost a decade before Gameloft remade the original game in HD for PlayStation Network and Xbox Live Arcade in 2010. Interplay announced Earthworm Jim 4 in 2008; little to no information had been surfaced until May 2019 and August 2020.
An earthworm is a soil-dwelling terrestrial invertebrate that belongs to the phylum Annelida. The term is the common name for the largest members of the class Oligochaeta. In classical systems, they were in the order of Opisthopora since the male pores opened posterior to the female pores, although the internal male segments are anterior to the female. Theoretical cladistic studies have placed them in the suborder Lumbricina of the order Haplotaxida, but this may change. Other slang names for earthworms include "dew-worm", "rainworm", "nightcrawler", and "angleworm". Larger terrestrial earthworms are also called megadriles as opposed to the microdriles in the semiaquatic families Tubificidae, Lumbricidae and Enchytraeidae. The megadriles are characterized by a distinct clitellum and a vascular system with true capillaries.
The enzyme protein serine/threonine phosphatase is a form of phosphoprotein phosphatase that acts upon phosphorylated serine/threonine residues:
