Lucy Forrest Last updated June 06, 2025 Education and career Forrest studied chemistry at the University of Surrey , UK, with a minor in computing and received her Bachelor of Science degree. [ 1] She received her Ph.D. in biochemistry from the University of Oxford [ 2] in 2000. From 2000 to 2001 Forrest was a grantee for the Fulbright Visiting Scholar Program. [ 3] Forrest participated in Eli Lilly’s research site in Windlesham , Surrey , performed postdoctoral research at Johns Hopkins University School of Medicine , and did a second postdoctoral research period at the Medical Research Council 's Dunn Human Nutrition Unit in Cambridge, UK . [ 4] She moved to New York City , NY , USA in 2003 to work at Columbia University Medical School. [ 4] In 2007, Forrest was designated the Max Planck Research Group Leader at the Max Planck Institute for Biophysics in Frankfurt, Germany . [ 2] Forrest has worked at the National Institutes of Health in Bethesda, MD , USA since 2013. [ 1] She received tenure in 2017 and was promoted to Senior Investigator. [ 5]
Research Forrest's early research centered on simulating and modeling membrane proteins in lipid bilayers . [ 6] [ 7] She also examines secondary transport mechanisms, [ 8] and has developed a database that allows for comparison of structural differences in membrane proteins. [ 9] [ 10]
Selected publications Forrest, Lucy R.; Zhang, Yuan-Wei; Jacobs, Miriam T.; Gesmonde, Joan; Xie, Li; Honig, Barry H.; Rudnick, Gary (2008-07-29). "Mechanism for alternating access in neurotransmitter transporters" . Proceedings of the National Academy of Sciences . 105 (30): 10338– 10343. Bibcode :2008PNAS..10510338F . doi : 10.1073/pnas.0804659105 . ISSN 0027-8424 . PMC 2480614 . PMID 18647834 . Forrest, Lucy R.; Rudnick, Gary (2009). "The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters" . Physiology . 24 (6): 377– 386. doi :10.1152/physiol.00030.2009 . ISSN 1548-9213 . PMC 3012352 . PMID 19996368 . Forrest, Lucy R.; Krämer, Reinhard; Ziegler, Christine (2011-02-01). "The structural basis of secondary active transport mechanisms" . Biochimica et Biophysica Acta (BBA) - Bioenergetics . 1807 (2): 167– 188. doi :10.1016/j.bbabio.2010.10.014 . ISSN 0005-2728 . PMID 21029721 . Liao, Ya-Cheng; Fernandopulle, Michael S.; Wang, Guozhen; Choi, Heejun; Hao, Ling; Drerup, Catherine M.; Patel, Rajan; Qamar, Seema; Nixon-Abell, Jonathon; Shen, Yi; Meadows, William; Vendruscolo, Michele; Knowles, Tuomas P. J.; Nelson, Matthew; Czekalska, Magdalena A. (2019-09-19). "RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether" . Cell . 179 (1): 147–164.e20. doi :10.1016/j.cell.2019.08.050 . ISSN 0092-8674 . PMC 6890474 . PMID 31539493 . Honors and awards In 2012, she was a recipient of the Margaret Oakley Dayhoff Award for her research on “conformational changes of membrane proteins related to their function, and her impact on the field of computational structural biology”. [ 11]
References 1 2 "Colleagues: Recently Tenured" . The NIH Catalyst . Retrieved 2025-05-08 . 1 2 "Lucy R. Forrest, D.Phil. | NINDS Division of Intramural Research" . research.ninds.nih.gov . Retrieved 2024-05-16 . ↑ "University of Oxford | Fulbright Scholar Program" . fulbrightscholars.org . Retrieved 2024-05-16 . 1 2 Gordon, Sharona E. (2014). "Introducing the new members of the JGP Editorial Advisory Board" . Journal of General Physiology . 143 (3): 309– 312. doi :10.1085/jgp.201411177 . Retrieved 2024-05-16 . ↑ "Computational Structural Biology Section | NINDS Division of Intramural Research" . National Institute of Neurological Disorders and Stroke, NIH . Retrieved 2024-05-16 . ↑ Forrest, Lucy R; Sansom, Mark SP (2000-04-01). "Membrane simulations: bigger and better?" . Current Opinion in Structural Biology . 10 (2): 174– 181. doi :10.1016/S0959-440X(00)00066-X . ISSN 0959-440X . PMID 10753807 . ↑ Forrest, Lucy R.; Tang, Christopher L.; Honig, Barry (2006-07-15). "On the Accuracy of Homology Modeling and Sequence Alignment Methods Applied to Membrane Proteins" . Biophysical Journal . 91 (2): 508– 517. Bibcode :2006BpJ....91..508F . doi :10.1529/biophysj.106.082313 . ISSN 0006-3495 . PMC 1483079 . PMID 16648166 . ↑ Forrest, Lucy R.; Krämer, Reinhard; Ziegler, Christine (2011-02-01). "The structural basis of secondary active transport mechanisms" . Biochimica et Biophysica Acta (BBA) - Bioenergetics . 1807 (2): 167– 188. doi :10.1016/j.bbabio.2010.10.014 . ISSN 0005-2728 . PMID 21029721 . ↑ Miller, Chris (2018). "A mighty stream of membrane proteins" . Nature Structural & Molecular Biology . 25 (9): 751– 753. doi :10.1038/s41594-018-0121-x . ISSN 1545-9993 . PMID 30150646 . ↑ Sarti, Edoardo; Aleksandrova, Antoniya A; Ganta, Srujan K; Yavatkar, Amarendra S; Forrest, Lucy R (2019-01-08). "EncoMPASS: an online database for analyzing structure and symmetry in membrane proteins" . Nucleic Acids Research . 47 (D1): D315 – D321 . doi :10.1093/nar/gky952 . ISSN 0305-1048 . PMC 6323976 . PMID 30357403 . ↑ "Biophysical Society names 5 2012 award recipients" . sciencex.com . September 6, 2011. Retrieved 2024-05-30 . This page is based on this
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