MBTD1

MBTD1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3FEO, 4C5I
Identifiers
Aliases	MBTD1 , SA49P01, mbt domain containing 1
External IDs	MGI: 2143977; HomoloGene: 41185; GeneCards: MBTD1; OMA:MBTD1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q21.33 Start 51,177,425 bp [1] End 51,260,163 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 D Start 93,776,678 bp [2] End 93,837,811 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of thigh tibia germinal epithelium buccal mucosa cell parietal pleura visceral pleura ganglionic eminence amniotic fluid skin of hip palpebral conjunctiva Top expressed in Rostral migratory stream zygote secondary oocyte medial ganglionic eminence primary oocyte maxillary prominence medullary collecting duct ventricular zone mandibular prominence vas deferens More reference expression data BioGPS n/a
Gene ontology Molecular function zinc ion binding metal ion binding methylated histone binding Cellular component nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated embryonic skeletal system development chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54799 103537 Ensembl ENSG00000011258 ENSMUSG00000059474 UniProt Q05BQ5 Q6P5G3 RefSeq (mRNA) NM_017643 NM_134012 NM_001346525 NM_001363336 RefSeq (protein) NP_060113 NP_001333454 NP_598773 NP_001350265 Location (UCSC) Chr 17: 51.18 – 51.26 Mb Chr 11: 93.78 – 93.84 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Malignant Brain Tumor domain containing 1 is a protein that in humans is encoded by the MBTD1 gene. ^[5] The gene is also known as SA49P01. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000011258 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059474 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Malignant Brain Tumor domain containing 1" . Retrieved 2011-12-05.

Further reading

• Eryilmaz J, Pan P, Amaya MF, Allali-Hassani A, Dong A, Adams-Cioaba MA, et al. (October 2009). Gay N (ed.). "Structural studies of a four-MBT repeat protein MBTD1". PLOS ONE. 4 (10) e7274. Bibcode:2009PLoSO...4.7274E. doi: 10.1371/journal.pone.0007274 . PMC   2747274 . PMID   19841675.
• Hayakawa T, Ohtani Y, Hayakawa N, Shinmyozu K, Saito M, Ishikawa F, Nakayama J (June 2007). "RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation". Genes to Cells. 12 (6): 811–826. doi: 10.1111/j.1365-2443.2007.01089.x . PMID   17573780.