MEI1

MEI1
Identifiers
Aliases	MEI1 , SPATA38, meiotic double-stranded break formation protein 1, HYDM3
External IDs	OMIM: 608797 MGI: 3028590 HomoloGene: 46535 GeneCards: MEI1
Gene location (Human)
Chr.	Chromosome 22 (human)
End	41,799,456 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	82,011,015 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; spleen; ; appendix; ; blood; ; lymph node; ; rectum; ; monocyte; ; minor salivary gland; ; thymus; ; pancreatic ductal cell;
	Top expressed in
	otolith organ; ; utricle; ; morula; ; spermatid; ; superior frontal gyrus; ; seminiferous tubule; ; spermatocyte; ; submandibular gland; ; free upper limb; ; triceps brachii muscle;
	More reference expression data
	n/a
Orthologs
	150365
	74369
	ENSG00000167077
	ENSMUSG00000068117
	Q5TIA1 ; Q4G0I1
	Q9D4I2
	NM_152513
	NM_028897 ; NM_001310435
	NP_689726 ; NP_689726.3
	NP_001297364 ; NP_083173
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 05, 2023

Meiotic double-stranded break formation protein 1 is a protein that in humans is encoded by the MEI1 gene. ^[5]

Related Research Articles

Spo11 is a protein that in humans is encoded by the SPO11 gene. Spo11, in a complex with mTopVIB, creates double strand breaks to initiate meiotic recombination. Its active site contains a tyrosine which ligates and dissociates with DNA to promote break formation. One Spo11 protein is involved per strand of DNA, thus two Spo11 proteins are involved in each double stranded break event.

Meiotic recombination protein DMC1/LIM15 homolog is a protein that in humans is encoded by the DMC1 gene.

Olfactory receptor 8H1 is a protein that in humans is encoded by the OR8H1 gene.

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DNA repair and recombination protein RAD54B is a protein that in humans is encoded by the RAD54B gene.

Zinc finger protein 346 is a protein that in humans is encoded by the ZNF346 gene.

Kelch domain-containing protein 3 is a protein that in humans is encoded by the KLHDC3 gene.

Single-stranded DNA-binding protein 3 is a protein that in humans is encoded by the SSBP3 gene.

PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene.

HORMA domain-containing protein 1 (HORMAD1) also known as cancer/testis antigen 46 (CT46) is a protein that in humans is encoded by the HORMAD1 gene.

DNA replication licensing factor MCM8 is a protein that in humans is encoded by the MCM8 gene.

Gap junction delta-4 protein (GJD4), also known as connexin-40.1 (Cx40.1), is a protein that in humans is encoded by the GJD4 gene.

Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.

BarH-like homeobox 2 is a protein in humans that is encoded by the BARHL2 gene.

BRCA1-associated ATM activator 1 is a protein in humans that is encoded by the BRAT1 gene.

Testis expressed 15 is a protein that in humans is encoded by the TEX15 gene.

Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein.

Cell cycle regulator of non-homologous end joining is a protein that in humans is encoded by the CYREN gene.

Single-stranded DNA-binding protein 4 is a protein that in humans is encoded by the SSBP4 gene.

E3 ubiquitin-protein ligase RNF114 is a protein that in humans is encoded by the RNF114 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000167077 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000068117 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Meiotic double-stranded break formation protein 1" . Retrieved 2017-03-25.

MEI1

Related Research Articles

References

Further reading