MGC3207

MRI1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4LDQ, 4LDR
Identifiers
Aliases	MRI1 , MRDI, MTNA, Ypr118w, MGC3207, methylthioribose-1-phosphate isomerase 1, M1Pi
External IDs	OMIM: 615105 MGI: 1915123 HomoloGene: 7160 GeneCards: MRI1
Gene location (Human)
Chr.	Chromosome 19 (human)
End	13,774,282 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	84,983,955 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; canal of the cervix; ; sural nerve; ; skin of abdomen; ; left lobe of thyroid gland; ; minor salivary gland; ; right lobe of thyroid gland; ; left uterine tube; ; left coronary artery; ; body of stomach;
	Top expressed in
	left lobe of liver; ; neural tube; ; proximal tubule; ; adrenal gland; ; lip; ; knee joint; ; seminal vesicula; ; skeletal muscle tissue; ; yolk sac; ; quadriceps femoris muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	isomerase activity ; identical protein binding ; S-methyl-5-thioribose-1-phosphate isomerase activity ;
Cellular component	cell projection ; nucleus ; fibrillar center ; nucleoplasm ; cytosol ; cytoplasm ;
Biological process	cellular biosynthetic process ; methionine biosynthetic process ; L-methionine salvage from methylthioadenosine ; cell metabolism ; cellular amino acid biosynthetic process ; L-methionine salvage from S-adenosylmethionine ;
	Sources:Amigo / QuickGO
Orthologs
	84245
	67873
	ENSG00000037757
	ENSMUSG00000004996
	Q9BV20
	Q9CQT1
	NM_001031727 ; NM_032285 ; NM_001329572
	NM_026423
	NP_001026897 ; NP_001316501 ; NP_115661
	NP_080699
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 30, 2022

Methylthioribose-1-phosphate isomerase is an enzyme that in humans is encoded by the MRI1 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000037757 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004996 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Bumann M, Djafarzadeh S, Oberholzer AE, Bigler P, Altmann M, Trachsel H, Baumann U (Aug 2004). "Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits". J Biol Chem. 279 (35): 37087–94. doi: 10.1074/jbc.M404458200 . PMID 15215245.
↑ "Entrez Gene: MGC3207 hypothetical protein MGC3207".

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732 . PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148 . PMID 15231748.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000037757 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004996 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15215245-5] Bumann M, Djafarzadeh S, Oberholzer AE, Bigler P, Altmann M, Trachsel H, Baumann U (Aug 2004). "Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits". J Biol Chem. 279 (35): 37087–94. doi: 10.1074/jbc.M404458200 . PMID 15215245.

[entrez-6] "Entrez Gene: MGC3207 hypothetical protein MGC3207".

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MGC3207

Related Research Articles

References

Further reading