MLLT6

MLLT6
Identifiers
Aliases	MLLT6 , AF17, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6, PHD finger containing
External IDs	OMIM: 600328; MGI: 1935145; HomoloGene: 31347; GeneCards: MLLT6; OMA:MLLT6 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q12 Start 38,705,273 bp [1] End 38,729,795 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11 D|11 61.05 cM Start 97,554,240 bp [2] End 97,576,289 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube Pituitary Gland left ovary right lobe of thyroid gland right ovary granulocyte sural nerve anterior pituitary left lobe of thyroid gland appendix Top expressed in neural layer of retina ciliary body mesenteric lymph nodes retinal pigment epithelium vestibular membrane of cochlear duct dorsal striatum Region I of hippocampus proper olfactory tubercle habenula superior colliculus More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding protein binding nucleosome binding histone binding Cellular component nucleus Biological process regulation of transcription, DNA-templated renal system process excretion positive regulation of sodium ion transport negative regulation of urine volume renal sodium excretion renal potassium excretion positive regulation of transcription by RNA polymerase II negative regulation of histone H3-K79 methylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4302 246198 Ensembl ENSG00000275023 ENSG00000275851 ENSMUSG00000038437 UniProt P55198 Q6P2C6 n/a RefSeq (mRNA) NM_005937 NM_139311 RefSeq (protein) NP_005928 n/a Location (UCSC) Chr 17: 38.71 – 38.73 Mb Chr 11: 97.55 – 97.58 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

MLLT6, PHD finger containing is a protein that in humans is encoded by the MLLT6 gene. ^[5]

See also

• PHD finger

References

1. ENSG00000275851 GRCh38: Ensembl release 89: ENSG00000275023, ENSG00000275851 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038437 – Ensembl, May 2017
3. '"`UNIQ--templatestyles-00000006-QINU`"' "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. '"`UNIQ--templatestyles-00000008-QINU`"' "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: MLLT6, PHD finger containing" . Retrieved 2018-10-19.

Further reading

• Pan JL, Xue YQ, Jiang HY, He J, Wang W, Wu YF (August 2005). "[Application of reverse transcription-multiplex nested PCR to detect MLL rearrangement in AML-M4/M5]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi (in Chinese). 22 (4): 444–6. PMID   16086288.