MRCL3

MYL12A
Identifiers
Aliases	MYL12A , HEL-S-24, MLCB, MRCL3, MRLC3, MYL2B, MLC-2B, myosin light chain 12A
External IDs	MGI: 107494; HomoloGene: 23407; GeneCards: MYL12A; OMA:MYL12A - orthologs
Gene location (Human) Chr. Chromosome 18 (human) [1] Band 18p11.31 Start 3,247,481 bp [1] End 3,256,236 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 E1.3 Start 71,280,128 bp [2] End 71,297,885 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart muscle of thigh right auricle of heart monocyte right lung granulocyte upper lobe of left lung right coronary artery ascending aorta left coronary artery Top expressed in granulocyte primary visual cortex superior frontal gyrus yolk sac lip right kidney dentate gyrus of hippocampal formation granule cell ventricular zone embryo blastocyst More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding protein binding metal ion binding myosin heavy chain binding Cellular component cytosol extracellular exosome myosin complex myosin II complex apical part of cell Z discdkac brush border stress fiber cell cortex region Biological process ephrin receptor signaling pathway muscle contraction platelet aggregation regulation of cell shape Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10627 67938 Ensembl ENSG00000101608 ENSMUSG00000034868 UniProt P19105 O14950 Q3THE2 RefSeq (mRNA) NM_001303047 NM_001303048 NM_001303049 NM_006471 NM_023402 RefSeq (protein) NP_001289976 NP_001289977 NP_001289978 NP_006462 NP_001138416 NP_001138417 NP_291024 NP_001289976 NP_001289977 NP_001289978 NP_006462 NP_075891 Location (UCSC) Chr 18: 3.25 – 3.26 Mb Chr 17: 71.28 – 71.3 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Myosin regulatory light chain 12A is a protein that in humans is encoded by the MYL12A gene. ^{[5] [6]}

See also

• Myosin light chain

References

1. GRCh38: Ensembl release 89: ENSG00000101608 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000034868 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Grant JW, Zhong RQ, McEwen PM, Church SL (Nov 1990). "Human nonsarcomeric 20,000 Da myosin regulatory light chain cDNA". Nucleic Acids Res. 18 (19): 5892. doi:10.1093/nar/18.19.5892. PMC   332341 . PMID   2216787.
6. "Entrez Gene: MRCL3 myosin regulatory light chain MRCL3".

Further reading

• Kobayashi K, Xin Y, Ymer SI, et al. (2007). "Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells". Brain Res. 1170: 129–39. doi:10.1016/j.brainres.2007.07.042. PMID   17719568. S2CID   31320196.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID   14743216. S2CID   11683986.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Iwasaki T, Murata-Hori M, Ishitobi S, Hosoya H (2002). "Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells". Cell Struct. Funct. 26 (6): 677–83. doi: 10.1247/csf.26.677 . PMID   11942626.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.