MRM1 (gene)

MRM1
Identifiers
Aliases	MRM1 , mitochondrial rRNA methyltransferase 1
External IDs	OMIM: 618099; MGI: 2443470; HomoloGene: 40307; GeneCards: MRM1; OMA:MRM1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q12 Start 36,601,583 bp [1] End 36,608,964 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 C Start 84,703,887 bp [2] End 84,710,341 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad mucosa of transverse colon apex of heart gastrocnemius muscle granulocyte left ventricle right adrenal gland left adrenal gland right lobe of liver right adrenal cortex Top expressed in interventricular septum extraocular muscle yolk sac right ventricle myocardium of ventricle cumulus cell aortic valve fetal liver hematopoietic progenitor cell granulocyte soleus muscle More reference expression data BioGPS n/a
Gene ontology Molecular function methyltransferase activity RNA methyltransferase activity transferase activity protein binding rRNA (guanosine-2'-O-)-methyltransferase activity RNA binding Cellular component mitochondrion mitochondrial matrix Biological process rRNA processing methylation RNA processing enzyme-directed rRNA 2'-O-methylation rRNA 2'-O-methylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79922 217038 Ensembl ENSG00000274853 ENSG00000278619 ENSMUSG00000018405 UniProt Q6IN84 Q99J25 RefSeq (mRNA) NM_024864 NM_145433 RefSeq (protein) NP_079140 NP_663408 Location (UCSC) Chr 17: 36.6 – 36.61 Mb Chr 11: 84.7 – 84.71 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Mitochondrial rRNA methyltransferase 1 is a protein that in humans is encoded by the MRM1 gene. ^[5]

References

1. ENSG00000278619 GRCh38: Ensembl release 89: ENSG00000274853, ENSG00000278619 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000018405 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Mitochondrial rRNA methyltransferase 1" . Retrieved 2020-04-12.

Further reading

• Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (September 2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLOS ONE. 5 (9): e12862. Bibcode:2010PLoSO...512862H. doi: 10.1371/journal.pone.0012862 . PMC   2943476 . PMID   20877624.