MXRA7

MXRA7
Identifiers
Aliases	MXRA7 , matrix remodeling associated 7
External IDs	HomoloGene: 134006; GeneCards: MXRA7; OMA:MXRA7 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q25.1 Start 76,672,551 bp [1] End 76,711,004 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in saphenous vein decidua retinal pigment epithelium urethra vena cava beta cell seminal vesicula Epithelium of choroid plexus skin of hip synovial joint n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 439921 n/a Ensembl ENSG00000182534 n/a UniProt P84157 n/a RefSeq (mRNA) NM_001008528 NM_001008529 NM_198530 NM_001363769 NM_001387276 NM_001387277 NM_001387278 n/a RefSeq (protein) NP_001008528 NP_001008529 NP_940932 NP_001350698 n/a Location (UCSC) Chr 17: 76.67 – 76.71 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Matrix remodeling associated 7 is a protein that in humans is encoded by the MXRA7 gene found on chromosome 17. ^[3] Loss-of-function studies performed in MXRA7-deficient mice, ^{[4] [5] [6]} in line with other types of data ^{[7] [8] [9] [10]} suggested that this gene was involved in multiple physiological or pathological processes. ^[11]

References

1. GRCh38: Ensembl release 89: ENSG00000182534 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: Matrix remodeling associated 7" . Retrieved 2019-08-06.
4. Zhou Z, Shen Y, Yin J, Xi F, Xu R, Lin D, et al. (August 2019). "Matrix remodeling associated 7 promotes differentiation of bone marrow mesenchymal stem cells toward osteoblasts". Journal of Cellular Physiology. 234 (10): 18053–18064. doi:10.1002/jcp.28438. PMID   30843215. S2CID   73475103.
5. Ning J, Shen Y, Wang T, Wang M, Liu W, Sun Y, et al. (September 2018). "Altered expression of matrix remodelling associated 7 (MXRA7) in psoriatic epidermis: Evidence for a protective role in the psoriasis imiquimod mouse model". Experimental Dermatology. 27 (9): 1038–1042. doi:10.1111/exd.13687. PMID   29781547. S2CID   29152069.
6. Lin D, Sun Z, Jin Z, Lei L, Liu Y, Hu B, et al. (2018). "Matrix Remodeling Associated 7 Deficiency Alleviates Carbon Tetrachloride-Induced Acute Liver Injury in Mice". Frontiers in Immunology. 9: 773. doi: 10.3389/fimmu.2018.00773 . PMC   5915751 . PMID   29720975.
7. Jia C, Zhang F, Zhu Y, Qi X, Wang Y (October 2017). "Public data mining plus domestic experimental study defined involvement of the old-yet-uncharacterized gene matrix-remodeling associated 7 (MXRA7) in physiopathology of the eye". Gene. 632: 43–49. doi: 10.1016/j.gene.2017.08.018 . PMID   28847716.
8. Long NP, Park S, Anh NH, Min JE, Yoon SJ, Kim HM, et al. (January 2019). "Efficacy of Integrating a Novel 16-Gene Biomarker Panel and Intelligence Classifiers for Differential Diagnosis of Rheumatoid Arthritis and Osteoarthritis". Journal of Clinical Medicine. 8 (1): 50. doi: 10.3390/jcm8010050 . PMC   6352223 . PMID   30621359.
9. Veiga-Castelli LC, Silva JC, Meola J, Ferriani RA, Yoshimoto M, Santos SA, et al. (August 2010). "Genomic alterations detected by comparative genomic hybridization in ovarian endometriomas". Brazilian Journal of Medical and Biological Research. 43 (8): 799–805. doi: 10.1590/s0100-879x2010007500072 . PMID   20725696.
10. Wang M, Shen Y, Li Y, Wang Y (2019). "Potential Partners of Matrix-Remodeling Associated 7 (MXRA7) in Murine Liver". Chinese Journal of Biochemistry and Molecular Biology. 35 (1): 51–66.
11. Wang Y (2020). "Matrix Remodeling Associated 7 (MXRA7): a Long-lost Member of the Non-kin MXRA Family". Chinese Journal of Biochemistry and Molecular Biology. 36 (7): 725–733. doi:10.13865/j.cnki.cjbmb.2020.06.1130.