Trastuzumab,sold under the brand name Herceptin among others,is a monoclonal antibody used to treat breast cancer and stomach cancer. It is specifically used for cancer that is HER2 receptor positive. It may be used by itself or together with other chemotherapy medication. Trastuzumab is given by slow injection into a vein and injection just under the skin.
Bevacizumab,sold under the brand name Avastin among others,is a medication used to treat a number of types of cancers and a specific eye disease. For cancer,it is given by slow injection into a vein (intravenous) and used for colon cancer,lung cancer,glioblastoma,and renal-cell carcinoma. In many of these diseases it is used as a first-line therapy. For age-related macular degeneration it is given by injection into the eye (intravitreal).
The Yale School of Public Health (YSPH) was founded in 1915 by Charles-Edward Amory Winslow and is one of the oldest public health masters programs in the United States. It is consistently rated among the best schools of public health in the country,receiving recent rankings of 3rd for its doctoral program in epidemiology. YSPH is both a department within the school of medicine as well as an independent,CEPH-certified school of public health.
David B. Agus is an American physician,cancer researcher and author who serves as a professor of medicine and engineering at the University of Southern California Keck School of Medicine and Viterbi School of Engineering and the Founding Director and CEO of the Lawrence J. Ellison Institute for Transformative Medicine. He is also the cofounder of several personalized medicine companies and a contributor to CBS News on health topics. He is also the author of four books.
Alpelisib,sold under the brand name Piqray among others,is a medication used to treat certain types of breast cancer. It is used together with fulvestrant. It is taken by mouth. It is marketed by Novartis.
Jill Wruble is a radiologist and fellow at Johns Hopkins Medicine who is best known as a speaker on overdiagnosis due to incidental imaging finding in United States medicine.
Tucatinib,sold under the brand name Tukysa,is an anticancer medication used for the treatment of HER2-positive breast cancer. It is a small molecule inhibitor of HER2. It was developed by Array BioPharma and licensed to Cascadian Therapeutics.
Trastuzumab deruxtecan,sold under the brand name Enhertu,is an antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab (Herceptin) covalently linked to the topoisomerase I inhibitor deruxtecan. It is licensed for the treatment of breast cancer or gastric or gastroesophageal adenocarcinoma. Trastuzumab binds to and blocks signaling through epidermal growth factor receptor 2 (HER2/neu) on cancers that rely on it for growth. Additionally,once bound to HER2 receptors,the antibody is internalized by the cell,carrying the bound deruxtecan along with it,where it interferes with the cell's ability to make DNA structural changes and replicate its DNA during cell division,leading to DNA damage when the cell attempts to replicate itself,destroying the cell.
Tatiana Michelle Prowell is an American medical oncologist specializing in breast cancer. She is an Associate Professor of Oncology at Johns Hopkins School of Medicine and Breast Cancer Scientific Liaison at the U.S. Food &Drug Administration.
Maryam Beheshti Lustberg is an American breast oncologist. She is the Director of The Breast Center at Smilow Cancer Hospital and Chief of Breast Medical Oncology at Yale Cancer Center. Lustberg previously served as the Medical Director of Supportive Care at Ohio State's Comprehensive Cancer Center and President-Elect of the Multinational Association of Supportive Care in Cancer. She is also an associate editor for the peer-reviewed medical journal covering oncology nursing with respect to cancer survivors called Journal of Cancer Survivorship.
Marcella Nunez-Smith is an American physician-scientist. She is C.N.H Long Professor of medicine and epidemiology at the Yale School of Medicine,where she serves as the inaugural Associate Dean for Health Equity Research and founding director of the Equity Research and Innovation Center. She also holds joint appointments at the Yale School of Public Health and the Yale School of Management. After co-chairing the Biden-Harris transition’s COVID-19 Advisory Board from November 2020 to January 2021,she was selected by President Joe Biden to serve as Senior Advisor to the White House COVID-19 Response Team and Chair of the Presidential COVID-19 Equity Task Force.
Katrina Alison Armstrong,MD is an American internist. She is the chief executive officer of the Columbia University Irving Medical Center and Dean of the Faculties of Health Sciences and the Columbia University Vagelos College of Physicians and Surgeons. Armstrong is the first woman to lead Columbia's medical school and medical center. Previously,she was the first woman to hold the position of Physician-in-Chief at Massachusetts General Hospital and was elected to the National Academy of Medicine in 2013 and the American Academy of Arts and Sciences in 2020.
Cheryl Ann Koopman was an American social psychologist,behavioral scientist,and international relations scholar. As a professor of psychiatry and behavioral sciences at Stanford University and the Stanford University School of Medicine,Koopman was an expert on the social and political context of diseases and diagnosis,quality of life interventions among people living with cancer,and the psychology of problems in international relations like nuclear war prevention. She was the President of the International Society of Political Psychology.
Gina Danielle Schellenbaum Lovasi is the Urban Health Collaborative Co-Director and Dornsife Associate Professor of Urban Health at Drexel University. She has authored more than 100 peer-reviewed articles and co-edited the book Urban Public Health:A Research Toolkit for Practice and Impact.
Lori Jo Pierce is an American radiation oncologist and 57th President of the American Society of Clinical Oncology. She is a Full Professor and Vice Provost for Academic and Faculty Affairs at the University of Michigan. Her research focuses on the use of radiotherapy in the multi-modality treatment of breast cancer,with emphasis on intensity modulated radiotherapy in node positive breast cancer,the use of radiosensitizing agents,and the outcomes of women treated with radiation for breast cancer who are carriers of a BRCA1/2 breast cancer susceptibility gene.
Ana Abraído-Lanza is an American behavioral psychologist who is a professor at the New York University. Her research considers the cultural and structural factors that impact mental and physical health amongst Latino communities. She serves as Vice Dean of the School of Public Health.
Cheryl Healton is an American public health researcher who is Professor of Public Health Policy and Dean of School of Global Public Health at New York University. Her research considers public health policy surrounding tobacco control.
Robin Meryl Masheb is an American psychologist. She is a Full Professor of Psychiatry at Yale University and Director of the Veterans Initiative for Eating and Weight. The program is dedicated to addressing eating and weight problems in veterans through research,training and advocacy.
Nancy Lin is an American oncologist who works at the Dana-Farber Cancer Institute and is an Associate Professor of Medicine at Harvard Medical School. Her research considers new diagnostic strategies and treatment pathways for HER2 positive breast cancer.
Fatima Cody Stanford is an American obesity medicine physician,internist,and pediatrician and an associate professor of medicine and pediatrics at Harvard Medical School. She is one of the most highly cited scientists in the field of obesity. She is recognized for shifting the global perception of obesity as a chronic disease.
