Megan Clarke | |
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 Clarke in 2018 | |
| Alma mater | Johns Hopkins Bloomberg School of Public Health |
| Scientific career | |
| Fields | Cancer epidemiology, DNA methylation |
| Institutions | National Institutes of Health |
| Doctoral advisor | Corinne Joshu |
Megan A. Clarke is an American cancer epidemiologist who researches anogenital and endometrial cancers. She is a Stadtman investigator in the clinical genetics branch at the National Cancer Institute.
Clarke was a postbaccalaureate fellow in the clinical genetics branch (CGB) at the National Cancer Institute (NCI). [1] She completed a M.H.S. in biochemistry and molecular biology in 2010 and a Ph.D. in epidemiology in 2016, both from the Johns Hopkins Bloomberg School of Public Health. [1] Her dissertation was titled, Early-life exposures and adult cancer risk: a life course approach to cancer prevention. [2] Corinne Joshu was her doctoral advisor. [2] Clarke was a postdoctoral cancer prevention fellow at the CGB. [1]
Clark was promoted to research fellow in 2019 and was appointed as an Earl Stadtman Tenure-Track Investigator in 2020. [1] She conducts research combining molecular, clinical, and population-based approaches to address etiology, prevention, and early detection of anogenital and endometrial cancers, yielding results that inform natural history and clinical management and address cancer disparities. Clarke studies cervical cancer disparities including race, ethnicity, and other factors such as obesity. [1] She identified host gene and HPV DNA methylation as potential biomarkers for cervical carcinogenesis. [1] Clarke collaborates with the NCI cancer genome research laboratory to develop a low-cost, next-generation sequencing methylation assay. [1] She leads efforts to validate this assay in natural history studies and has designed a study (Selfie) for large-scale evaluation of methylation testing in self-collected samples. [1]
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship.
The Johns Hopkins University School of Nursing (JHUSON) is the nursing school of Johns Hopkins University in Baltimore, Maryland. Established in 1889, it is one of the nation's oldest schools for nursing education. It is continuously rated as the top nursing program in the US per U.S. News & World Report.
Gynecologic cancer disparities in the United States refer to differences in incidence, prevalence, and mortality from gynecologic cancers between population groups. The five main types of gynecologic cancer include cervical cancer, ovarian cancer, endometrial cancer, vaginal cancer, and vulvar cancer. For patients with these and other gynecologic malignancies within the United States, disparities across the care continuum by socioeconomic status and racial/ethnic background have been previously identified and studied. The causes behind these disparities are multifaceted and a complex interplay of systemic differences in health as well as individual patient factors such as cultural, educational, and economic barriers.
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Ruth A. Kleinerman is an American epidemiologist specialized in retinoblastoma. Kleinerman worked at the National Cancer Institute (NCI) from 1979 to 2019 where she served as a staff scientist and deputy chief of the Radiation Epidemiology Branch.
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Mia M. Gaudet is an American molecular epidemiologist pectized in cancer prevention research and managing cohort studies. She is a senior scientist in the division of cancer epidemiology and genetics at the National Cancer Institute.
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Stephanie Joan Weinstein is an American nutritionist and cancer epidemiologist who is a staff scientist in the metabolic epidemiology branch at the National Cancer Institute. She researches diet and cancer associations with a with a focus on vitamin D, vitamin E, and one-carbon metabolism. Weinstein was formerly an environmental toxicologist at a consulting firm.
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This article incorporates text from this source, which is in the public domain . This article incorporates public domain material from websites or documents of the National Institutes of Health.| General | |
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