Membrane bound o-acyltransferase domain containing 2

MBOAT2
Identifiers
Aliases	MBOAT2 , LPCAT4, OACT2, LPAAT, LPEAT, LPLAT 2, membrane bound O-acyltransferase domain containing 2, LPCAT
External IDs	OMIM: 611949 MGI: 1914466 HomoloGene: 6971 GeneCards: MBOAT2
EC number	2.3.1.51
Gene location (Human)
Chr.	Chromosome 2 (human)
End	9,003,709 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	25,014,396 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; gums; ; cavity of mouth; ; ganglionic eminence; ; tibial nerve; ; cancellous bone; ; skin of abdomen; ; palpebral conjunctiva; ; Region I of hippocampus proper; ; bone marrow;
	Top expressed in
	belly cord; ; otic placode; ; sciatic nerve; ; condyle; ; Epithelium of stomach; ; saccule; ; ciliary body; ; iris; ; cervix; ; islet of Langerhans;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity ; acyltransferase activity ; 1-acylglycerol-3-phosphate O-acyltransferase activity ; 2-acylglycerol-3-phosphate O-acyltransferase activity ;
Cellular component	integral component of membrane ; endoplasmic reticulum membrane ; membrane ;
Biological process	phosphatidylethanolamine acyl-chain remodeling ; phosphatidylcholine acyl-chain remodeling ; lipid metabolism ; phospholipid biosynthetic process ; phospholipid metabolic process ;
	Sources:Amigo / QuickGO
Orthologs
	129642
	67216
	ENSG00000143797
	ENSMUSG00000020646
	Q6ZWT7
	Q8R3I2
	NM_138799 ; NM_001321265 ; NM_001321266 ; NM_001321267
	NM_001083341 ; NM_026037
	NP_001308194 ; NP_001308195 ; NP_001308196 ; NP_620154
	NP_001076810 ; NP_080313
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Membrane bound O-acyltransferase domain containing 2 is a protein that in humans is encoded by the MBOAT2 gene. ^[5]

Related Research Articles

Membrane-bound transcription factor site-1 protease, or site-1 protease (S1P) for short, also known as subtilisin/kexin-isozyme 1 (SKI-1), is an enzyme that in humans is encoded by the MBTPS1 gene. S1P cleaves the endoplasmic reticulum loop of sterol regulatory element-binding protein (SREBP) transcription factors.

Natriuretic peptide receptor A/guanylate cyclase A , also known as NPR1, is an atrial natriuretic peptide receptor. In humans it is encoded by the NPR1 gene.

Myotubularin-related protein 3 is a protein that in humans is encoded by the MTMR3 gene.

Lysophospholipid acyltransferase 5 is an enzyme that in humans is encoded by the LPCAT3 gene. It is homologous to other membrane-bound O-acyltransferases.

Patatin-like phospholipase domain-containing protein 3 (PNPLA3) also known as adiponutrin (ADPN), acylglycerol O-acyltransferase or calcium-independent phospholipase A2-epsilon (iPLA2-epsilon) is an enzyme that in humans is encoded by the PNPLA3 gene.

PORCN is a human gene. The protein is homologous to other membrane-bound O-acyltransferases.

Dipeptidase 2 (DPEP2) is a protein which in humans is encoded by the DPEP2 gene.

Zinc finger and BTB domain containing 11 is a protein that in humans is encoded by the ZBTB11 gene.

Solute carrier family 25, member 16 is a protein in humans that is encoded by the SLC25A16 gene.

Lysophospholipid acyltransferase 7 also known as membrane-bound O-acyltransferase domain-containing protein 7 (MBOAT7) is an enzyme that in humans is encoded by the MBOAT7 gene. It is homologous to other membrane-bound O-acyltransferases.

Motile sperm domain containing 2 is a protein that in humans is encoded by the MOSPD2 gene. It is an endoplasmic reticulum–resident protein involved in membrane contact site formation. Its domain homologous to Major Sperm Protein is very similar to VAPA/VAPB, so it has been described as the third human member of the VAP protein family.

Disintegrin and metalloproteinase domain-containing protein 20 is an enzyme that in humans is encoded by the ADAM20 gene. It is a membrane disintegrin-metalloprotease that belongs to the ADAM family. It is exclusively expressed in Testes and is similar to sperm cell-specific fertilins -alpha and -beta.

Gamma-glutamyltransferase 6 is a protein that in humans is encoded by the GGT6 gene.

Major facilitator superfamily domain containing 14A is a protein that in humans is encoded by the MFSD14A gene. MFSD14A is an atypical solute carrier of MFS type. HGNC:23363

Copine 7 is a protein that in humans is encoded by the CPNE7 gene.

Diacylglycerol O-acyltransferase 2 (DGAT2) is a protein that in humans is encoded by the DGAT2 gene.

FERM and PDZ domain containing 2 is a protein that in humans is encoded by the FRMPD2 gene.

Solute carrier family 38 member 5 is a protein that in humans is encoded by the SLC38A5 gene.

Lysocardiolipin acyltransferase 1 is a protein that in humans is encoded by the LCLAT1 gene.

Immunoglobulin superfamily member 3 is a protein that in humans is encoded by the IGSF3 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000143797 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020646 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Membrane bound O-acyltransferase domain containing 2" . Retrieved 2017-05-24.

Membrane bound o-acyltransferase domain containing 2

Related Research Articles

References

Further reading