Meniscal cartilage replacement therapy

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Meniscal cartilage replacement therapy
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Head of right tibia seen from above, showing menisci and attachments of ligaments
Left knee-joint from behind, showing interior ligaments Gray348.png
Left knee-joint from behind, showing interior ligaments

Meniscal cartilage replacement therapy is surgical replacement of the meniscus of the knee as a treatment for where the meniscus is so damaged that it would otherwise need to be removed.

Contents

Anatomy

The meniscus is a C-shaped piece of fibrocartilage located at the peripheral aspect of the knee joint that offers lubrication and nutrition to the joint. Each knee has two menisci, medial and lateral, whose purpose is to provide space between the tibia and the femur, preventing friction and allowing for the diffusion of articular cartilage.[ citation needed ]

The majority of the meniscus has no blood supply. As a result, if the meniscus is damaged, from trauma or with age, it is unable to undergo the body’s normal healing process. Therefore, a torn piece can begin to move inside the joint, get caught between the bones, and cause pain, swelling, and decreased mobility. However, recent research has called into question whether many meniscus tears actually cause pain or are simply part of the normal degenerative process of aging. A 2008 study in the New England Journal of Medicine which shows that about 60% of meniscus tears cause no pain and are found in asymptomatic subjects. [1] The three major treatments for a damaged meniscus are repair, removal, and transplantation. The surgery is often carried out arthroscopically.[ citation needed ]

Repair

During repair, the tissues are securely held together long enough for biological healing to occur. One procedure involves threading long needles into the meniscus and out an incision in the back of the knee through the aid of a guide tube called a cannula. The suture thread ends are tied together on the outside of the knee capsule layer to bring the tear together. Another procedure requires specially designed devices that employ multiple sutures and knot pusher instruments to allow surgeons to provide excellent meniscal repair with just a single 1 ½” incision.[ citation needed ]

The majority of meniscal tears are not suitable for repair and instead the torn piece is removed, known as a meniscectomy. The torn portion of the meniscus is cut and sucked out of the joint, leaving behind as much normal meniscal cartilage as possible. The remaining meniscal rim is then rebalanced and contoured to provide a mechanically optimal shape.

Replacement

In some cases, the meniscal tear is so extensive that the entire meniscus must be removed, leaving the joint prone to constant pain and swelling. Removal of the meniscus cartilage leads to progressive, degenerative arthritis of the knee joint. Replacing the badly damaged or deficient meniscus with a meniscus transplant from a human donor restores normal knee structure and helps protect the remaining joint surfaces. Meniscal transplantation is relatively uncommon, although it is gaining popularity. Meniscal transplantation was previously indicated for patients with mild arthritis who are younger than 50 years of age. The population for whom meniscal transplantation is appropriate has expanded. Survival data from a recent, long-term follow-up study shows that meniscal transplantation is also successful in older, arthritic patients with a success rate of 89.4% (42 of 47 transplants) at an average of 4.4 years. Meniscal transplantation offers patients with badly damaged cartilage an alternative to total joint replacement, and allows patients to pursue active lifestyles including impact sports.[ citation needed ]

See also

Related Research Articles

Knee Region around the kneecap

In humans and other primates, the knee joins the thigh with the leg and consists of two joints: one between the femur and tibia, and one between the femur and patella. It is the largest joint in the human body. The knee is a modified hinge joint, which permits flexion and extension as well as slight internal and external rotation. The knee is vulnerable to injury and to the development of osteoarthritis.

Arthroscopy

Arthroscopy is a minimally invasive surgical procedure on a joint in which an examination and sometimes treatment of damage is performed using an arthroscope, an endoscope that is inserted into the joint through a small incision. Arthroscopic procedures can be performed during ACL reconstruction.

Shoulder problem Medical condition

Shoulder problems including pain, are one of the more common reasons for physician visits for musculoskeletal symptoms. The shoulder is the most movable joint in the body. However, it is an unstable joint because of the range of motion allowed. This instability increases the likelihood of joint injury, often leading to a degenerative process in which tissues break down and no longer function well.

Bakers cyst Medical condition

A Baker's cyst, also known as a popliteal cyst, is a type of fluid collection behind the knee. Often there are no symptoms. If symptoms do occur these may include swelling and pain behind the knee, or knee stiffness. If the cyst breaks open, pain may significantly increase with swelling of the calf. Rarely complications such as deep vein thrombosis, peripheral neuropathy, ischemia, or compartment syndrome may occur.

Meniscal cyst is a well-defined cystic lesion located along the peripheral margin of the meniscus, a part of the knee, nearly always associated with horizontal meniscal tears.

Meniscus (anatomy)

A meniscus is a crescent-shaped fibrocartilaginous anatomical structure that, in contrast to an articular disc, only partly divides a joint cavity. In humans they are present in the knee, wrist, acromioclavicular, sternoclavicular, and temporomandibular joints; in other animals they may be present in other joints.

The McMurray test, also known as the McMurray circumduction test is used to evaluate individuals for tears in the meniscus of the knee. A tear in the meniscus may cause a pedunculated tag of the meniscus which may become jammed between the joint surfaces.

A meniscus transplant or meniscal transplant is a transplant of the meniscus of the knee, which separates the thigh bone (femur) from the lower leg bone (tibia). The worn or damaged meniscus is removed and is replaced with a new one from a donor. The meniscus to be transplanted is taken from a cadaver, and, as such, is known as an allograft. Meniscal transplantation is technically difficult, as it must be sized accurately for each person, positioned properly and secured to the tibial plateau. As of 2012, only a few surgeons have significant volume of experience in meniscus transplantation worldwide.

Medial meniscus

The medial meniscus is a fibrocartilage semicircular band that spans the knee joint medially, located between the medial condyle of the femur and the medial condyle of the tibia. It is also referred to as the internal semilunar fibrocartilage. The medial meniscus has more of a crescent shape while the lateral meniscus is more circular. The anterior aspects of both menisci are connected by the transverse ligament. It is a common site of injury, especially if the knee is twisted.

Lateral meniscus

The lateral meniscus is a fibrocartilaginous band that spans the lateral side of the interior of the knee joint. It is one of two menisci of the knee, the other being the medial meniscus. It is nearly circular and covers a larger portion of the articular surface than the medial. It can occasionally be injured or torn by twisting the knee or applying direct force, as seen in contact sports.

The knee examination, in medicine and physiotherapy, is performed as part of a physical examination, or when a patient presents with knee pain or a history that suggests a pathology of the knee joint.

Unhappy triad Medical condition of the knee

The unhappy triad, also known as a blown knee among other names, is an injury to the anterior cruciate ligament, medial collateral ligament, and meniscus. Analysis during the 1990s indicated that this 'classic' O'Donoghue triad is actually an unusual clinical entity among athletes with knee injuries. Some authors mistakenly believe that in this type of injury, "combined anterior cruciate and medial collateral ligament disruptions that were incurred during athletic endeavors" always present with concomitant medial meniscus injury. However, the 1990 analysis showed that lateral meniscus tears are more common than medial meniscus tears in conjunction with sprains of the ACL.

Meniscus tear Rupturing of the fibrocartilage strips in the knee called menisci

A tear of a meniscus is a rupturing of one or more of the fibrocartilage strips in the knee called menisci. When doctors and patients refer to "torn cartilage" in the knee, they actually may be referring to an injury to a meniscus at the top of one of the tibiae. Menisci can be torn during innocuous activities such as walking or squatting. They can also be torn by traumatic force encountered in sports or other forms of physical exertion. The traumatic action is most often a twisting movement at the knee while the leg is bent. In older adults, the meniscus can be damaged following prolonged 'wear and tear'. Especially acute injuries can lead to displaced tears which can cause mechanical symptoms such as clicking, catching, or locking during motion of the joint. The joint will be in pain when in use, but when there is no load, the pain goes away.

The aim of an articular cartilage repair treatment is to restore the surface of an articular joint's hyaline cartilage. Over the last decades, surgeons and researchers have made progress in elaborating surgical cartilage repair interventions. Though these solutions do not perfectly restore articular cartilage, some of the latest technologies start to bring very promising results in repairing cartilage from traumatic injuries or chondropathies. These treatments are especially targeted by patients who suffer from articular cartilage damage. They provide pain relief while at the same time slowing down the progression of damage or considerably delaying joint replacement surgery. Articular cartilage repair treatments help patients to return to their original lifestyle; regaining mobility, going back to work and even practicing sports again.

Cartilage structures and functions can be damaged. Such damage can result from a variety of causes, such as a bad fall or traumatic sport-accident, previous knee injuries or wear and tear over time. Immobilization for long periods can also result in cartilage damage.

Discoid meniscus

Discoid meniscus is a rare human anatomic variant that usually affects the lateral meniscus of the knee. Usually a person with this anomaly has no complaints; however, it may present as pain, swelling, or a snapping sound heard from the affected knee. Strong suggestive findings on magnetic resonance imaging includes a thickened meniscal body seen on more than two contiguous sagittal slices.

Kevin Robert Stone, M.D. is a physician, orthopedic surgeon, clinician, researcher, and company founder of The Stone Clinic and the Stone Research Foundation in San Francisco.

The Stone Clinic

The Stone Clinic is a sports medicine clinic in San Francisco, California, offering orthopaedic surgery and medical care, physical therapy and rehabilitation, and radiology imaging services. The Stone Clinic was founded by Kevin R. Stone, M.D., an orthopaedic surgeon, combining himself with a team of nurses, physical therapists, imaging specialists, and patient coordinators, in 1988 to focus on caring for injured athletes and people experiencing arthritis pain.

Knee pain Medical condition

Knee pain is pain in or around the knee.

Cartilage repair techniques are the current focus of large amounts of research. Many different strategies have been proposed as solutions for cartilage defects. Surgical techniques currently being studied include:

References

  1. Martin Englund, M.D., Ph.D., Ali Guermazi, M.D., Daniel Gale, M.D., David J. Hunter, M.B.,B.S., Ph.D., Piran Aliabadi, M.D., Margaret Clancy, M.P.H., and David T. Felson, M.D., M.P.H.; et al. (September 2008). "Incidental Meniscal Findings on Knee MRI in Middle-Aged and Elderly Persons". N. Engl. J. Med. 359 (11): 1108–1115. doi:10.1056/NEJMoa0800777. PMC   2897006 . PMID   18784100.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  • “Meniscal Transplants.” The American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org. March 2003.
  • Sapega, Alexander. “Meniscus Repair vs. Removal.” The Knee and Shoulder Centers of New Jersey and Pennsylvania.
  • Pinkowski, John. “Meniscal Transplantation – A good choice for relieving pain and restoring mobility.” Orthopaedic and Rehabilitation Outlook :Quarterly. Fall Quarter 2004.
  • Stone KR, Walgenbach AW, Turek TJ, Freyer A, Hill MD. “Meniscus allograft survival in patients with moderate to severe unicompartmental arthritis: a 2- to 7-year follow-up.” Arthroscopy. 2006 May;22(5):469-78.