Methadone intermediate

Last updated
Methadone intermediate
Methadone Intermediate Structure.svg
Clinical data
Routes of
administration 		N/A
ATC code
  • none
Legal status
Legal status
Identifiers
  • 4-cyano-2-dimethylamino-4,4-diphenylbutane
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.004.324 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C19H22N2
Molar mass 278.399 g·mol−1
3D model (JSmol)
  • CC(CC(C#N)(C1=CC=CC=C1)C2=CC=CC=C2)N(C)C
  • InChI=1S/C19H22N2/c1-16(21(2)3)14-19(15-20,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-13,16H,14H2,1-3H3
  • Key:GJJQIGFCGLPOQK-UHFFFAOYSA-N

Methadone intermediate (pre-methadone, methadone nitrile, dimethylaminodiphenylbutanonitrile) is a methadone precursor scheduled by UN Single Convention on Narcotic Drugs. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9254. The 2014 annual manufacturing quota was 32 875 kilos. [3] It is listed as a Schedule I drug in Canada, [4] but is only significant as a precursor for methadone, as it does not have analgesic activity in its own right, though it does show some atropine-like activity. [5]

See also

References

  1. ↑ "STANDARD FOR THE UNIFORM SCHEDULING OF MEDICINES AND POISONS". Federal Register of Legislation. October 2020. Archived from the original on 2021-01-25. Retrieved 2021-08-15.
  2. ↑ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  3. ↑ "Quotas - Conversion Factors for Controlled Substances". Archived from the original on 2016-03-02. Retrieved 2016-02-28.
  4. ↑ "Controlled Drugs and Substances Act (S.C. 1996, c. 19)". Justice Laws Website. Government of Canada. 24 November 2023.
  5. ↑ Janssen PA (1960). "VII Nitriles". Diphenylpropylamines. Synthetic Analgesics. Vol. 1. Pergamon Press. pp. 122–128. LCCN   59-13814.


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