Methylenomycin B

Last updated
Methylenomycin B
Methylenomycin B.svg
Methylenomycin B 3D ball.png
Names
IUPAC name
2,3-Dimethyl-5-methylene-2-cyclopenten-1-one
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
UNII
  • InChI=1S/C8H10O/c1-5-4-6(2)8(9)7(5)3/h2,4H2,1,3H3 Yes check.svgY
    Key: YDXIEAHUYZKJOH-UHFFFAOYSA-N Yes check.svgY
  • InChI=1/C8H10O/c1-5-4-6(2)8(9)7(5)3/h2,4H2,1,3H3
    Key: YDXIEAHUYZKJOH-UHFFFAOYAN
  • O=C/1\C(=C)CC(=C\1C)\C
Properties
C8H10O
Molar mass 122.167 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Yes check.svgY  verify  (what is  Yes check.svgYX mark.svgN ?)

Methylenomycin B is a cyclopentanone derived antibiotic produced by Streptomyces coelicolor A3(2) that is effective against both Gram-negative and Gram-positive bacteria. [1] [2] It is the decarboxylated analog of methylenomycin C.

See also

References

  1. Brian P, Riggle PJ, Santos RA, Champness WC (June 1996). "Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system". J. Bacteriol. 178 (11): 3221–31. doi:10.1128/jb.178.11.3221-3231.1996. PMC   178074 . PMID   8655502.
  2. Hobbs G, Obanye AI, Petty J, et al. (March 1992). "An integrated approach to studying regulation of production of the antibiotic methylenomycin by Streptomyces coelicolor A3(2)". J. Bacteriol. 174 (5): 1487–94. doi:10.1128/jb.174.5.1487-1494.1992. PMC   206543 . PMID   1537793.