Interstate 110 (I-110) is a 4.1-mile (6.6 km) freeway spur route in Biloxi, Mississippi, running south from I-10 to U.S. Route 90 (US 90). It is one of very few places on the Interstate Highway System utilizing a drawbridge. The southbound control city is Biloxi, with a series of bridges out over the Gulf of Mexico at the southern terminus. There is no northbound control city; the road is marked with trailblazers reading "TO I-10" instead. It ran entirely concurrently with Mississippi Highway 15 (MS 15), until MS 15 was truncated to I-10.
Mississippi Highway 365 is a state highway in northeastern Mississippi. The route starts at MS 30 in Burton and travels northward. It travels into Burnsville and intersects U.S. Route 72. MS 365 continues northeastward and ends at MS 25 west of Pickwick Lake. The route was designated by 1950, connecting from MS 30 to MS 364. It was extended northward to MS 356 around 1958 and was completely paved by 1964. The route replaced parts of MS 356 in 1965, and its northern terminus was changed to MS 25.
Mississippi Highway 172 (MS 172) is a state highway located in Tishomingo County, Mississippi. The route runs 12.074 mi (19.431 km) from U.S. Route 72 (US 72) near Burnsville east to US 72 near Oldham, just west of the Alabama border. The route is a two-lane undivided road its entire length and runs mostly through wooded areas. It also passes through the town of Iuka, where it has an intersection with MS 25.
Mississippi Highway 145 (MS 145) is the designation for the parts of the old U.S. Route 45 (US 45) roadbed that the state continues to maintain or has designated. Those ten sections travel through Waynesboro, near Boice, through Shubuta, from De Soto to Meridian, through Shuqualak, through Macon, through Aberdeen, through Nettleton, from Shannon to Booneville, and through Corinth.
Mississippi Highway 555 is a state highway in southwestern Mississippi. The route has two sections, both in Adams County. The first section starts at Ogden Road and travels northwestward to its terminus at US 61. The second section starts at the concurrency of MS 930 and MS 932 and the concurrency of US 61 and US 84 in Natchez. MS 555 travels northward through Pine Ridge and ends at Anna's Bottom Road near the Anna site. The route travels by a few historical locations, including the Pine Ridge Presbyterian Church.
Mississippi Highway 23 is a state highway in Mississippi. The route starts at MS 25 in the town of Smithville. It travels northeastward through the forests of eastern Itawamba County. The highway intersects Interstate 22 (I-22) and U.S. Route 78 in Tremont. MS 23 ends at the Mississippi–Alabama state line, just west of Red Bay.
Interstate 10 (I-10), a major east–west Interstate Highway in the southern areas of the United States, has a section of about 77 miles (124 km) in Mississippi.
Mississippi Highway 53 is a state highway in Mississippi. The highway starts at U.S. Highway 49 in Gulfport and travels northwestward to MS 603 in Hancock County. The road then travels north to Poplarville, meeting Interstate 59 (I-59). MS 53 ends at MS 26 and US 11 in southwestern Poplarville. The road that became MS 53 has existed since 1928, and the highway was designated in 1950. The highway was completely paved by 1957, and an interchange was created at I-59 in 1967.
Mississippi Highway 311 is a state highway located in Marshall County, Mississippi, United States. The route runs 12.960 mi (20.857 km) from MS 7 in Holly Springs north to U.S. Route 72 in Mount Pleasant. The route is a two-lane undivided road its entire length and passes through rural areas. MS 311 was designated onto its current alignment in 1957, and was fully paved from a gravel road by the 1960s.
Mississippi Highway 306 is a state highway in northern Mississippi. The route starts at U.S. Route 51 in Coldwater, and it travels eastward to an interchange at Interstate 55 (I-55) on the northern edge of the town. The road continues eastward across northern Tate County and ends at MS 305 near Independence. MS 306 was designated in 1952, and it was constructed in 1953 from US 51 to MS 305. The route was paved in asphalt by 1956, and an interchange was built at I-55 by 1967.
Mississippi Highway 198 is a state highway in the U.S. state of Mississippi. The highway is the designation for six former segments of U.S. Highway 98 that have been bypassed by newer alignments. These six segments are located in Tylertown, Columbia, Hattiesburg, Beaumont, McLain, and Lucedale. Five of the six sections of MS 198 are two-lane undivided roads that pass through small towns; the exception is the Hattiesburg section which is a four-lane divided highway running through developed areas of the city. The total length of the six sections of MS 198 is 24.937 miles (40.132 km).
Mississippi Highway 607 is a state highway in the Mississippi Gulf Coast region. The route starts at U.S. Route 90, and it travels westward to Interstate 10 (I-10). The route has a gap as the road travels through the Stennis Space Center, but resumes north of the center to end at I-59 and US 11 south of Picayune. The road was part of US 11 and US 90, before MS 43 was designated in 1948. MS 607 was created in 1967, after MS 43 was rerouted, and Stennis Space Center was built.
Mississippi Highway 161 (MS 161) is a state highway designation for three highways in the U.S. state of Mississippi, consisting of old alignments of U.S. Route 61 (US 61). Totaling at 19.872 miles (31.981 km), the three sections are located in Bolivar, Coahoma, and Desoto counties. The Bolivar County section, designated in 2000, travels from Merigold to Mound Bayou and Shelby. In Coahoma County, MS 161 was designated in 2004 and runs through Clarksdale and Lyon. In Desoto County, MS 161 travels through the town of Walls and was created in 1999.
Mississippi Highway 332 is a highway in central Mississippi. Its western terminus is at U.S. Route 51 in Grenada. The route travels northeastward through farmland to Grenada Municipal Airport. The road continues to its eastern terminus at Toe Road, southwest of the Grenada Lake. The designation was created in 1958 for a former segment of MS 7, which was rerouted north of the lake.
Mississippi Highway 617 is a short unsigned state highway in southern Mississippi. Its southern terminus is in the Port of Pascagoula. The route then travels north for nearly two mi (3.2 km) and ends at U.S. Route 90. The road was constructed in 1973, and an interchange was added at US 90 around 1993. MS 617 was designated on July 1, 2002, and no significant changes were made since.
Mississippi Highway 844 is a short highway near Crystal Springs, Mississippi. The route starts at Interstate 55 (I-55), and connects to U.S. Route 51 (US 51) east of the interstate highway. The road that became MS 844 was constructed around 1967, and was hidden in maps by 1974. Instead, a new loop near Crystal Springs was created. The route reappeared by 1998, and the section of MS 844 east of US 51 was transferred to the county by 2005.
Mississippi Highway 500 is a short state highway in central Mississippi. The route starts at MS 13 in the town of Lena, and it travels eastward across southern Leake County. The road turns northeastward after halfway to its eastern terminus, and it ends at MS 487 near Tuscola. MS 500 was designated in 1960 as a gravel road, and it was completely paved with asphalt eight years later.
Mississippi Highway 603 is a 25.0-mile-long (40.2 km) state highway in Hancock County, Mississippi. The highway generally runs north–south from its southern terminus at U.S. Route 90 (US 90) in Waveland through Bay St. Louis and Kiln to its northern terminus at MS 53 near Necaise. The road is maintained by the Mississippi Department of Transportation (MDOT). MDOT and Mississippi's law code define MS 603's southern terminus as its intersection with MS 43 in Kiln. However, many maps such as Google Maps and MapQuest, and local signage show the highway continuing farther south to Waveland.' The road that became MS 603 has existed since 1927, and the highway was designated in 1950. The highway was also partially paved, from Waveland to Kiln, in 1950 and was completely paved in 1957. An interchange was created at Interstate 10 (I-10) in 1960.
Mississippi Highway 382 is a state highway in eastern Mississippi. The route starts at U.S. Route 45 Alternate near Prairie and travels eastward. The road travels through farmland as it reaches Prairie. MS 382 then ends at MS 25 near Aberdeen. The road was constructed around 1951 from MS 45W west of Prairie to US 45 in Aberdeen, and it was designated by 1958. The eastern terminus was changed to MS 25 from US 45 by 1967.
Mississippi Highway 389 is a state highway that runs from south to north in the U.S. State of Mississippi. MS 389 currently exists in two sections. The southern section begins at MS 182 in Starkville. The road travels north out of the city, and crosses U.S. Route 82 and MS 15. North of Starkville, the route continues northwestwards and ends at the Oktibbeha–Clay county line south of Pheba. The northern section starts at MS 46 west of Montpelier, and it travels north to cross the Natchez Trace Parkway in Chickasaw County. MS 389 ends at MS 8 in Houston.
US 90 in Gulfport 
