Route 126 is a highway located entirely within Barton County in the U.S. state of Missouri. Its western terminus is at the Kansas state line, where K-126 ends. The route goes in a straight line for most of its length, and intersects Interstate 49 (I-49) and U.S. Route 71. Its eastern terminus is at US 160 and Route 37 in Golden City. The route was designated in 1942, and formerly consisted of two supplemental routes.
Route 101 is a short highway in southern Missouri. The route starts at Arkansas Highway 101 at the Arkansas–Missouri state line, and travels northeastward. It travels through the city of Bakersfield, intersecting Route 142. The road then continues north to its northern terminus at U.S. Route 160 in Caulfield. The route was designated in 1941, after a supplementary route was renumbered.
Route 19 is a long state highway in Missouri. Its northern terminus is at U.S. Route 61 in New London and its southern terminus is at U.S. Route 63 on the north side of Thayer. Route 19 is one of Missouri's original 1922 highways, though it initially had a northern terminus at Route 14 in Cuba and was later extended north.
Route 164 is a state highway in the Missouri Bootheel. The route starts at U.S. Route 412 in Cardwell. The route travels eastward across the bootheel, and it goes through the towns of Arbyrd, Hornersville, Rives, and Steele. It becomes concurrent with US 61 briefly in Steele, and intersects Interstate 55 (I-55) east of the city. The route ends east of Cottonwood Point, near the Mississippi River.
Route 108 is a short highway in the Bootheel of southeastern Missouri. Its eastern terminus is the Arkansas state line at Arkansas Highway 77, about six miles (10 km) south of Arbyrd, the only town on the route. Its western terminus is at U.S. Route 412 (US 412) about two miles (3 km) north of Arbyrd. Although signed as an east–west route, the route follows mostly north–south roadways. The route was designated in 1930, and was extended east in 1972.
Route 246 is a 15.002-mile-long (24.143 km) east–west highway in extreme northern Missouri. The western terminus is at Route 148 in Hopkins. The route travels eastward to supplemental Route E, where it becomes concurrent and starts traveling south. It then continues east to its terminus at Route 46 east of Sheridan. Formerly a spur route of Route 46 and supplemental Route D, Route 246 was designated around 1954, and was extended west to Hopkins in 1955.
Route 16 is a 16.709-mile-long (26.891 km) highway in Lewis County, Missouri. The western terminus is at Route 6 east of Lewistown. The route travels eastward, through Monticello and over a few rivers. Route 16 then intersects U.S. Route 61. The route ends at US 61 Business and Route B in Canton. The road was formerly part of Route 6, but it was rerouted in 1931. The old alignment was renumbered Route 96 that year. Ten years later, the route was renumbered to Route 16.
Highway 43 is a designation for three north–south state highways in Arkansas. One segment of 27.1 miles (43.6 km) runs from Highway 264 in Siloam Springs north into Delaware County, Oklahoma along Oklahoma State Highway 20 (SH-20) to terminate at Missouri Route 43 (Route 43) at the Missouri/Oklahoma/Arkansas tri-point near Southwest City, Missouri. A second segment of 20.0 miles (32.2 km) runs northeast from Highway 21 at Boxley to Highway 7 in Harrison. The third segment runs 1.8 miles (2.9 km) north in Harrison from US Route 65 (US 65) to Highway 7.
Route 102 is a highway in southeastern Missouri. The route starts at Route 105 near East Prairie. It travels southeastwards through farmland to Big Oak Tree State Park. The road then turns east past the entrance to the park, and ends at its eastern terminus at Route 77 in Dorena. The route was designated in 1940, as a road from the state park to a supplemental route. Route 102 replaced a large section of the supplemental route in 1961, and then was extended eastwards to a new terminus at Route 77 in 1994.
Route 162 is a state highway in the Missouri Bootheel. Its western terminus is at Route 25 in Clarkton, Dunklin County, and the route travels eastward to nearby towns of Gideon and Portageville, where it intersects U.S. Route 61 and Interstate 55 (I-55). The road then continues through rural New Madrid County and ends at a boat ramp near the Mississippi River.
Route 106 is a highway in the southern part of the US State of Missouri. Its eastern terminus is at Route 21 at Ellington; its western terminus is at Route 17 in Summersville. Route 106 runs through the eastern, mountainous Ozarks and through two sections of the Ozark National Scenic Riverways.
Route 48 is a state highway in northwestern Missouri. Its western terminus is located at U.S. Route 71 north of Savannah. The route travels eastward across the communities of Rosendale, Rea, and Whitesville. The road ends at US 169 in King City, about 20 miles (32 km) from its western terminus. The road was designated around 1926, and was completely laid down with gravel by 1936 and paved in asphalt by 1942.
Route 75 is a short highway in Mississippi County in the U.S. state of Missouri. Its southern terminus is at Route 80, and it travels north through farmland to the town of Anniston. It then travels westward to its northern terminus at Route 105 north of East Prairie. The route was designated in 1968, after Route 77 was moved to a new alignment east of Anniston, and the remaining section was renumbered to Route 75.
Highway 5 is a designation for three state highways in Arkansas. The southern segment of 40.20 miles (64.70 km) runs from Highway 7 in Hot Springs north to Interstate 430 (I-430) and US Highway 70 (US 70) in Little Rock.
Arkansas Highway 23 is a north–south state highway in north Arkansas. The route runs 129.88 miles (209.02 km) from US 71 near Elm Park north to the Missouri state line through Ozark and Eureka Springs. Between AR 16 at Brashears and Interstate 40 north of Ozark, Highway 23 winds through the Ozark National Forest and is designated as the Pig Trail Scenic Byway due to its steep hills and hairpin turns. The route has a strong connection with the University of Arkansas Razorbacks, connecting fans in Central Arkansas with the Northwest Arkansas area.
Highway 21 is a north–south state highway in north central Arkansas. The route of 99.14 miles (159.55 km) runs from US Route 64 (US 64) in Clarksville north across US 62 to Missouri Route 13 at the Missouri state line The route is a two-lane highway with the exception of a brief concurrency with US 62, a four-lane highway, in Berryville.
Highway 87 is a designation for four north–south state highways in Arkansas. Created during the 1926 Arkansas state highway numbering, the original alignment remains between Bradford and Pleasant Plains, though it has been revised and extended over the years. The three remaining segments are former county roads, connecting rural communities to local points of interest and other state highways. All three were added to the state highway system in 1973 during a period of system expansion. All segments are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 103 is a designation for two north–south state highways in Arkansas. One segment begins in Clarksville in the Arkansas River Valley and runs north to the Ozark National Forest. A second route runs through a sparsely populated segment of the Ozark Mountains between the Buffalo National River and Highway 21 near the Missouri state line.
Highway 14 is an east–west state highway in Arkansas. The route of 227.35 miles (365.88 km) begins at Boat Dock Road near Table Rock Lake and runs east to Mississippi County Route W1020 (CR W1020) at Golden Lake. Segments of the highway are part of two Arkansas Scenic Byways: Sylamore Scenic Byway in the Ozark National Forest and the Crowley's Ridge Parkway atop Crowley's Ridge.
Route 84 is a state highway in the Missouri bootheel. The route starts at Arkansas Highway 90 over the St. Francis River on the Arkansas–Missouri state line. The road travels eastward to Kennett, where it becomes concurrent with U.S. Route 412. East of Kennett, the concurrent routes travel eastward on a divided highway to Hayti Heights, where the concurrency ends. Route 84 travels through Hayti Heights and Hayti, and it crosses Interstate 55 (I-55) and US 61. The route then travels southeastwards to Caruthersville, and bypasses the central area of the city. In the southern part of Caruthersville, Route 84 ends at an interchange with I-155 and US 412.
Route Z at the Ozark National Scenic Riverways 
US 60 near Van Buren 
