Mitoguardin 1

MIGA1
Identifiers
Aliases	MIGA1 , FAM73A, family with sequence similarity 73 member A, mitoguardin 1
External IDs	OMIM: 616773 MGI: 1924567 HomoloGene: 18369 GeneCards: MIGA1
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p31.1 Start 77,779,624 bp [1] End 77,879,539 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 H3 Start 151,979,486 bp [2] End 152,046,044 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell Brodmann area 23 pancreatic epithelial cell pons subthalamic nucleus inferior ganglion of vagus nerve external globus pallidus corpus callosum Brodmann area 46 medulla oblongata Top expressed in dorsomedial hypothalamic nucleus ventral tegmental area pontine nuclei dorsal tegmental nucleus lateral hypothalamus medial vestibular nucleus mammillary body piriform cortex superior colliculus medial dorsal nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding protein homodimerization activity protein heterodimerization activity Cellular component mitochondrial outer membrane integral component of membrane mitochondrion membrane integral component of plasma membrane Biological process mitochondrial fusion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 374986 215708 Ensembl ENSG00000180488 ENSMUSG00000054942 UniProt Q8NAN2 Q4QQM5 RefSeq (mRNA) NM_001270384 NM_198549 NM_001363583 NM_001363584 NM_001363586 NM_001162375 NM_174868 RefSeq (protein) NP_001257313 NP_940951 NP_001350512 NP_001350513 NP_001350515 NP_001155847 NP_777357 Location (UCSC) Chr 1: 77.78 – 77.88 Mb Chr 3: 151.98 – 152.05 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Mitoguardin 1 is a protein that in humans is encoded by the MIGA1 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000180488 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000054942 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Mitoguardin 1" . Retrieved 2016-08-16.

Further reading

• Zhang Y, Liu X, Bai J, Tian X, Zhao X, Liu W, Duan X, Shang W, Fan HY, Tong C (2016). "Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis". Mol. Cell. 61 (1): 111–24. doi: 10.1016/j.molcel.2015.11.017 . PMID   26711011.