| MOSPD1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | MOSPD1 , DJ473B4, Motile sperm domain containing 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 300674 MGI: 1917630 HomoloGene: 128711 GeneCards: MOSPD1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Motile sperm domain containing 1 is a protein that in humans is encoded by the MOSPD1 gene. [5]
Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.
AT-rich interactive domain-containing protein 3B is a protein that in humans is encoded by the ARID3B gene.
Homeobox protein Meis2 is a protein that in humans is encoded by the MEIS2 gene.
Thioredoxin domain-containing protein 5 is a protein that in humans is encoded by the TXNDC5 gene.
SUN domain-containing protein 5, formerly known as sperm-associated antigen 4-like protein (SPAGL4), is a protein that in humans is encoded by the SUN5 gene.
Disintegrin and metalloproteinase domain-containing protein 18 is an enzyme that in humans is encoded by the ADAM18 gene.
Centrosomal protein of 120 kDa (Cep120), also known as coiled-coil domain-containing protein 100, is a protein that in humans is encoded by the CEP120 gene.
Dynein axonemal intermediate chain 2 also known as axonemal dynein intermediate chain 2, is a protein that in humans is encoded by the DNAI2 gene.
Intraflagellar transport protein 80 homolog (IFT80), also known as WD repeat-containing protein 56, is a protein that in humans is encoded by the IFT80 gene.
Disintegrin and metalloproteinase domain-containing protein 7 is a protein that in humans is encoded by the ADAM7 gene. ADAM7 is an 85-kDa enzyme that is a member of the transmembrane ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM7 is important for the maturation of sperm cells in mammals. ADAM7 is also denoted as: ADAM_7, ADAM-7, EAPI, GP-83, and GP83.
Motile sperm domain containing 2 is a protein that in humans is encoded by the MOSPD2 gene. It is an endoplasmic reticulum–resident protein involved in membrane contact site formation. Its domain homologous to Major Sperm Protein is very similar to VAPA/VAPB, so it has been described as the third human member of the VAP protein family.
Motile sperm domain containing 3 is a protein that in humans is encoded by the MOSPD3 gene.
Coiled-coil domain containing 151 is a protein that in humans is encoded by the CCDC151 gene.
Disintegrin and metalloproteinase domain-containing protein 20 is an enzyme that in humans is encoded by the ADAM20 gene. It is a membrane disintegrin-metalloprotease that belongs to the ADAM family. It is exclusively expressed in Testes and is similar to sperm cell-specific fertilins -alpha and -beta.
Jumonji domain containing 1C is a protein that in humans is encoded by the JMJD1C gene.
V-set and immunoglobulin domain containing 4 is a protein that in humans is encoded by the VSIG4 gene.
Pacer is a protein that in humans is encoded by the RUBCNL gene. Pacer has been shown to increase cellular autophagy through regulation of PI3KC3.
Methylsterol monooxygenase 1 is a protein that in humans is encoded by the MSMO1 gene.
Alcohol dehydrogenase, iron containing 1 is a protein that in humans is encoded by the ADHFE1 gene.
Coiled-coil domain-containing protein 181 (CCDC181) is a protein that in human is encoded by C1orf114, which is located at the Chromosome 1 at 1q24.2. The accession is Q5T1D7. Researches have recently revealed that CCDC 181 is a microtubule-binding protein that interacts with murine Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia. The disruption of Hook1 may lead to inappropriate function of spermatogenesis. The dysfunction may be related to the abnormal head shape of sperm or distinctive structural changes in flagella in sperm, which can result in male infertility. An increased rate of my gene has found in the haploid phase of male cell during meiosis, thus it is believed to relate to sperm cell and aid in spermatogenesis.
