Nucleoporin NDC1 is a protein that in humans is encoded by the TMEM48 gene. [5] [6] [7] It anchors aladin to the nuclear pore complex. [8]
Nucleoporin NDC1 is a protein that in humans is encoded by the TMEM48 gene. [5] [6] [7] It anchors aladin to the nuclear pore complex. [8]
Nucleoporin p62 (p62) is a protein complex associated with the nuclear envelope. The p62 protein remains associated with the nuclear pore complex-lamina fraction. p62 is synthesized as a soluble cytoplasmic precursor of 61 kDa followed by modification that involve addition of N-acetylglucosamine residues, followed by association with other complex proteins.
Nucleoporins are a family of proteins which are the constituent building blocks of the nuclear pore complex (NPC). The nuclear pore complex is a massive structure embedded in the nuclear envelope at sites where the inner and outer nuclear membranes fuse, forming a gateway that regulates the flow of macromolecules between the cell nucleus and the cytoplasm. Nuclear pores enable the passive and facilitated transport of molecules across the nuclear envelope. Nucleoporins, a family of around 30 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nucleoporin 62 is the most abundant member of this family. Nucleoporins are able to transport molecules across the nuclear envelope at a very high rate. A single NPC is able to transport 60,000 protein molecules across the nuclear envelope every minute.
Nucleoporin 153 (Nup153) is a protein which in humans is encoded by the NUP153 gene. It is an essential component of the basket of nuclear pore complexes (NPCs) in vertebrates, and required for the anchoring of NPCs. It also acts as the docking site of an importing karyopherin. On the cytoplasmic side of the NPC, Nup358 fulfills an analogous role.
Nucleoporin 214 (Nup2014) is a protein that in humans is encoded by the NUP214 gene.
AladinTM, also known as adracalin, is a nuclear envelope protein that in humans is encoded by the AAAS gene. It is named after the achalasia–addisonianism–alacrima syndrome which occurs when the gene is mutated.
Nucleoporin 88 (Nup88) is a protein that in humans is encoded by the NUP88 gene.
Thyroid hormone receptor-associated protein 3 is a protein that in humans is encoded by the THRAP3 gene.
Nucleoporin 50 (Nup50) is a protein that in humans is encoded by the NUP50 gene.
Nucleoporin 107 (Nup107) is a protein that in humans is encoded by the NUP107 gene.
Nucleoporin 54 (Nup54) is a protein that in humans is encoded by the NUP54 gene.
Nucleoporin 133 (Nup133) is a protein that in humans is encoded by the NUP133 gene.
Nuclear envelope pore membrane protein POM 121 is a protein that in humans is encoded by the POM121 gene. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Nucleoporin 160 (Nup160) is a protein that in humans is encoded by the NUP160 gene.
Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene.
Nucleoporin 155 (Nup155) is a protein that in humans is encoded by the NUP155 gene.
Transmembrane and coiled-coil domain-containing protein 1 is a protein that in humans is encoded by the TMCO1 gene.
Nucleoporin 93 (Nup93) is a protein that in humans is encoded by the NUP93 gene.
Nucleoporin p58/p45 is a protein that in humans is encoded by the NUPL1 gene.
Nucleoporin 35 (Nup35) is a protein that in humans is encoded by the NUP35 gene.
Protein ELYS is a protein that in humans is encoded by the AHCTF1 gene.
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