NDFIP1

Last updated
NDFIP1
Identifiers
Aliases NDFIP1 , N4WBP5, Nedd4 family interacting protein 1
External IDs OMIM: 612050 MGI: 1929601 HomoloGene: 12730 GeneCards: NDFIP1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030571

NM_022996
NM_001355749

RefSeq (protein)

NP_085048

NP_075372
NP_001342678

Location (UCSC) Chr 5: 142.11 – 142.15 Mb Chr 18: 38.41 – 38.47 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Nedd4 family interacting protein 1 is a protein that in humans is encoded by the NDFIP1 gene. [5]

Contents

Function

The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008].

Related Research Articles

NEDD4

E3 ubiquitin-protein ligase NEDD4, also known as neural precursor cell expressed developmentally down-regulated protein 4 is an enzyme that is, in humans, encoded by the NEDD4 gene.

NEDD4L

Neural precursor cell expressed developmentally downregulated gene 4-like (NEDD4L) or NEDD4-2 is an enzyme of the NEDD4 family. In human the protein is encoded by the NEDD4L gene. In mouse the protein is commonly known as NEDD4-2 and the gene Nedd4-2.

PIAS4

E3 SUMO-protein ligase PIAS4 is one of several protein inhibitor of activated STAT (PIAS) proteins. It is also known as protein inhibitor of activated STAT protein gamma, and is an enzyme that in humans is encoded by the PIAS4 gene.

Arrestin beta 1

Arrestin, beta 1, also known as ARRB1, is a protein which in humans is encoded by the ARRB1 gene.

Protein inhibitor of activated STAT2

E3 SUMO-protein ligase PIAS2 is an enzyme that in humans is encoded by the PIAS2 gene.

UBE2L3

Ubiquitin-conjugating enzyme E2 L3 (UBE2L3), also called UBCH7, is a protein that in humans is encoded by the UBE2L3 gene. As an E2 enzyme, UBE2L3 participates in ubiquitination to target proteins for degradation. The role of UBE2L3 in the ubiquitination of the NF-κB precursor implicated it in various major autoimmune diseases, including rheumatoid arthritis (RA), celiac disease, Crohn's disease(CD), and systemic lupus erythematosus.

CUL2

Cullin-2 is a protein that in humans is encoded by the CUL2 gene.

UBE2D1

Ubiquitin-conjugating enzyme E2 D1 is a protein that in humans is encoded by the UBE2D1 gene.

UBE2G2

Ubiquitin-conjugating enzyme E2 G2 is a protein that in humans is encoded by the UBE2G2 gene.

UBE1C

NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene.

UBE2L6

Ubiquitin/ISG15-conjugating enzyme E2 L6 is a protein that in humans is encoded by the UBE2L6 gene.

AP1G2

AP-1 complex subunit gamma-like 2 is a protein that in humans is encoded by the AP1G2 gene.

WWP2

NEDD4-like E3 ubiquitin-protein ligase WWP2 also known as atrophin-1-interacting protein 2 (AIP2) or WW domain-containing protein 2 (WWP2) is an enzyme that in humans is encoded by the WWP2 gene.

RNF19A

E3 ubiquitin-protein ligase RNF19A is an enzyme that in humans is encoded by the RNF19A gene.

UBE2E1

Ubiquitin-conjugating enzyme E2 E1 is a protein that in humans is encoded by the UBE2E1 gene.

ARIH1

Protein ariadne-1 homolog is a protein that in humans is encoded by the ARIH1 gene.

UBE2M

NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene.

SENP8

Sentrin-specific protease 8 is an enzyme that in humans is encoded by the SENP8 gene.

NDFIP2

NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene.

WBP1

WW domain-binding protein 1 is a protein that in humans is encoded by the WBP1 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000131507 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024425 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Nedd4 family interacting protein 1" . Retrieved 2017-10-18.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.