NDOR1

NDOR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4H2D
Identifiers
Aliases	NDOR1 , NR1, bA350O14.9, NADPH dependent diflavin oxidoreductase 1, CIAE1
External IDs	OMIM: 606073 MGI: 1926047 HomoloGene: 7144 GeneCards: NDOR1
Gene location (Human)
Chr.	Chromosome 9 (human)
End	137,219,361 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; spleen; ; right uterine tube; ; left lobe of thyroid gland; ; body of stomach; ; tibial nerve; ; right adrenal gland; ; gastric mucosa; ; left uterine tube; ; skin of abdomen;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity ; FMN binding ; NADPH-hemoprotein reductase activity ; protein binding ; flavin adenine dinucleotide binding ; NADP binding ; oxidoreductase activity, acting on NAD(P)H ;
Cellular component	cytoplasm ; perinuclear region of cytoplasm ; cytosol ; intermediate filament cytoskeleton ; nucleus ;
Biological process	cell death ; cellular response to menadione ; iron-sulfur cluster assembly ;
	Sources:Amigo / QuickGO
Orthologs
	27158
	78797
	ENSG00000188566
	ENSMUSG00000006471
	Q9UHB4
	A2AI05
	NM_001144026 ; NM_001144027 ; NM_001144028 ; NM_014434
	NM_001082476 ; NM_001252541 ; NM_001252542 ; NM_178239
	NP_001137498 ; NP_001137499 ; NP_001137500 ; NP_055249
	NP_001075945 ; NP_001239470 ; NP_001239471
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 04, 2023

NADPH-dependent diflavin oxidoreductase 1 is an enzyme that in humans is encoded by the NDOR1 gene.^[4]^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000188566 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Paine MJ, Garner AP, Powell D, Sibbald J, Sales M, Pratt N, Smith T, Tew DG, Wolf CR (Feb 2000). "Cloning and characterization of a novel human dual flavin reductase". J Biol Chem. 275 (2): 1471–8. doi: 10.1074/jbc.275.2.1471 . PMID 10625700.
↑ Finn RD, Basran J, Roitel O, Wolf CR, Munro AW, Paine MJ, Scrutton NS (Mar 2003). "Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1". Eur J Biochem. 270 (6): 1164–75. doi: 10.1046/j.1432-1033.2003.03474.x . PMID 12631275.
↑ "Entrez Gene: NDOR1 NADPH dependent diflavin oxidoreductase 1".

Kwasnicka DA, Krakowiak A, Thacker C, et al. (2003). "Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1". J. Biol. Chem. 278 (40): 39051–8. doi: 10.1074/jbc.M306355200 . PMC 2556063 . PMID 12871939.
Olteanu H, Banerjee R (2003). "Redundancy in the pathway for redox regulation of mammalian methionine synthase: reductive activation by the dual flavoprotein, novel reductase 1". J. Biol. Chem. 278 (40): 38310–4. doi: 10.1074/jbc.M306282200 . PMID 12871938.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Kornau HC, Schenker LT, Kennedy MB, Seeburg PH (1995). "Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95". Science. 269 (5231): 1737–40. Bibcode:1995Sci...269.1737K. doi:10.1126/science.7569905. PMID 7569905.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000188566 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10625700-4] Paine MJ, Garner AP, Powell D, Sibbald J, Sales M, Pratt N, Smith T, Tew DG, Wolf CR (Feb 2000). "Cloning and characterization of a novel human dual flavin reductase". J Biol Chem. 275 (2): 1471–8. doi: 10.1074/jbc.275.2.1471 . PMID 10625700.

[pmid12631275-5] Finn RD, Basran J, Roitel O, Wolf CR, Munro AW, Paine MJ, Scrutton NS (Mar 2003). "Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1". Eur J Biochem. 270 (6): 1164–75. doi: 10.1046/j.1432-1033.2003.03474.x . PMID 12631275.

[entrez-6] "Entrez Gene: NDOR1 NADPH dependent diflavin oxidoreductase 1".

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NDOR1

Related Research Articles

References

Further reading