NFRKB

NFRKB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3U21, 4UF6, 4WLP
Identifiers
Aliases	NFRKB , INO80G, nuclear factor related to kappaB binding protein
External IDs	OMIM: 164013 MGI: 2442410 HomoloGene: 4492 GeneCards: NFRKB
Gene location (Human)
Chr.	Chromosome 11 (human)
End	129,895,590 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	31,332,629 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; endothelial cell; ; left lobe of thyroid gland; ; right uterine tube; ; right lobe of thyroid gland; ; testicle; ; skin of abdomen; ; vagina; ; gastrocnemius muscle; ; body of pancreas;
	Top expressed in
	secondary oocyte; ; superior cervical ganglion; ; hand; ; otolith organ; ; utricle; ; medullary collecting duct; ; spermatocyte; ; thymus; ; fossa; ; cumulus cell;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protease binding ; DNA binding ; protein binding ;
Cellular component	nucleus ; Ino80 complex ; nucleoplasm ;
Biological process	DNA recombination ; inflammatory response ; regulation of transcription, DNA-templated ; transcription by RNA polymerase II ; DNA repair ; transcription, DNA-templated ; cellular response to DNA damage stimulus ; protein deubiquitination ;
	Sources:Amigo / QuickGO
Orthologs
	4798
	235134
	ENSG00000170322
	ENSMUSG00000042185
	Q6P4R8
	Q6PIJ4
	NM_001143835 ; NM_006165
	NM_172766 ; NM_001359654
	NP_001137307 ; NP_006156 ; NP_001137307.1
NP_766354 ; NP_001346583 ; NP_001392026 ; NP_001392027 ; NP_001392028 ;
	NP_001392030 ; NP_001392031
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Nuclear factor related to kappa-B-binding protein is a protein that in humans is encoded by the NFRKB gene.^[5]^[6]

Related Research Articles

Myb-binding protein 1A is a protein that in humans is encoded by the MYBBP1A gene.

LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene.

Thyroid hormone receptor-associated protein 3 is a protein that in humans is encoded by the THRAP3 gene.

Ribonuclease P protein subunit p20 is an enzyme that in humans is encoded by the POP7 gene.

Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex.

Anaphase-promoting complex subunit 1 is an enzyme that in humans is encoded by the ANAPC1 gene.

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, also known as NFKBIE, is a protein which in humans is encoded by the NFKBIE gene.

Nucleoporin 160 (Nup160) is a protein that in humans is encoded by the NUP160 gene.

Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene.

Probable ATP-dependent RNA helicase DDX41 is an enzyme that in humans is encoded by the DDX41 gene.

Periodic tryptophan protein 1 homolog is a protein that in humans is encoded by the PWP1 gene.

MORC family CW-type zinc finger protein 2 is a protein that in humans is encoded by the MORC2 gene.

Condensin-2 complex subunit D3 (CAP-D3) also known as non-SMC condensin II complex subunit D3 (NCAPD3) is a protein that, in humans, is encoded by the NCAPD3 gene. CAP-D3 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

Kinetochore-associated protein NSL1 homolog is a protein that in humans is encoded by the NSL1 gene.

ESF1 homolog is a protein that in humans is encoded by the ESF1 gene.

Nucleoporin NDC1 is a protein that in humans is encoded by the TMEM48 gene. It anchors aladin to the nuclear pore complex.

Zinc finger protein 22 is a protein that in humans is encoded by the ZNF22 gene.

Putative splicing factor, arginine/serine-rich 14 is a protein that in humans is encoded by the SFRS14 gene.

Protein ELYS is a protein that in humans is encoded by the AHCTF1 gene.

Microfibrillar-associated protein 1 is a protein that in humans is encoded by the MFAP1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000170322 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042185 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Adams BS, Leung K, Meltzer PS, Lewis KA, Wagner-McPherson C, Evans GA, Nabel GJ (Dec 1992). "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25" (PDF). Genomics. 14 (2): 270–4. doi:10.1016/S0888-7543(05)80216-2. hdl: 2027.42/29810 . PMID 1427843.
↑ "Entrez Gene: NFRKB nuclear factor related to kappaB binding protein".

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC 1459365 . PMID 16565220.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC 514446 . PMID 15302935.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Urban MB, Schreck R, Baeuerle PA (1991). "NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit". EMBO J. 10 (7): 1817–25. doi:10.1002/j.1460-2075.1991.tb07707.x. PMC 452856 . PMID 2050119.
Adams BS, Leung KY, Hanley EW, Nabel GJ (1992). "Cloning of R kappa B, a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site". New Biol. 3 (11): 1063–73. PMID 1777480.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000170322 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042185 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1427843-5] Adams BS, Leung K, Meltzer PS, Lewis KA, Wagner-McPherson C, Evans GA, Nabel GJ (Dec 1992). "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25" (PDF). Genomics. 14 (2): 270–4. doi:10.1016/S0888-7543(05)80216-2. hdl: 2027.42/29810 . PMID 1427843.

[entrez-6] "Entrez Gene: NFRKB nuclear factor related to kappaB binding protein".

[1]

[2]

[3]

[4]

[5]

[6]

NFRKB

Related Research Articles

References

Further reading