NFRKB

NFRKB
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3U21, 4UF6, 4WLP
Identifiers
Aliases	NFRKB , INO80G, nuclear factor related to kappaB binding protein
External IDs	OMIM: 164013; MGI: 2442410; HomoloGene: 4492; GeneCards: NFRKB; OMA:NFRKB - orthologs
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q24.3 Start 129,863,636 bp [1] End 129,895,590 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A4 Start 31,297,488 bp [2] End 31,332,629 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell secondary oocyte testicle endothelial cell left lobe of thyroid gland right uterine tube right lobe of thyroid gland gonad skin of leg left ovary Top expressed in secondary oocyte superior cervical ganglion primary oocyte hand otolith organ zygote utricle medullary collecting duct spermatocyte thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protease binding DNA binding protein binding Cellular component nucleus Ino80 complex nucleoplasm Biological process DNA recombination inflammatory response regulation of transcription, DNA-templated transcription by RNA polymerase II DNA repair transcription, DNA-templated cellular response to DNA damage stimulus protein deubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4798 235134 Ensembl ENSG00000170322 ENSMUSG00000042185 UniProt Q6P4R8 Q6PIJ4 RefSeq (mRNA) NM_001143835 NM_006165 NM_172766 NM_001359654 RefSeq (protein) NP_001137307 NP_006156 NP_001137307.1 NP_766354 NP_001346583 NP_001392026 NP_001392027 NP_001392028 NP_001392030 NP_001392031 Location (UCSC) Chr 11: 129.86 – 129.9 Mb Chr 9: 31.3 – 31.33 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Nuclear factor related to kappa-B-binding protein is a protein that in humans is encoded by the NFRKB gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000170322 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042185 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Adams BS, Leung K, Meltzer PS, Lewis KA, Wagner-McPherson C, Evans GA, Nabel GJ (Dec 1992). "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25" (PDF). Genomics. 14 (2): 270–4. doi:10.1016/S0888-7543(05)80216-2. hdl: 2027.42/29810 . PMID   1427843.
6. "Entrez Gene: NFRKB nuclear factor related to kappaB binding protein".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC   1459365 . PMID   16565220.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Urban MB, Schreck R, Baeuerle PA (1991). "NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit". EMBO J. 10 (7): 1817–25. doi:10.1002/j.1460-2075.1991.tb07707.x. PMC   452856 . PMID   2050119.
• Adams BS, Leung KY, Hanley EW, Nabel GJ (1992). "Cloning of R kappa B, a novel DNA-binding protein that recognizes the interleukin-2 receptor alpha chain kappa B site". New Biol. 3 (11): 1063–73. PMID   1777480.