NOSIP

NOSIP
Identifiers
Aliases	NOSIP , CGI-25, nitric oxide synthase interacting protein
External IDs	OMIM: 616759 MGI: 1913644 HomoloGene: 9315 GeneCards: NOSIP
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,590,262 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,727,634 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; triceps brachii muscle; ; blood; ; gastrocnemius muscle; ; sperm; ; vastus lateralis muscle; ; lymph node; ; spleen; ; canal of the cervix; ; amniotic fluid;
	Top expressed in
	spermatid; ; spermatocyte; ; interventricular septum; ; lip; ; blastocyst; ; internal carotid artery; ; morula; ; yolk sac; ; external carotid artery; ; seminiferous tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ; transferase activity ; RNA binding ; ubiquitin protein ligase activity ;
Cellular component	cytoplasm ; cytosol ; Golgi membrane ; nucleus ;
Biological process	negative regulation of catalytic activity ; negative regulation of nitric-oxide synthase activity ; multicellular organism development ; protein ubiquitination ; regulation of nitric-oxide synthase activity ;
	Sources:Amigo / QuickGO
Orthologs
	51070
	66394
	ENSG00000142546
	ENSMUSG00000003421
	Q9Y314
	Q9D6T0
	NM_001270960 ; NM_015953 ; NM_001363649
	NM_001163684 ; NM_025533
	NP_001257889 ; NP_057037 ; NP_001350578
	NP_001157156 ; NP_079809
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 30, 2022

Nitric oxide synthase-interacting protein is an enzyme that in humans is encoded by the NOSIP gene.^[5]^[6]^[7]

Related Research Articles

Elongation factor Tu, mitochondrial is a protein that in humans is encoded by the TUFM gene. It is an EF-Tu homolog.

DnaJ homolog subfamily B member 9 is a protein that in humans is encoded by the DNAJB9 gene.

3'-5' exoribonuclease CSL4 homolog is an enzyme that in humans is encoded by the EXOSC1 gene.

Ribonuclease P protein subunit p30 is an enzyme that in humans is encoded by the RPP30 gene.

Putative RNA-binding protein Luc7-like 2 is a protein that in humans is encoded by the LUC7L2 gene.

60S ribosomal protein L18 is a protein that in humans is encoded by the RPL18 gene.

Glutathione peroxidase 7 is an enzyme that in humans is encoded by the GPX7 gene.

Cavin-2 or Serum deprivation-response protein (SDPR) is a protein that in humans is encoded by the SDPR gene. Cavin-2 is highly expressed in a variety of human endothelial cells.

Polymerase delta-interacting protein 3 is an enzyme that in humans is encoded by the POLDIP3 gene.

NF-kappa-B-repressing factor is a protein that in humans is encoded by the NKRF gene.

Hedgehog interacting protein (HHIP) is a protein that in humans is encoded by the HHIP gene.

Endothelial cell-selective adhesion molecule is a protein that in humans is encoded by the ESAM gene.

Zinc finger protein 267 is a protein that in humans is encoded by the ZNF267 gene.

cAMP-dependent protein kinase inhibitor gamma is a protein that in humans is encoded by the PKIG gene.

Hepatoma-derived growth factor, related protein 3, also known as HDGFRP3, is a human gene.

RRP15-like protein is a protein that in humans is encoded by the RRP15 gene.

Copper homeostasis protein cutC homolog is a protein that in humans is encoded by the CUTC gene.

rRNA-processing protein FCF1 homolog is a protein that in humans is encoded by the FCF1 gene.

RNA transcription, translation and transport factor is a protein that in humans is encoded by the RTRAF gene.

cAMP-dependent protein kinase inhibitor beta is a protein that in humans is encoded by the PKIB gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000142546 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000003421 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Dedio J, Konig P, Wohlfart P, Schroeder C, Kummer W, Muller-Esterl W (Jan 2001). "NOSIP, a novel modulator of endothelial nitric oxide synthase activity". FASEB J. 15 (1): 79–89. doi:10.1096/fj.00-0078com. PMID 11149895. S2CID 34485514.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.
↑ "Entrez Gene: NOSIP nitric oxide synthase interacting protein".

Schleicher M, Brundin F, Gross S, et al. (2005). "Cell cycle-regulated inactivation of endothelial NO synthase through NOSIP-dependent targeting to the cytoskeleton". Mol. Cell. Biol. 25 (18): 8251–8. doi:10.1128/MCB.25.18.8251-8258.2005. PMC 1234313 . PMID 16135813.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Dreyer J, Schleicher M, Tappe A, et al. (2005). "Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity". J. Neurosci. 24 (46): 10454–65. doi: 10.1523/JNEUROSCI.2265-04.2004 . PMC 6730309 . PMID 15548660.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000142546 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000003421 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11149895-5] Dedio J, Konig P, Wohlfart P, Schroeder C, Kummer W, Muller-Esterl W (Jan 2001). "NOSIP, a novel modulator of endothelial nitric oxide synthase activity". FASEB J. 15 (1): 79–89. doi:10.1096/fj.00-0078com. PMID 11149895. S2CID 34485514.

[pmid10810093-6] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.

[entrez-7] "Entrez Gene: NOSIP nitric oxide synthase interacting protein".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

NOSIP

Related Research Articles

References

Further reading