NOX1

Last updated
NOX1
Identifiers
Aliases NOX1 , GP91-2, MOX1, NOH-1, NOH1, NADPH oxidase 1, NOH-1L
External IDs OMIM: 300225; MGI: 2450016; HomoloGene: 48495; GeneCards: NOX1; OMA:NOX1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_013955
NM_001271815
NM_007052
NM_013954

NM_172203

RefSeq (protein)

NP_001258744
NP_008983
NP_039249

NP_757340

Location (UCSC) Chr X: 100.84 – 100.87 Mb Chr X: 132.99 – 133.12 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

NADPH oxidase 1 is an enzyme that in humans is encoded by the NOX1 gene. [5]

NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene. [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000007952 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031257 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Suh YA, Arnold RS, Lassegue B, Shi J, Xu X, Sorescu D, Chung AB, Griendling KK, Lambeth JD (Sep 1999). "Cell transformation by the superoxide-generating oxidase Mox1". Nature. 401 (6748): 79–82. Bibcode:1999Natur.401...79S. doi:10.1038/43459. PMID   10485709. S2CID   4365361.
  6. "Entrez Gene: NOX1 NADPH oxidase 1".

Further reading