NPM3

Last updated
NPM3
Identifiers
Aliases NPM3 , PORMIN, TMEM123, nucleophosmin/nucleoplasmin 3
External IDs OMIM: 606456 MGI: 894653 HomoloGene: 5083 GeneCards: NPM3
Orthologs
SpeciesHumanMouse
Entrez

10360

18150

Ensembl

ENSG00000107833

ENSMUSG00000056209

UniProt

O75607

Q9CPP0

RefSeq (mRNA)

NM_006993

NM_008723

RefSeq (protein)

NP_008924

NP_032749

Location (UCSC) Chr 10: 101.78 – 101.78 Mb Chr 19: 45.74 – 45.74 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Nucleoplasmin-3 is a protein that in humans is encoded by the NPM3 gene. [5] [6]

Contents

The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. It is highly homologous to the murine Npm3 gene. Based on the structural similarity of the human NPM3 gene product to nucleoplasmin and nucleophosmin, NPM3 may represent a new member of this gene family, and may share basic functions with the molecular chaperones. [6]

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000107833 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000056209 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Shackleford GM, Ganguly A, MacArthur CA (Jul 2003). "Cloning, expression and nuclear localization of human NPM3, a member of the nucleophosmin/nucleoplasmin family of nuclear chaperones". BMC Genomics. 2: 8. doi: 10.1186/1471-2164-2-8 . PMC   60000 . PMID   11722795.
  6. 1 2 "Entrez Gene: NPM3 nucleophosmin/nucleoplasmin, 3".

Further reading


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