NSMCE4A

NSMCE4A
Identifiers
Aliases	NSMCE4A , C10orf86, NS4EA, NSE4A, NSE4 homolog A, SMC5-SMC6 complex component
External IDs	OMIM: 612987; MGI: 1915122; HomoloGene: 9745; GeneCards: NSMCE4A; OMA:NSMCE4A - orthologs
Gene location (Human) Chr. Chromosome 10 (human) [1] Band 10q26.13 Start 121,957,091 bp [1] End 121,975,217 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 F3 Start 130,134,256 bp [2] End 130,174,848 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte gastric mucosa parotid gland body of pancreas muscle layer of sigmoid colon minor salivary glands rectum transverse colon body of uterus Top expressed in mandibular prominence endocardial cushion maxillary prominence epiblast abdominal wall medial ganglionic eminence ventricular zone hand migratory enteric neural crest cell atrioventricular valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component telomere Smc5-Smc6 complex nucleus chromosome nucleoplasm nuclear body Biological process DNA recombination DNA repair positive regulation of response to DNA damage stimulus cellular response to DNA damage stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54780 67872 Ensembl ENSG00000107672 ENSMUSG00000040331 UniProt Q9NXX6 n/a RefSeq (mRNA) NM_001167865 NM_017615 NM_001162855 RefSeq (protein) NP_001161337 NP_060085 n/a Location (UCSC) Chr 10: 121.96 – 121.98 Mb Chr 7: 130.13 – 130.17 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000107672 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000040331 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hu B, Liao C, Millson SH, Mollapour M, Prodromou C, Pearl LH, Piper PW, Panaretou B (Mar 2005). "Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex". Mol Microbiol. 55 (6): 1735–50. doi: 10.1111/j.1365-2958.2005.04531.x . PMID   15752197. S2CID   40645007.
6. "Entrez Gene: NSMCE4A non-SMC element 4 homolog A (S. cerevisiae)".

Further reading

• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi: 10.1073/pnas.0404089101 . PMC   524842 . PMID   15498874.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi: 10.1038/nature02462 . PMID   15164054.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.