NUFIP2

NUFIP2
Identifiers
Aliases	NUFIP2 , 182-FIP, 82-FIP, FIP-82, PIG1, FMR1 interacting protein 2, nuclear FMR1 interacting protein 2, NUFP2
External IDs	OMIM: 609356 MGI: 1915814 HomoloGene: 10808 GeneCards: NUFIP2
Gene location (Human)
Chr.	Chromosome 17 (human)
End	29,294,148 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	77,632,747 bp
RNA expression pattern
	Top expressed in
	caput epididymis; ; corpus epididymis; ; secondary oocyte; ; tibialis anterior muscle; ; spongy bone; ; pancreatic epithelial cell; ; deltoid muscle; ; Achilles tendon; ; placenta; ; endothelial cell;
	Top expressed in
	hand; ; body of femur; ; pineal gland; ; belly cord; ; secondary oocyte; ; foot; ; left colon; ; dermis; ; soleus muscle; ; tibialis anterior muscle;
	More reference expression data
	More reference expression data
Orthologs
	57532
	68564
	ENSG00000108256
	ENSMUSG00000037857
	Q7Z417
	Q5F2E7
	NM_020772
	NM_001024205
	NP_065823 ; NP_065823.1
	NP_001019376
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 07, 2024

Nuclear fragile X mental retardation-interacting protein 2 is a protein that in humans is encoded by the NUFIP2 gene.^[5]^[6]^[7]

Interactions

NUFIP2 has been shown to interact with FMR1 and Roquin-1.^[8]^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000108256 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037857 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 Bardoni B, Castets M, Huot ME, Schenck A, Adinolfi S, Corbin F, Pastore A, Khandjian EW, Mandel JL (Jul 2003). "82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization". Hum Mol Genet. 12 (14): 1689–98. doi: 10.1093/hmg/ddg181 . PMID 12837692.
↑ Ramos A, Hollingworth D, Adinolfi S, Castets M, Kelly G, Frenkiel TA, Bardoni B, Pastore A (Jan 2006). "The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction". Structure. 14 (1): 21–31. doi: 10.1016/j.str.2005.09.018 . PMID 16407062.
↑ "Entrez Gene: NUFIP2 nuclear fragile X mental retardation protein interacting protein 2".
↑ Rehage N (2018). "Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA". Nature Communications. 9 (1): 299. Bibcode:2018NatCo...9..299R. doi:10.1038/s41467-017-02582-1. PMC 5775257 . PMID 29352114.

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID 8889548.
Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi: 10.1093/dnares/7.1.65 . PMID 10718198.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi: 10.1016/j.cub.2004.07.051 . PMID 15324660. S2CID 2371325.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi: 10.1074/mcp.M400085-MCP200 . PMID 15345747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000108256 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037857 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12837692-5] 1 2 Bardoni B, Castets M, Huot ME, Schenck A, Adinolfi S, Corbin F, Pastore A, Khandjian EW, Mandel JL (Jul 2003). "82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization". Hum Mol Genet. 12 (14): 1689–98. doi: 10.1093/hmg/ddg181 . PMID 12837692.

[pmid16407062-6] Ramos A, Hollingworth D, Adinolfi S, Castets M, Kelly G, Frenkiel TA, Bardoni B, Pastore A (Jan 2006). "The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction". Structure. 14 (1): 21–31. doi: 10.1016/j.str.2005.09.018 . PMID 16407062.

[entrez-7] "Entrez Gene: NUFIP2 nuclear fragile X mental retardation protein interacting protein 2".

[8] Rehage N (2018). "Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA". Nature Communications. 9 (1): 299. Bibcode:2018NatCo...9..299R. doi:10.1038/s41467-017-02582-1. PMC 5775257 . PMID 29352114.

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NUFIP2

Contents

Interactions

Related Research Articles

References

Further reading