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Caenorhabditis elegans is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. It is the type species of its genus. The name is a blend of the Greek caeno- (recent), rhabditis (rod-like) and Latin elegans (elegant). In 1900, Maupas initially named it Rhabditides elegans. Osche placed it in the subgenus Caenorhabditis in 1952, and in 1955, Dougherty raised Caenorhabditis to the status of genus.
Genome projects are scientific endeavours that ultimately aim to determine the complete genome sequence of an organism and to annotate protein-coding genes and other important genome-encoded features. The genome sequence of an organism includes the collective DNA sequences of each chromosome in the organism. For a bacterium containing a single chromosome, a genome project will aim to map the sequence of that chromosome. For the human species, whose genome includes 22 pairs of autosomes and 2 sex chromosomes, a complete genome sequence will involve 46 separate chromosome sequences.
Crassostrea is a genus of true oysters containing some of the most important oysters used for food.
Gene knockdown is an experimental technique by which the expression of one or more of an organism's genes is reduced. The reduction can occur either through genetic modification or by treatment with a reagent such as a short DNA or RNA oligonucleotide that has a sequence complementary to either gene or an mRNA transcript.
Sir John Edward Sulston was a British biologist and academic who won the Nobel Prize in Physiology or Medicine for his work on the cell lineage and genome of the worm Caenorhabditis elegans in 2002 with his colleagues Sydney Brenner and Robert Horvitz at the MRC Laboratory of Molecular Biology. He was a leader in human genome research and Chair of the Institute for Science, Ethics and Innovation at the University of Manchester. Sulston was in favour of science in the public interest, such as free public access of scientific information and against the patenting of genes and the privatisation of genetic technologies.
Mitochondrial 5-demethoxyubiquinone hydroxylase, also known as coenzyme Q7, hydroxylase, is an enzyme that in humans is encoded by the COQ7 gene. The clk-1 (clock-1) gene encodes this protein that is necessary for ubiquinone biosynthesis in the worm Caenorhabditis elegans and other eukaryotes. The mouse version of the gene is called mclk-1 and the human, fruit fly and yeast homolog COQ7.
Caenorhabditis is a genus of nematodes which live in bacteria-rich environments like compost piles, decaying dead animals and rotting fruit. The name comes from Greek: caeno- ; rhabditis = rod-like.
Caenorhabditis brenneri is a small nematode, closely related to the model organism Caenorhabditis elegans. Its genome is being sequenced by Washington University in St. Louis Genome Sequencing Center. This species has previously been referred to as C. sp 4 and Caenorhabditis sp. CB5161, but was recently formally described and given its scientific name. This name is in honor of Sydney Brenner, recognizing his pioneering role in starting active research in the field of C. elegans biology and development.
Abiotrophia is a genus of lactic acid bacteria, a family in the phylum Bacillota (Bacteria).
28S ribosomal protein S33, mitochondrial is a protein that in humans is encoded by the MRPS33 gene.
Richard Michael Durbin is a British computational biologist and Al-Kindi Professor of Genetics at the University of Cambridge. He also serves as an associate faculty member at the Wellcome Sanger Institute where he was previously a senior group leader.
Caenorhabditis remanei is a species of nematode found in North America and Europe, and likely lives throughout the temperate world. Several strains have been developed in the laboratory.
Latrodectus elegans is a species of black widow spider, found in South Asia, Southeast Asia and East Asia. It was first collected by the Swedish arachnologist Tamerlan Thorell in the Karen Hills in Myanmar, but is also found in Thailand, India, Nepal, Vietnam, China and Japan. As of July 2022, the World Spider Catalog lists only India, Nepal, Myanmar, China and Japan. This species has been recorded in India and Nepal only since 2012, and Indochina in 2015, which is thought to reflect historical under-surveying of arachnids in this region.
WormBase is an online biological database about the biology and genome of the nematode model organism Caenorhabditis elegans and contains information about other related nematodes. WormBase is used by the C. elegans research community both as an information resource and as a place to publish and distribute their results. The database is regularly updated with new versions being released every two months. WormBase is one of the organizations participating in the Generic Model Organism Database (GMOD) project.
Caenorhabditis angaria is a small nematode, in the same genus as the model organism Caenorhabditis elegans. The name is from the Latin after the tendency to ride weevils. Prior to 2011, the species was referred to as C. sp. 2, C. sp. 3, and C. sp. PS1010. Its genome was sequenced at the California Institute of Technology in 2010. This species is gonochoristic. It has distinct morphology and behavior compared to C. elegans; notably, C. angaria males exhibit a spiral mating behavior. Its divergence from C. elegans is similar to the distance between humans and fish. C. castelli is its closest relative, and the two species can produce F1 hybrids.
Nematocida parisii is a parasitic species of Microsporidia fungi found in wild isolates of the common nematode, Caenorhabditis elegans. The fungus forms spores and replicates in the intestines before leaving the host.
Tc1/mariner is a class and superfamily of interspersed repeats DNA transposons. The elements of this class are found in all animals, including humans. They can also be found in protists and bacteria.
Caenorhabditis afra is a species of nematodes in the genus Caenorhabditis. This gonochoristic (male-female) species was isolated by Matthias Herrmann in Begoro, Ghana, Africa in 2007. Its genome is being sequenced at McDonnell Genome Institute at Washington University School of Medicine.
Semotivirus is the only genus of viruses in the family Belpaoviridae. Species exist as retrotransposons in a eukaryotic host's genome. BEL/pao transposons are only found in animals.
Holocentric chromosomes are chromosomes that possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes. They were first described in cytogenetic experiments in 1935. Since this first observation, the term holocentric chromosome has referred to chromosomes that: i) lack the primary constriction corresponding to the centromere observed in monocentric chromosomes; and ii) possess multiple kinetochores dispersed along the entire chromosomal axis, such that microtubules bind to the chromosome along its entire length and move broadside to the pole from the metaphase plate. Holocentric chromosomes are also termed holokinetic, because, during cell division, the sister chromatids move apart in parallel and do not form the classical V-shaped figures typical of monocentric chromosomes.
References
- ↑ Cuomo, C. A.; Desjardins, C. A.; Bakowski, M. A.; Goldberg, J.; Ma, A. T.; Becnel, J. J.; Didier, E. S.; Fan, L.; Heiman, D. I.; Levin, J. Z.; Young, S.; Zeng, Q.; Troemel, E. R. (2012-07-18). "Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth". Genome Research. 22 (12). Cold Spring Harbor Laboratory: 2478–2488. doi: 10.1101/gr.142802.112 . ISSN 1088-9051. PMC 3514677 .
