Neurogenin-1 is a protein that in humans is encoded by the NEUROG1 gene. [5] [6]
NEUROG1 has been shown to interact with CREB-binding protein [7] and decapentaplegic homolog 1. [7]
Neuronal migration protein doublecortin, also known as doublin or lissencephalin-X is a protein that in humans is encoded by the DCX gene.
Neurogenic differentiation 1 (Neurod1), also called β2, is a transcription factor of the NeuroD-type. It is encoded by the human gene NEUROD1.
Retinoid X receptor gamma (RXR-gamma), also known as NR2B3 is a nuclear receptor that in humans is encoded by the RXRG gene.
Probable G-protein coupled receptor 37 is a protein that in humans is encoded by the GPR37 gene. GPR37 is primarily found in the central nervous system (CNS), with significant expression observed in various CNS regions including the amygdala, basal ganglia, substantia nigra, hippocampus, frontal cortex, and hypothalamus, particularly noteworthy is its exceptionally elevated expression in the spinal cord.
Taste receptor type 2 member 4 is a protein that in humans is encoded by the TAS2R4 gene.
Taste receptor type 2 member 13 is a protein that in humans is encoded by the TAS2R13 gene.
Taste receptor type 2 member 7 is a protein that in humans is encoded by the TAS2R7 gene.
Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene.
Growth arrest and DNA-damage-inducible, beta, also known as GADD45B, is a protein which in humans is encoded by the GADD45B gene.
Ephrin-A2 is a protein that in humans is encoded by the EFNA2 gene.
Ubiquitin-conjugating enzyme E2 variant 1 is a protein that in humans is encoded by the UBE2V1 gene.
Homeobox protein Hox-D11 is a protein that in humans is encoded by the HOXD11 gene.
Homeobox protein Hox-D12 is a protein that in humans is encoded by the HOXD12 gene.
Neurogenins, often abbreviated as Ngn, are a family of bHLH transcription factors involved in specifying neuronal differentiation. The family consisting of Neurogenin-1, Neurogenin-2, and Neurogenin-3, plays a fundamental role in specifying neural precursor cells and regulating the differentiation of neurons during embryonic development. It is one of many gene families related to the atonal gene in Drosophila. Other positive regulators of neuronal differentiation also expressed during early neural development include NeuroD and ASCL1.
Neurogenic differentiation factor 2 is a protein that in humans is encoded by the NEUROD2 gene.
Homeobox protein EMX1 is a protein that in humans is encoded by the EMX1 gene. The transcribed EMX1 gene is a member of the EMX family of transcription factors. The EMX1 gene, along with its family members, are expressed in the developing cerebrum. EMX1 plays a role in specification of positional identity, the proliferation of neural stem cells, differentiation of layer-specific neuronal phenotypes and commitment to a neuronal or glial cell fate.
Gliogenesis is the generation of non-neuronal glia populations derived from multipotent neural stem cells.
Neurogenin-2 is a protein that in humans is encoded by the NEUROG2 gene.
Neurogenin-3 (NGN3) is a protein that in humans is encoded by the Neurog3 gene.
Proneural genes encode transcription factors of the basic helix-loop-helix (bHLH) class which are responsible for the development of neuroectodermal progenitor cells. Proneural genes have multiple functions in neural development. They integrate positional information and contribute to the specification of progenitor-cell identity. From the same ectodermal cell types, neural or epidermal cells can develop based on interactions between proneural and neurogenic genes. Neurogenic genes are so called because loss of function mutants show an increase number of developed neural precursors. On the other hand, proneural genes mutants fail to develop neural precursor cells.