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Eugenics is a set of beliefs and practices that aim to improve the genetic quality of a human population. Historically, eugenicists have attempted to alter the frequency of various human phenotypes by inhibiting the fertility of people and groups they considered inferior, or promoting that of those considered superior.
Bioethics is both a field of study and professional practice, interested in ethical issues related to health, including those emerging from advances in biology, medicine, and technologies. It proposes the discussion about moral discernment in society and it is often related to medical policy and practice, but also to broader questions as environment, well-being and public health. Bioethics is concerned with the ethical questions that arise in the relationships among life sciences, biotechnology, medicine, politics, law, theology and philosophy. It includes the study of values relating to primary care, other branches of medicine, ethical education in science, animal, and environmental ethics, and public health.
Preimplantation genetic diagnosis is the genetic profiling of embryos prior to implantation, and sometimes even of oocytes prior to fertilization. PGD is considered in a similar fashion to prenatal diagnosis. When used to screen for a specific genetic disease, its main advantage is that it avoids selective abortion, as the method makes it highly likely that the baby will be free of the disease under consideration. PGD thus is an adjunct to assisted reproductive technology, and requires in vitro fertilization (IVF) to obtain oocytes or embryos for evaluation. Embryos are generally obtained through blastomere or blastocyst biopsy. The latter technique has proved to be less deleterious for the embryo, therefore it is advisable to perform the biopsy around day 5 or 6 of development.
Human genetic enhancement or human genetic engineering refers to human enhancement by means of a genetic modification. This could be done in order to cure diseases, prevent the possibility of getting a particular disease, to improve athlete performance in sporting events, or to change physical appearance, metabolism, and even improve physical capabilities and mental faculties such as memory and intelligence. These genetic enhancements may or may not be done in such a way that the change is heritable.
Sex selection is the attempt to control the sex of the offspring to achieve a desired sex. It can be accomplished in several ways, both pre- and post-implantation of an embryo, as well as at childbirth. It has been marketed under the title family balancing.
Surrogacy is an arrangement, often supported by a legal agreement, whereby a woman agrees to pregnancy and childbirth on behalf of (an)other person(s) who will become the child's legal parent(s) after birth. People pursue surrogacy for a variety of reasons such as infertility, dangers or undesirable factors of pregnancy, or when pregnancy is a medical impossibility.
A designer baby is a baby whose genetic makeup has been selected or altered, often to exclude a particular gene or to remove genes associated with disease. This process usually involves analysing a wide range of human embryos to identify genes associated with particular diseases and characteristics, and selecting embryos that have the desired genetic makeup; a process known as preimplantation genetic diagnosis. Screening for single genes is commonly practiced, and polygenic screening is offered by a few companies. Other methods by which a baby's genetic information can be altered involve directly editing the genome before birth, which is not routinely performed and only one instance of this is known to have occurred as of 2019, where Chinese twins Lulu and Nana were edited as embryos, causing widespread criticism.
Human enhancement is the natural, artificial, or technological alteration of the human body in order to enhance physical or mental capabilities.
Julian Savulescu is an Australian philosopher and bioethicist. He is Chen Su Lan Centennial Professor in Medical Ethics and Director of the Centre for Biomedical Ethics at the Yong Loo Lin School of Medicine, National University of Singapore. He is also the Uehiro Chair in Practical Ethics at the University of Oxford, and was previously the Fellow of St Cross College, Oxford, Director of the Oxford Uehiro Centre for Practical Ethics, and co-director of the Wellcome Centre for Ethics and Humanities. He is a visiting professorial fellow in Biomedical Ethics at the Murdoch Children's Research Institute in Australia, and distinguished visiting professor in Law at Melbourne University since 2017. He directs the Biomedical Ethics Research Group and is a member of the Centre for Ethics of Pediatric Genomics in Australia. He is a former editor and current board member of the Journal of Medical Ethics, which is ranked as the No.2 journal in bioethics worldwide by Google Scholar Metrics, as of 2022. In addition to his background in applied ethics and philosophy, he also has a background in medicine and neuroscience and completed his MBBS (Hons) and BMedSc at Monash University, graduating top of his class with 18 of 19 final year prizes in Medicine. He edits the Oxford University Press book series, the Uehiro Series in Practical Ethics.
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In bioethics, the ethics of cloning concerns the ethical positions on the practice and possibilities of cloning, especially of humans. While many of these views are religious in origin, some of the questions raised are faced by secular perspectives as well. Perspectives on human cloning are theoretical, as human therapeutic and reproductive cloning are not commercially used; animals are currently cloned in laboratories and in livestock production.
The genetics and abortion issue is an extension of the abortion debate and the disability rights movement. Since the advent of forms of prenatal diagnosis, such as amniocentesis and ultrasound, it has become possible to detect the presence of congenital disorders in the fetus before birth. Specifically, disability-selective abortion is the abortion of fetuses that are found to have non-fatal mental or physical defects detected through prenatal testing. Many prenatal tests are now considered routine, such as testing for Down syndrome. Women who are discovered to be carrying fetuses with disabilities are often faced with the decision of whether to abort or to prepare to parent a child with disabilities.
A savior baby,savior sibling, or donor baby is a child who is conceived in order to provide a stem cell transplant to a sibling that is affected with a fatal disease, such as cancer or Fanconi anemia, that can best be treated by hematopoietic stem cell transplantation.
Eugenics, the set of beliefs and practices which aims at improving the genetic quality of the human population, played a significant role in the history and culture of the United States from the late 19th century into the mid-20th century. The cause became increasingly promoted by intellectuals of the Progressive Era.
The history of eugenics is the study of development and advocacy of ideas related to eugenics around the world. Early eugenic ideas were discussed in Ancient Greece and Rome. The height of the modern eugenics movement came in the late 19th and early 20th centuries.
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Bioconservatism is a philosophical and ethical stance that emphasizes caution and restraint in the use of biotechnologies, particularly those involving genetic manipulation and human enhancement. The term "bioconservatism" is a portmanteau of the words biology and conservatism.
Moral enhancement, also called moral bioenhancement, is the use of biomedical technology to morally improve individuals. MBE is a growing topic in neuroethics, a field developing the ethics of neuroscience as well as the neuroscience of ethics. After Thomas Douglas introduced the concept of MBE in 2008, its merits have been widely debated in academic bioethics literature. Since then, Ingmar Persson and Julian Savulescu have been among the most vocal MBE supporters. Much of the debate over MBE has focused on Persson and Savulescu's 2012 book in support of it, Unfit for the Future? The Need for Moral Enhancement.
Despite its political failure under the Third Republic, Eugenics in France experienced early and thorough theoretical development. This medical eugenics ideology advocated for the formation of a human elite under the guidance of the French state as early as the late 18th century. Subsequent awareness of the theories of British anthropologist and statistician Francis Galton, the first theorist of eugenics, led to the creation of the French Society of Eugenics in 1913.
References
- ↑ Agar N (2004). Liberal Eugenics: In Defence of Human Enhancement. Wiley. ISBN 1-4051-2390-7.
- ↑ Goering, Sara (2 July 2014). "Eugenics". Stanford Encyclopedia of Philosophy. Archived from the original on 29 November 2014.
- ↑ Black E (2003). War Against the Weak: Eugenics and America's Campaign to Create a Master Race . Four Walls Eight Windows. ISBN 1-56858-258-7. OCLC 1035882630.
- ↑ King, D. S. (1999-04-01). "Preimplantation genetic diagnosis and the 'new' eugenics". Journal of Medical Ethics. 25 (2): 176–182. doi:10.1136/jme.25.2.176. ISSN 0306-6800. PMC 479204 . PMID 10226925.
- 1 2 Hoffman, Allison K (2017-12-01). "Review of The New Eugenics: Selective Breeding in an Era of Reproductive Technologies". Journal of Law and the Biosciences. 4 (3): 671–7. doi:10.1093/jlb/lsx025. ISSN 2053-9711. PMC 5965496 .
- ↑ King DS (April 1999). "Preimplantation genetic diagnosis and the 'new' eugenics". Journal of Medical Ethics. 25 (2): 176–82. doi:10.1136/jme.25.2.176. PMC 479204 . PMID 10226925.
- 1 2 "Regulating Eugenics". Harvard Law Review. 2008. Retrieved May 2, 2015.
- ↑ Galton, DJ (2005-01-01). "Eugenics: some lessons from the past". Reproductive BioMedicine Online. 10: 133–6. doi:10.1016/S1472-6483(10)62222-5. ISSN 1472-6483. PMID 15820025.
- 1 2 Fox D (2007). "The Illiberality of Liberal Eugenics". Ratio. 20: 1–25. doi:10.1111/j.1467-9329.2007.00343.x. SSRN 1072104.
- ↑ International Bioethics Committee (October 2, 2015). "Report of the IBC on Updating Its Reflection on the Human Genome and Human Rights" (PDF). UNESCO. OCLC 932076434 . Retrieved October 22, 2015.
The goal of enhancing individuals and the human species by engineering the genes related to some characteristics and traits is not to be confused with the barbarous projects of eugenics that planned the simple elimination of human beings considered as 'imperfect' on an ideological basis. However, it impinges upon the principle of respect for human dignity in several ways. It weakens the idea that the differences among human beings, regardless of the measure of their endowment, are exactly what the recognition of their equality presupposes and therefore protects. It introduces the risk of new forms of discrimination and stigmatization for those who cannot afford such enhancement or simply do not want to resort to it. The arguments that have been produced in favour of the so-called liberal eugenics do not trump the indication to apply the limit of medical reasons also in this case.