Norcantharidin

Norcantharidin
Names
	Other names Endothall anhydride; 3,6-Endoxohexahydrophthalic anhydride
Identifiers
CAS Number	5442-12-6 ;
3D model (JSmol)	Interactive image ;
ChEMBL	ChEMBL1237212 ;
ChemSpider	8053159 ;
ECHA InfoCard	100.165.000
PubChem CID	9877482 ;
UNII	8452E71EO7 ;
CompTox Dashboard (EPA)	DTXSID30884158 ;
	InChI InChI=1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2/t3-,4+,5-,6+ Key: JAABVEXCGCXWRR-FBXFSONDSA-N;
	SMILES C1C[C@H]2[C@H]3[C@@H]([C@@H]1O2)C(=O)OC3=O;
Properties
Chemical formula	C8H8O4
Molar mass	168.148 g·mol−1
Appearance	white, solid
Melting point	115 °C (239 °F; 388 K)
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Xi
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Last updated October 01, 2025

Norcantharidin is a synthetic anticancer compound.^[1]

References

↑ Lv, H; Li, Y; Du, H; Fang, J; Song, X; Zhang, J (2013). "The Synthetic Compound Norcantharidin Induced Apoptosis in Mantle Cell Lymphoma in Vivo and in Vitro through the PI3K-Akt-NF- κ B Signaling Pathway". Evidence-Based Complementary and Alternative Medicine. 2013 461487. doi: 10.1155/2013/461487 . PMC 3722980 . PMID 23935664.

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[1] Lv, H; Li, Y; Du, H; Fang, J; Song, X; Zhang, J (2013). "The Synthetic Compound Norcantharidin Induced Apoptosis in Mantle Cell Lymphoma in Vivo and in Vitro through the PI3K-Akt-NF- κ B Signaling Pathway". Evidence-Based Complementary and Alternative Medicine. 2013 461487. doi: 10.1155/2013/461487 . PMC 3722980 . PMID 23935664.

[1]

Names

Other names Endothall anhydride; 3,6-Endoxohexahydrophthalic anhydride
Identifiers
CAS Number	5442-12-6 ^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1237212
ChemSpider	8053159
ECHA InfoCard	100.165.000
PubChem CID	9877482
UNII	8452E71EO7 ^Y
CompTox Dashboard (EPA)	DTXSID30884158
InChI InChI=1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2/t3-,4+,5-,6+ Key: JAABVEXCGCXWRR-FBXFSONDSA-N
SMILES C1C[C@H]2[C@H]3[C@@H]([C@@H]1O2)C(=O)OC3=O
Properties
Chemical formula	C₈H₈O₄
Molar mass	168.148 g·mol⁻¹
Appearance	white, solid
Melting point	115 °C (239 °F; 388 K)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Xi
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references