A radionuclide (radioactive nuclide, radioisotope or radioactive isotope) is a nuclide that has excess numbers of either neutrons or protons, giving it excess nuclear energy, and making it unstable. This excess energy can be used in one of three ways: emitted from the nucleus as gamma radiation; transferred to one of its electrons to release it as a conversion electron; or used to create and emit a new particle (alpha particle or beta particle) from the nucleus. During those processes, the radionuclide is said to undergo radioactive decay. These emissions are considered ionizing radiation because they are energetic enough to liberate an electron from another atom. The radioactive decay can produce a stable nuclide or will sometimes produce a new unstable radionuclide which may undergo further decay. Radioactive decay is a random process at the level of single atoms: it is impossible to predict when one particular atom will decay. However, for a collection of atoms of a single nuclide the decay rate, and thus the half-life (t1/2) for that collection, can be calculated from their measured decay constants. The range of the half-lives of radioactive atoms has no known limits and spans a time range of over 55 orders of magnitude.
Sterilization refers to any process that removes, kills, or deactivates all forms of life and other biological agents present in or on a specific surface, object, or fluid. Sterilization can be achieved through various means, including heat, chemicals, irradiation, high pressure, and filtration. Sterilization is distinct from disinfection, sanitization, and pasteurization, in that those methods reduce rather than eliminate all forms of life and biological agents present. After sterilization, an object is referred to as being sterile or aseptic.
TRIUMF is Canada's national particle accelerator centre. It is considered Canada's premier physics laboratory, and consistently regarded as one of the world's leading subatomic physics research centres. Owned and operated by a consortium of universities, it is on the south campus of one of its founding members, the University of British Columbia in Vancouver, British Columbia, Canada. It houses the world's largest normal conducting cyclotron, a source of 520 MeV protons, which was named an IEEE Milestone in 2010. Its accelerator-focused activities involve particle physics, nuclear physics, nuclear medicine, materials science, and detector and accelerator development.
Atomic Energy of Canada Limited (AECL) is a Canadian federal Crown corporation and Canada's largest nuclear science and technology laboratory. AECL developed the CANDU reactor technology starting in the 1950s, and in October 2011 licensed this technology to Candu Energy.
Bruce Nuclear Generating Station is a nuclear power station located on the eastern shore of Lake Huron in Ontario, Canada. It occupies 932 ha of land. The facility derives its name from Bruce Township, the local municipality when the plant was constructed, now Kincardine due to amalgamation. With eight CANDU pressurized heavy-water reactors, it was the world's largest fully operational nuclear generating station by total reactor count and the number of currently operational reactors until 2016, when it was exceeded in nameplate capacity by South Korea's Kori Nuclear Power Plant. The station is the largest employer in Bruce County, with over 4000 workers.
Wilfrid Bennett Lewis, was a Canadian nuclear scientist and administrator, and was centrally involved in the development of the CANDU reactor.
MAPLE, short for the Multipurpose Applied Physics Lattice Experiment, later renamed MDS Medical Isotope Reactors (MMIR), was a dedicated isotope-production facility built by AECL and MDS Nordion. It included two identical reactors, I and II, as well as the isotope-processing facilities necessary to produce a large portion of the world's medical isotopes, especially molybdenum-99, medical cobalt-60, xenon-133, iodine-131 and iodine-125.
Naturally occurring cobalt, Co, consists of a single stable isotope, 59Co. Twenty-eight radioisotopes have been characterized; the most stable are 60Co with a half-life of 5.2714 years, 57Co, 56Co, and 58Co. All other isotopes have half-lives of less than 18 hours and most of these have half-lives of less than 1 second. This element also has 11 meta states, all of which have half-lives of less than 15 minutes.
The National Research Universal (NRU) reactor was a 135 MW nuclear research reactor built in the Chalk River Laboratories, Ontario, one of Canada’s national science facilities. It was a multipurpose science facility that served three main roles. It generated radionuclides used to treat or diagnose over 20 million people in 80 countries every year. It was the neutron source for the NRC Canadian Neutron Beam Centre: a materials research centre that grew from the Nobel Prize-winning work of Bertram Brockhouse. It was the test bed for Atomic Energy of Canada Limited to develop fuels and materials for the CANDU reactor. At the time of its retirement on March 31, 2018, it was the world's oldest operating nuclear reactor.
The SLOWPOKE is a family of low-energy, tank-in-pool type nuclear research reactors designed by Atomic Energy of Canada Limited (AECL) beginning in the late 1960s. John W. Hilborn is the scientist most closely associated with their design. They are beryllium-reflected with a very low critical mass, but provide neutron fluxes higher than available from a small particle accelerator or other radioactive sources.
Cobalt-60 (60Co) is a synthetic radioactive isotope of cobalt with a half-life of 5.2714 years. It is produced artificially in nuclear reactors. Deliberate industrial production depends on neutron activation of bulk samples of the monoisotopic and mononuclidic cobalt isotope 59
Co
. Measurable quantities are also produced as a by-product of typical nuclear power plant operation and may be detected externally when leaks occur. In the latter case the incidentally produced 60
Co
is largely the result of multiple stages of neutron activation of iron isotopes in the reactor's steel structures via the creation of its 59
Co
precursor. The simplest case of the latter would result from the activation of 58
Fe
. 60
Co
undergoes beta decay to the stable isotope nickel-60. The activated cobalt nucleus emits two gamma rays with energies of 1.17 and 1.33 MeV, hence the overall equation of the nuclear reaction is: 59
27Co
+ n → 60
27Co
→ 60
28Ni
+ e− + 2 γ
Radionuclides which emit gamma radiation are valuable in a range of different industrial, scientific and medical technologies. This article lists some common gamma-emitting radionuclides of technological importance, and their properties.
Iodine-125 (125I) is a radioisotope of iodine which has uses in biological assays, nuclear medicine imaging and in radiation therapy as brachytherapy to treat a number of conditions, including prostate cancer, uveal melanomas, and brain tumors. It is the second longest-lived radioisotope of iodine, after iodine-129.
Technetium-99m (99mTc) is a metastable nuclear isomer of technetium-99, symbolized as 99mTc, that is used in tens of millions of medical diagnostic procedures annually, making it the most commonly used medical radioisotope in the world.
Cobalt therapy is the medical use of gamma rays from the radioisotope cobalt-60 to treat conditions such as cancer. Beginning in the 1950s, cobalt-60 was widely used in external beam radiotherapy (teletherapy) machines, which produced a beam of gamma rays which was directed into the patient's body to kill tumor tissue. Because these "cobalt machines" were expensive and required specialist support, they were often housed in cobalt units. Cobalt therapy was a revolutionary advance in radiotherapy in the post-World War II period but is now being replaced by other technologies such as linear accelerators.
Gold-198 (198Au) is a radioactive isotope of gold. It undergoes beta decay to stable 198Hg with a half-life of 2.69464 days.
Nuclear industry in Canada is an active business and research sector, producing about 15% of its electricity in nuclear power plants of domestic design. Canada is the world's largest exporter of uranium, and has the world's second largest proven reserves. Canada also exports nuclear technology within the terms of the Nuclear Non-proliferation Treaty, to which it is a signatory, and is the world's largest producer of radioactive medical isotopes.
A radioactive source is a known quantity of a radionuclide which emits ionizing radiation, typically one or more of the radiation types gamma rays, alpha particles, beta particles, and neutron radiation.
The Philippine Nuclear Research Institute (PNRI) is a government agency under the Department of Science and Technology mandated to undertake research and development activities in the peaceful uses of nuclear energy, institute regulations on the said uses, and carry out the enforcement of said regulations to protect the health and safety of radiation workers and the general public.
