OXA1L

Last updated
OXA1L
Identifiers
Aliases OXA1L , OXA1, mitochondrial inner membrane protein, OXA1L mitochondrial inner membrane protein
External IDs OMIM: 601066 MGI: 1916339 HomoloGene: 31281 GeneCards: OXA1L
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005015

NM_026936

RefSeq (protein)

NP_005006

NP_081212

Location (UCSC) Chr 14: 22.77 – 22.77 Mb Chr 14: 54.6 – 54.61 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Mitochondrial inner membrane protein OXA1L is a protein that in humans is encoded by the OXA1L gene located on 14q11.2. [5] The C-terminus of this protein interacts with mitochondrial ribosomes and helps insert both mitochondrial and nuclear produced proteins into the inner membrane of the mitochondria. [6] [7]

Reference

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000155463 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000000959 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Molina-Gomes D, Bonnefoy N, Nguyen VC, Viegas-Péquignot E, Rötig A, Dujardin G (1995). "The OXA1L gene that controls cytochrome oxidase assembly maps to the 14q11.2 region of the human genome". Genomics. 30 (2): 396–8. PMID   8586451.
  6. Haque ME, Elmore KB, Tripathy A, Koc H, Koc EC, Spremulli LL (2010). "Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes". The Journal of Biological Chemistry. 285 (36): 28353–62. doi: 10.1074/jbc.M110.148262 . PMC   2934699 . PMID   20601428.
  7. Haque ME, Spremulli LL, Fecko CJ (2010). "Identification of protein-protein and protein-ribosome interacting regions of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L". The Journal of Biological Chemistry. 285 (45): 34991–8. doi: 10.1074/jbc.M110.163808 . PMC   2966113 . PMID   20739282.

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