State Route 281 is an east–west state highway in the northwestern portion of the U.S. state of Ohio. Its western terminus is at U.S. Route 24 approximately four miles (6.4 km) northeast of downtown Defiance, and its eastern terminus is at US 6 nearly one mile (1.6 km) north of Bradner. The majority of the route is known as the Defiance Pike.
State Route 532 is a north–south state highway in the northeastern portion of the U.S. state of Ohio. The highway runs from its southern terminus at a signalized intersection with U.S. Route 224 (US 224) on the Summit–Portage county line approximately 0.75 miles (1.21 km) south of Mogadore on the border of Springfield Township and Suffield Township to its northern terminus at a diamond interchange with Interstate 76 (I-76), at its exit 29 within the Tallmadge city limits.
State Route 287 (SR 287) is a 13.69-mile-long (22.03 km) east–west state highway in the western portion of the U.S. state of Ohio. The western terminus of SR 287 is at SR 245 nearly 1.75 miles (2.82 km) east of West Liberty. Its eastern terminus is at an interchange with U.S. Route 33 (US 33) about 5.25 miles (8.45 km) northeast of North Lewisburg that dually serves as the southern terminus of SR 739.
State Route 797 was a very short, unsigned north–south state highway in the eastern portion of the U.S. state of Ohio. At the time of its deletion of the route from the state highway system, SR 797 ran from its southern terminus at the U.S. Route 22/U.S. Route 40 concurrency about 4.75 miles (7.64 km) northeast of Zanesville to its northern terminus less than 0.40 miles (0.64 km) to the northwest at Interstate 70 at its exit 160, a diamond interchange. North of the interchange, the road continues to Sonora on Muskingum County Road 52, Sonora Road.
State Route 621 is a north–south state highway in the central part of the U.S. state of Ohio. The southern terminus of SR 621 is at U.S. Route 36 approximately two and a half miles (4.0 km) northeast of Coshocton, and its northern terminus is adjacent to the North Appalachian Experimental Watershed Station, just north of its intersection with White Eyes Township Road 188, about 5 miles (8.0 km) northwest of the hamlet of Fresno. Continuing north after SR 621 ends is County Road 190.
State Route 546 is a north–south state highway in the northern portion of the U.S. state of Ohio. The southern terminus of SR 546 is at a T-intersection with SR 13 nearly two and a half miles (4.0 km) north of Fredericktown. Its northern terminus is at a signalized intersection with the U.S. Route 42 (US 42)/SR 97 concurrency in Lexington.
State Route 288 (SR 288) is a 6.82-mile (10.98 km) long east–west state highway in the northern portion of the U.S. state of Ohio. The western terminus of SR 288 is at a T-intersection with SR 309 about 3 miles (4.8 km) southwest of Galion. Its eastern terminus is also at a T-intersection, this time with SR 97 approximately 5.50 miles (8.85 km) northwest of Lexington.
State Route 664 is a north–south state highway in the southern portion of the U.S. state of Ohio. The highway has its southern terminus at a T-intersection with SR 56 in the unincorporated community of South Bloomingville. The northern terminus of SR 664 is also at a T-intersection, this time with SR 256 on the Fairfield–Perry county line approximately 4.75 miles (7.64 km) north of the village of Rushville.
State Route 211 (SR 211) is a 1.23-mile-long (1.98 km) north–south state highway in the eastern portion of the U.S. state of Ohio. Though physically it runs in a northwesterly–southeasterly direction, according to the Ohio Department of Transportation (ODOT) and signage on the route itself its southern terminus is located north of its northern terminus. The unusual directional signage is a vestige of when SR 211 traveled further south acting as a bypass of New Philadelphia and Dover. The highway runs from its signed southern terminus at a signalized intersection with SR 39 on the border of the city of Dover and Dover Township, just one block east of exit 83 off the Interstate 77 (I-77)/U.S. Route 250 (US 250) freeway, to its signed northern terminus at a signalized intersection with SR 800 near downtown Dover.
State Route 212 is a two-lane east–west state highway that runs within Stark, Tuscarawas, Carroll, and Harrison Counties in eastern Ohio. The western terminus of SR 212 is at U.S. Route 250 near Beach City, and its eastern terminus is at SR 151 in Bowerston. The route passes through rural areas but passes through small villages including Beach City, Bolivar, Zoar, Sherrodsville, and Leesville. It largely follows the valleys formed by the Tuscarawas River and Conotton Creek.
State Route 606 is a north–south state highway in the northeastern quadrant of the U.S. state of Ohio. The southern terminus of SR 606 is at a T-intersection with SR 3 approximately 4.50 miles (7.24 km) northeast of Medina. The highway's northern terminus is at another T-intersection, this time with the SR 94/SR 303 concurrency nearly 3.25 miles (5.23 km) west of Richfield.
State Route 672 (SR 672) is a 3.11-mile-long (5.01 km) east–west state highway in the southeastern part of the U.S. state of Ohio. The highway runs from its western terminus at a Y-intersection with SR 146 nearly 1.75 miles (2.82 km) northeast of Cumberland to its eastern terminus at a T-intersection with SR 821 about 3 miles (4.8 km) southwest of the village of Pleasant City.
State Route 374 is north–south state highway in Hocking County, Ohio, located in the southern portion of the state. Its southern terminus is over 4 miles (6.4 km) east of the unincorporated village of South Bloomingville at State Route 56, and its northern terminus is near the unincorporated village of Rockbridge at US 33, west of Logan. The road serves Hocking State Forest as well as Hocking Hills State Park, and the entire highway is part of the designated Hocking Hills Scenic Byway.
State Route 771 is a 7.11-mile-long (11.44 km) state highway located entirely in Highland County, Ohio. The north–south route connects SR 138 in Paint Township and SR 28 in Leesburg.
State Route 646 is a 28.78-mile-long (46.32 km) state highway in Harrison and Jefferson Counties in eastern Ohio. The route runs from US 250 in Stock Township, northwest of Cadiz, to SR 43 in Island Creek Township, just outside Wintersville.
State Route 668 is a north-south state highway in central Ohio. Its southern terminus is at an intersection with SR 93 in the Wayne National Forest, northeast of Logan; its northern terminus is at an intersection with US 40 in the unincorporated community of Brownsville.
State Route 674 is a state highway located southeast of Columbus, Ohio. Most of the route straddles a county line; about 11 miles (18 km) of the southern part of route is on the Pickaway–Fairfield County line while the next 1.4 miles (2.3 km) is on the Fairfield-Franklin County line. The route's southern terminus is at US 22 just north of Stoutsville while the northern terminus is at an interchange with US 33 in the city of Canal Winchester.
State Route 729 is a state highway in central Ohio. The 33.58-mile-long (54.04 km) route runs from SR 73 and SR 350 in the community of Snow Hill, northwest of New Vienna to SR 323 north of Jeffersonville.
