Olfactory receptor family 2 subfamily ag member 2

OR2AG2
Identifiers
Aliases	OR2AG2 , OR11-76, OR2AG2P, olfactory receptor family 2 subfamily AG member 2
External IDs	MGI: 3030535; HomoloGene: 12558; GeneCards: OR2AG2; OMA:OR2AG2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 6,765,626 bp [1] End 6,771,976 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 106,413,336 bp [2] End 106,420,679 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad prefrontal cortex duodenum primary visual cortex urinary bladder appendix muscle tissue olfactory zone of nasal mucosa islet of Langerhans Top expressed in spermatid olfactory epithelium zygote lumbar subsegment of spinal cord seminiferous tubule lumbar spinal ganglion oocyte gastrula primary oocyte secondary oocyte More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 338755 66786 Ensembl ENSG00000188124 ENSMUSG00000036744 UniProt A6NM03 n/a RefSeq (mRNA) NM_001004490 NM_001386053 NM_028910 NM_001360747 RefSeq (protein) NP_001004490 n/a Location (UCSC) Chr 11: 6.77 – 6.77 Mb Chr 7: 106.41 – 106.42 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor family 2 subfamily AG member 2 is a protein that in humans is encoded by the OR2AG2 gene. ^[5]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].

References

1. GRCh38: Ensembl release 89: ENSG00000188124 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036744 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Olfactory receptor family 2 subfamily AG member 2" . Retrieved 2018-02-21.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.