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PABPC5 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | PABPC5 , PABP5, poly(A) binding protein cytoplasmic 5 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 300407 MGI: 2136401 HomoloGene: 5857 GeneCards: PABPC5 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Poly(A) binding protein cytoplasmic 5 is a protein that in humans is encoded by the PABPC5 gene. [5]
This gene encodes a poly(A)-binding protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010].
Insulin-like growth factor 2 mRNA-binding protein 2 is a protein that in humans is encoded by the IGF2BP2 gene.
Cytoplasmic polyadenylation element-binding protein 1 is a protein that in humans is encoded by the CPEB1 gene.
PAB-dependent poly(A)-specific ribonuclease subunit 2 is an enzyme that in humans is encoded by the PAN2 gene.
CCR4-NOT transcription complex subunit 6 is a protein that in humans is encoded by the CNOT6 gene.
CTU2 is a human gene located on chromosome 16. The mRNA encodes the longer isoform. The gene encodes a cytoplasmic protein that plays a probable role in tRNA modification.
Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.
Chromosome 14 open reading frame 102 is a 3810bp protein-encoding gene that is highly conserved among its non-distant orthologs. It contains 20 introns and 8 different RNAs - 7 splice variants and 1 unspliced form - and is located on the reverse strand of chromosome 14 (14q32.11). The protein encoded by this gene belongs to the UPF0614 family of Up-frameshift proteins and has a molecular weight of 132.417 kDa and isoelectric point of 7.88. It is expected to have a protein binding function and localization in the cytoplasm.
Pre-mRNA-processing factor 40 homolog B is a protein that in humans that is encoded by the PRPF40B gene.
The E3 ubiquitin-protein ligase Hakai (HAKAI) also known as Casitas B-lineage lymphoma-transforming sequence-like protein 1 (CBLL1) is an enzyme that in humans is encoded by the CBLL1 gene. This gene encodes an E3 ubiquitin ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation.
WD repeat and HMG-box DNA binding protein 1 is a protein in humans that is encoded by the WDHD1 gene.
Poly(A) binding protein, cytoplasmic 4-like is a protein that in humans is encoded by the PABPC4L gene.
Acrosin binding protein is a protein that in humans is encoded by the ACRBP gene.
PAN3 poly(A) specific ribonuclease subunit is a protein that in humans is encoded by the PAN3 gene.
Forkhead box S1 is a protein that in humans is encoded by the FOXS1 gene.
Mitochondrial ribosomal protein S2 (MRPS2), otherwise known as uS2m, is a protein that in humans is encoded by the MRPS2 gene.
Mitochondrial ribosomal protein S9 (MRPS9), otherwise known as uS9m, is a protein that in humans is encoded by the MRPS9 gene.
Poly(A) binding protein interacting protein 2B is a protein that in humans is encoded by the PAIP2B gene.
NOVA alternative splicing regulator 2 is a protein that in humans is encoded by the NOVA2 gene.
RNA binding motif protein 44 is a protein that in humans is encoded by the RBM44 gene.
Ribosomal protein L36a like is a protein that in humans is encoded by the RPL36AL gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.